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Domain specific large language models are increasingly used to support patient education, triage, and clinical decision making in ophthalmology, making rigorous evaluation essential to ensure safety and accuracy. This study evaluated four…

We present an approach to build Large Language Model (LLM) based slot-filling system to perform Dialogue State Tracking in conversational assistants serving across a wide variety of industry-grade applications. Key requirements of this…

Large language models have been adopted in the medical domain for clinical documentation to reduce clinician burden. However, studies have reported that LLMs often "forget" a significant amount of instruction-following ability when…

Computation and Language · Computer Science 2026-04-03 Mengxian Lyu , Cheng Peng , Ziyi Chen , Mengyuan Zhang , Jieting Li Lu , Yonghui Wu

Inaccuracies in existing or generated clinical text may lead to serious adverse consequences, especially if it is a misdiagnosis or incorrect treatment suggestion. With Large Language Models (LLMs) increasingly being used across diverse…

Computation and Language · Computer Science 2026-02-06 Congbo Ma , Yichun Zhang , Yousef Al-Jazzazi , Ahamed Foisal , Laasya Sharma , Yousra Sadqi , Khaled Saleh , Jihad Mallat , Farah E. Shamout

This paper introduces a system that integrates large language models (LLMs) into the clinical trial retrieval process, enhancing the effectiveness of matching patients with eligible trials while maintaining information privacy and allowing…

Information Retrieval · Computer Science 2024-11-01 Georgios Peikos , Pranav Kasela , Gabriella Pasi

Large language models (LLMs) have demonstrated strong performance on medical benchmarks, including question answering and diagnosis. To enable their use in clinical settings, LLMs are typically further adapted through continued pretraining…

In record linkage (RL), or exact file matching, the goal is to identify the links between entities with information on two or more files. RL is an important activity in areas including counting the population, enhancing survey frames and…

Statistics Theory · Mathematics 2012-12-21 Michael D. Larsen

This paper addresses the gap between general-purpose text embeddings and the specific demands of item retrieval tasks. We demonstrate the shortcomings of existing models in capturing the nuances necessary for zero-shot performance on item…

Information Retrieval · Computer Science 2024-03-01 Yuxuan Lei , Jianxun Lian , Jing Yao , Mingqi Wu , Defu Lian , Xing Xie

Clinical trials are essential for drug development but often suffer from expensive, inaccurate and insufficient patient recruitment. The core problem of patient-trial matching is to find qualified patients for a trial, where patient…

Artificial Intelligence · Computer Science 2021-04-13 Xingyao Zhang , Cao Xiao , Lucas M. Glass , Jimeng Sun

Large Language Models (LLMs) have demonstrated impressive capabilities across diverse Natural Language Processing (NLP) tasks, including language understanding, reasoning, and generation. However, general-domain LLMs often struggle with…

Computation and Language · Computer Science 2024-11-06 Sorouralsadat Fatemi , Yuheng Hu , Maryam Mousavi

Clustering patient subgroups is essential for personalized care and efficient resource use. Traditional clustering methods struggle with high-dimensional, heterogeneous healthcare data and lack contextual understanding. This study evaluates…

Large language models, such as GPT-4 and Med-PaLM, have shown impressive performance on clinical tasks; however, they require access to compute, are closed-source, and cannot be deployed on device. Mid-size models such as BioGPT-large,…

Large language models (LLMs) hold promise for transforming healthcare, from streamlining administrative and clinical workflows to enriching patient engagement and advancing clinical decision-making. However, their successful integration…

Computers and Society · Computer Science 2025-04-04 Mohammed Al-Garadi , Tushar Mungle , Abdulaziz Ahmed , Abeed Sarker , Zhuqi Miao , Michael E. Matheny

Patient recruitment is challenging for clinical trials. We introduce TrialGPT, an end-to-end framework for zero-shot patient-to-trial matching with large language models. TrialGPT comprises three modules: it first performs large-scale…

Large Language Models (LLMs) have demonstrated remarkable adaptability, showcasing their capacity to excel in tasks for which they were not explicitly trained. However, despite their impressive natural language processing (NLP)…

Computation and Language · Computer Science 2023-09-08 Supun Manathunga , Isuru Hettigoda

This paper proposes a novel training scheme for fast matching models in Search Ads, which is motivated by the real challenges in model training. The first challenge stems from the pursuit of high throughput, which prohibits the deployment…

Information Retrieval · Computer Science 2019-04-23 Xue Li , Zhipeng Luo , Hao Sun , Jianjin Zhang , Weihao Han , Xianqi Chu , Liangjie Zhang , Qi Zhang

This study evaluates how well large language models (LLMs) can classify ICD-10 codes from hospital discharge summaries, a critical but error-prone task in healthcare. Using 1,500 summaries from the MIMIC-IV dataset and focusing on the 10…

Computation and Language · Computer Science 2025-07-08 Akram Mustafa , Usman Naseem , Mostafa Rahimi Azghadi

Accurate clinical coding is essential for healthcare documentation, billing, and decision-making. While prior work shows that off-the-shelf LLMs struggle with this task, evaluations based on exact match metrics often overlook errors where…

Computation and Language · Computer Science 2025-10-10 Zhangdie Yuan , Han-Chin Shing , Mitch Strong , Chaitanya Shivade

Scientific research indicates that for every hour spent in direct patient care, physicians spend nearly two additional hours on administrative tasks, particularly on electronic health records (EHRs) and desk work. This excessive…

Computation and Language · Computer Science 2025-09-25 Hui Yi Leong , Yi Fan Gao , Ji Shuai , Yang Zhang , Uktu Pamuksuz

Large Language Models (LLMs) consistently excel in diverse medical Natural Language Processing (NLP) tasks, yet their substantial computational requirements often limit deployment in real-world healthcare settings. In this work, we…

Computation and Language · Computer Science 2026-02-20 Pietro Ferrazzi , Mattia Franzin , Alberto Lavelli , Bernardo Magnini