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Anomaly detection (AD) is the identification of data samples that do not fit a learned data distribution. As such, AD systems can help physicians to determine the presence, severity, and extension of a pathology. Deep generative models,…

Image and Video Processing · Electrical Eng. & Systems 2021-04-12 Jaime Simarro , Ezequiel de la Rosa , Thijs Vande Vyvere , David Robben , Diana M. Sima

Electron, optical, and scanning probe microscopy methods are generating ever increasing volume of image data containing information on atomic and mesoscale structures and functionalities. This necessitates the development of the machine…

Machine Learning · Computer Science 2023-04-03 Mani Valleti , Yongtao Liu , Sergei Kalinin

Anomaly detection plays a pivotal role in numerous real-world scenarios, such as industrial automation and manufacturing intelligence. Recently, variational inference-based anomaly analysis has attracted researchers' and developers'…

Computer Vision and Pattern Recognition · Computer Science 2022-03-10 Yurong Chen

Medical anomaly detection (AD) is crucial in pathological identification and localization. Current methods typically rely on uncertainty estimation in deep ensembles to detect anomalies, assuming that ensemble learners should agree on…

Computer Vision and Pattern Recognition · Computer Science 2024-09-27 Yi Gu , Yi Lin , Kwang-Ting Cheng , Hao Chen

Unsupervised anomaly detection in medical images such as chest radiographs is stepping into the spotlight as it mitigates the scarcity of the labor-intensive and costly expert annotation of anomaly data. However, nearly all existing methods…

Computer Vision and Pattern Recognition · Computer Science 2023-07-31 Behzad Bozorgtabar , Dwarikanath Mahapatra , Jean-Philippe Thiran

Automated medical image segmentation inherently involves a certain degree of uncertainty. One key factor contributing to this uncertainty is the ambiguity that can arise in determining the boundaries of a target region of interest,…

Image and Video Processing · Electrical Eng. & Systems 2023-08-28 Qingqiao Hu , Hao Wang , Jing Luo , Yunhao Luo , Zhiheng Zhangg , Jan S. Kirschke , Benedikt Wiestler , Bjoern Menze , Jianguo Zhang , Hongwei Bran Li

The Masked Autoencoder (MAE) has recently demonstrated effectiveness in pre-training Vision Transformers (ViT) for analyzing natural images. By reconstructing complete images from partially masked inputs, the ViT encoder gathers contextual…

Image and Video Processing · Electrical Eng. & Systems 2025-06-03 Badhan Kumar Das , Gengyan Zhao , Han Liu , Thomas J. Re , Dorin Comaniciu , Eli Gibson , Andreas Maier

Anomaly detection is a critical task across numerous domains and modalities, yet existing methods are often highly specialized, limiting their generalizability. These specialized models, tailored for specific anomaly types like textural…

Computer Vision and Pattern Recognition · Computer Science 2025-08-11 Zhaopeng Gu , Bingke Zhu , Guibo Zhu , Yingying Chen , Wei Ge , Ming Tang , Jinqiao Wang

Autoencoders, as a dimensionality reduction technique, have been recently applied to outlier detection. However, neural networks are known to be vulnerable to overfitting, and therefore have limited potential in the unsupervised outlier…

Machine Learning · Computer Science 2019-10-23 Hamed Sarvari , Carlotta Domeniconi , Bardh Prenkaj , Giovanni Stilo

Anomaly detection without priors of the anomalies is challenging. In the field of unsupervised anomaly detection, traditional auto-encoder (AE) tends to fail based on the assumption that by training only on normal images, the model will not…

Computer Vision and Pattern Recognition · Computer Science 2024-08-15 Yajie Cui , Zhaoxiang Liu , Shiguo Lian

Among other uses, neural networks are a powerful tool for solving deterministic and Bayesian inverse problems in real-time, where variational autoencoders, a specialized type of neural network, enable the Bayesian estimation of model…

Machine Learning · Computer Science 2025-09-25 Andrea Tonini , Luca Dede'

Variational autoencoder (VAE) is an established generative model but is notorious for its blurriness. In this work, we investigate the blurry output problem of VAE and resolve it, exploiting the variance of Gaussian decoder and $\beta$ of…

Machine Learning · Computer Science 2024-09-17 Seunghwan Kim , Seungkyu Lee

Deep learning (DL) algorithms can be used to automate paranasal anomaly detection from Magnetic Resonance Imaging (MRI). However, previous works relied on supervised learning techniques to distinguish between normal and abnormal samples.…

Identification of defects or anomalies in 3D objects is a crucial task to ensure correct functionality. In this work, we combine Bayesian learning with recent developments in quantum and quantum-inspired machine learning, specifically…

Anomaly detection is a classical but worthwhile problem, and many deep learning-based anomaly detection algorithms have been proposed, which can usually achieve better detection results than traditional methods. In view of reconstruct…

Machine Learning · Computer Science 2020-04-16 Chunkai Zhang , Shaocong Li , Hongye Zhang , Yingyang Chen

In anomaly detection (AD), one seeks to identify whether a test sample is abnormal, given a data set of normal samples. A recent and promising approach to AD relies on deep generative models, such as variational autoencoders (VAEs), for…

Machine Learning · Computer Science 2021-11-05 Tal Daniel , Thanard Kurutach , Aviv Tamar

The problem of detecting the Out-of-Distribution (OoD) inputs is of paramount importance for Deep Neural Networks. It has been previously shown that even Deep Generative Models that allow estimating the density of the inputs may not be…

Machine Learning · Statistics 2023-01-02 Misha Glazunov , Apostolis Zarras

We introduce an anomaly detection method for multivariate time series data with the aim of identifying critical periods and features influencing extreme climate events like snowmelt in the Arctic. This method leverages the Variational…

Machine Learning · Computer Science 2024-07-16 Tolulope Ale , Nicole-Jeanne Schlegel , Vandana P. Janeja

Reliable anomaly detection in brain MRI remains challenging due to the scarcity of annotated abnormal cases and the frequent absence of key imaging modalities in real clinical workflows. Existing single-class or multi-class anomaly…

Computer Vision and Pattern Recognition · Computer Science 2025-12-25 Changwei Wu , Yifei Chen , Yuxin Du , Mingxuan Liu , Jinying Zong , Beining Wu , Jie Dong , Feiwei Qin , Yunkang Cao , Qiyuan Tian

Image-based precision medicine aims to personalize treatment decisions based on an individual's unique imaging features so as to improve their clinical outcome. Machine learning frameworks that integrate uncertainty estimation as part of…

Machine Learning · Computer Science 2023-08-11 Joshua Durso-Finley , Jean-Pierre Falet , Raghav Mehta , Douglas L. Arnold , Nick Pawlowski , Tal Arbel