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Quantum computing promises to solve difficult optimization problems in chemistry, physics and mathematics more efficiently than classical computers, but requires fault-tolerant quantum computers with millions of qubits. To overcome errors…

Databases · Computer Science 2021-07-23 Tobias Fankhauser , Marc E. Solèr , Rudolf M. Füchslin , Kurt Stockinger

Background: Beam angle optimization (BAO) is a critical component of radiation therapy (RT) treatment planning, where small changes in beam configuration can significantly impact treatment quality, especially for proton RT. Mathematically,…

Medical Physics · Physics 2025-09-08 Nimita Shinde , Ya-Nan Zhu , Haozheng Shen , Hao Gao

Constrained binary optimization aims to find an optimal assignment to minimize or maximize the objective meanwhile satisfying the constraints, which is a representative NP problem in various domains, including transportation, scheduling,…

Quantum Physics · Physics 2025-08-18 Debin Xiang , Qifan Jiang , Liqiang Lu , Siwei Tan , Jianwei Yin

A novel distributed algorithm is proposed for finite-time converging to a feasible consensus solution satisfying global optimality to a certain accuracy of the distributed robust convex optimization problem (DRCO) subject to bounded…

Optimization and Control · Mathematics 2023-09-06 Xunhao Wu , Jun Fu

Quadratic unconstrained binary optimization (QUBO) has become the standard format for optimization using quantum computers, i.e., for both the quantum approximate optimization algorithm (QAOA) and quantum annealing (QA). We present a…

Quantum Physics · Physics 2022-04-26 Thomas Gabor , Marian Lingsch Rosenfeld , Sebastian Feld , Claudia Linnhoff-Popien

Many artificial intelligence (AI) problems naturally map to NP-hard optimization problems. This has the interesting consequence that enabling human-level capability in machines often requires systems that can handle formally intractable…

Quantum Physics · Physics 2009-09-29 Hartmut Neven , Geordie Rose , William G. Macready

Ising machines, including quantum annealing machines, are promising next-generation computers for combinatorial optimization problems. However, due to hardware limitations, most Ising-type hardware can only solve objective functions…

Statistical Mechanics · Physics 2025-10-29 Kazuki Ikeuchi , Yoshiki Matsuda , Shu Tanaka

We experimentally demonstrate that a digitized counterdiabatic quantum protocol reduces the number of topological defects created during a fast quench across a quantum phase transition. To show this, we perform quantum simulations of one-…

We study the performance scaling of three quantum algorithms for combinatorial optimization: measurement-feedback coherent Ising machines (MFB-CIM), discrete adiabatic quantum computation (DAQC), and the D\"urr-Hoyer algorithm for quantum…

Although quantum computing holds promise for solving Combinatorial Optimization Problems (COPs), the limited qubit capacity of NISQ hardware makes large-scale instances intractable. Conventional methods attempt to bridge this gap through…

Quantum Physics · Physics 2026-01-21 Yuhan Huang , Siyuan Jin , Yichi Zhang , Qi Zhao , Jun Qi , Qiming Shao

In the field of quantum computing, combinatorial optimization problems are typically addressed using QUBO (Quadratic Unconstrained Binary Optimization) solvers. However, these solvers are often insufficient for tackling higher-order…

Quantum Physics · Physics 2024-07-24 Yuichiro Minato

We propose Discrete Consensus-Based Optimization (DCBO), a fully discrete version of the Consensus-Based Optimization (CBO) framework. DCBO is a multi-agent method for the global optimization of possibly non-convex and non-differentiable…

Optimization and Control · Mathematics 2024-04-17 Junhyeok Byeon , Seung-Yeal Ha , Joong-Ho Won

The global optimization of a high-dimensional black-box function under black-box constraints is a pervasive task in machine learning, control, and engineering. These problems are challenging since the feasible set is typically non-convex…

Machine Learning · Computer Science 2021-03-02 David Eriksson , Matthias Poloczek

Black-box optimization minimizes an objective function without derivatives or explicit forms. Such an optimization method with continuous variables has been successful in the fields of machine learning and material science. For discrete…

We present a new method that efficiently solves TO problems and provides a practical pathway to leverage quantum computing to exploit potential quantum advantages. This work targets on large-scale, multi-material TO challenges for…

Computational Physics · Physics 2026-01-16 Zisheng Ye , Wenxiao Pan

Variational quantum algorithms have been advocated as promising candidates to solve combinatorial optimization problems on near-term quantum computers. Their methodology involves transforming the optimization problem into a quadratic…

Quantum Physics · Physics 2023-08-01 Zoé Verchère , Sourour Elloumi , Andrea Simonetto

Quantum computing holds great potential to accelerate the process of solving complex combinatorial optimization problems. The Distributed Quantum Approximate Optimization Algorithm (DQAOA) addresses high-dimensional, dense problems using…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-06-13 Zhihao Xu , Srikar Chundury , Seongmin Kim , Amir Shehata , Xinyi Li , Ang Li , Tengfei Luo , Frank Mueller , In-Saeng Suh

With the development of quantum computing, the use of quantum algorithms to solve combinatorial optimization problems on quantum computers has become a major research focus. The Quadratic Unconstrained Binary Optimization (QUBO) model…

Computational Engineering, Finance, and Science · Computer Science 2025-04-10 Haoqian Pan , Changhong Lu

Bayesian optimization is a popular method for optimizing expensive black-box functions. Yet it oftentimes struggles in high dimensions where the computation could be prohibitively heavy. To alleviate this problem, we introduce Coordinate…

Machine Learning · Computer Science 2022-04-21 Jian Tan , Niv Nayman , Mengchang Wang

The LogQ algorithm encodes Quadratic Unconstrained Binary Optimization (QUBO) problems, which are often encountered in the industry (portfolio optimization, fleet optimization, charging stations, etc.). It was developed within the framework…

Optimization and Control · Mathematics 2026-04-15 Jérémie Messud , Yagnik Chatterjee