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Related papers: Bacterial chemotaxis considering memory effects

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The Escherichia coli chemoreceptors form an extensive array that achieves cooperative and adaptive sensing of extracellular signals. The receptors control the activity of histidine kinase CheA, which drives a nonequilibrium…

Biological Physics · Physics 2025-01-24 David Hathcock , Qiwei Yu , Yuhai Tu

Chemotaxis and haptotaxis have been a main theme in the macroscopic study of bacterial and cellular motility. In this work we investigate the influence these processes have on the shape and motility of fast migrating cells. We note that…

Cell Behavior · Quantitative Biology 2016-12-08 Aaron Brunk , Niklas Kolbe , Nikolaos Sfakianakis

We study chemotaxis of a single {\sl E.coli} bacterium in a medium where the nutrient chemical is also undergoing diffusion and its concentration has the form of a Gaussian whose width increases with time. We measure the average first…

Cell Behavior · Quantitative Biology 2015-04-30 Subrata Dev , Sakuntala Chatterjee

The flux limited Keller-Segel (FLKS) system is a macroscopic model describing bacteria motion by chemotaxis which takes into account saturation of the velocity. The hyper-bolic form and some special parabolic forms have been derived from…

Analysis of PDEs · Mathematics 2018-01-23 Benoît Perthame , Nicolas Vauchelet , Zhian Wang

Chemotaxis is the process by which cells behave in a way that follows the chemical gradient. Applications to bacteria growth, tissue inflammation, and vascular tumors provide a focus on optimization strategies. Experiments can characterize…

Optimization and Control · Mathematics 2007-07-18 K. Renee Fister , Maeve L. McCarthy

We introduce stochastic models of chemotaxis generalizing the deterministic Keller-Segel model. These models include fluctuations which are important in systems with small particle numbers or close to a critical point. Following Dean's…

Statistical Mechanics · Physics 2009-09-01 Pierre-Henri Chavanis

Recent genomic analyses on the cellular metabolic network show that reaction flux across enzymes are diverse and exhibit power-law behavior in its distribution. While one may guess that the reactions with larger fluxes are more likely to be…

Molecular Networks · Quantitative Biology 2007-05-23 C. -M. Ghim , K. -I. Goh , B. Kahng

We analyse the time dependent non-linear rheology of a dilute bacterial suspension (e.g. E. coli) for a pair of impulsively started linear flows - simple shear and uniaxial extension. The rheology is governed by the bacterium orientation…

Fluid Dynamics · Physics 2019-06-26 Sankalp Nambiar , Phanikanth S , Nott P. R. , Ganesh Subramanian

Enzymes show two distinct transport behaviors in the presence of their substrates in solution. First, their diffusivity enhances with increasing substrate concentration. In addition, enzymes perform directional motion toward regions with…

Biological Physics · Physics 2018-11-06 Farzad Mohajerani , Xi Zhao , Ambika Somasundar , Darrell Velegol , Ayusman Sen

Motility is fundamental to the survival and proliferation of microorganisms. The E. coli bacterium propels itself using a bundle of rotating helical flagella. If one flagellum reverses its rotational direction, it leaves the bundle,…

Soft Condensed Matter · Physics 2025-04-30 Pierre Martin , Tapan Chandra Adhyapak , Holger Stark

Cell migration in vivo is often guided by chemical signals. Such chemotaxis, such as performed by immune cells migrating to a wound site, is complicated by the complex geometry inside living tissues. In this study, we extend our theoretical…

In many situations bacteria move in complex environments, as for example in soils, oceans or the human gut-track microbiome. In these natural environments, carrier fluids such as mucus or reproductive fluids show complex structure…

Soft Condensed Matter · Physics 2022-06-22 Martyna Goral , Eric Clement , Thierry Darnige , Teresa Lopez-Leon , Anke Lindner

Chemotaxis receptors in E. coli form clusters at the cell poles and also laterally along the cell body, and this clustering plays an important role in signal transduction. Recently, experiments using flourrescence imaging have shown that,…

Statistical Mechanics · Physics 2008-11-29 Hui Wang , Ned S. Wingreen , Ranjan Mukhopadhyay

Autologous chemotaxis, in which cells secrete and detect molecules to determine the direction of fluid flow, is thwarted at high cell density because molecules from other cells interfere with a given cell's signal. Using a minimal model of…

Biological Physics · Physics 2022-09-14 Michael Vennettilli , Louis Gonzalez , Nicholas Hilgert , Andrew Mugler

A novel trait-structured Keller-Segel model that explores the dynamics of a migrating cell population guided by chemotaxis in response to an external ligand concentration is derived and analysed. Unlike traditional Keller-Segel models, this…

Cell Behavior · Quantitative Biology 2025-02-27 Viktoria Freingruber , Tommaso Lorenzi , Kevin J. Painter , Mariya Ptashnyk

Sedimentation in active fluids has come into focus due to the ubiquity of swimming micro-organisms in natural and industrial processes. Here, we investigate sedimentation dynamics of passive particles in a fluid as a function of bacteria E.…

Bacterial growth environment strongly influences the efficacy of antibiotic treatment, with slow growth often being associated with decreased susceptibility. Yet in many cases the connection between antibiotic susceptibility and pathogen…

Cell Behavior · Quantitative Biology 2015-05-06 Philip Greulich , Matthew Scott , Martin R. Evans , Rosalind J. Allen

Sensory adaptation enables organisms to adjust their perception in a changing environment. A paradigm is bacterial chemotaxis, where the output activity of chemoreceptors is adapted to different baseline concentrations via receptor…

Cell Behavior · Quantitative Biology 2024-01-23 Vansh Kharbanda , Benedikt Sabass

We consider self-propelled particles undergoing run-and-tumble dynamics (as exhibited by E. coli) in one dimension. Building on previous analyses at drift-diffusion level for the one-particle density, we add both interactions and noise,…

Statistical Mechanics · Physics 2008-08-14 J. Tailleur , M. E. Cates

The aim of this paper is to analyze a model for chemotaxis based on a local sensing mechanism instead of the gradient sensing mechanism used in the celebrated minimal Keller-Segel model. The model we study has the same entropy as the…

Analysis of PDEs · Mathematics 2020-06-05 Martin Burger , Philippe Laurençot , Ariane Trescases