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Applying machine learning to real-world medical data, e.g. from hospital archives, has the potential to revolutionize disease detection in brain images. However, detecting pathology in such heterogeneous cohorts is a difficult challenge.…

Image and Video Processing · Electrical Eng. & Systems 2025-08-06 Ana Lawry Aguila , Ayodeji Ijishakin , Juan Eugenio Iglesias , Tomomi Takenaga , Yukihiro Nomura , Takeharu Yoshikawa , Osamu Abe , Shouhei Hanaoka

Anatomical atlases are widely used for population studies and analysis. Conditional atlases target a specific sub-population defined via certain conditions, such as demographics or pathologies, and allow for the investigation of…

Image and Video Processing · Electrical Eng. & Systems 2025-06-25 Sophie Starck , Vasiliki Sideri-Lampretsa , Bernhard Kainz , Martin J. Menten , Tamara T. Mueller , Daniel Rueckert

In the field of medical imaging, particularly in tasks related to early disease detection and prognosis, understanding the reasoning behind AI model predictions is imperative for assessing their reliability. Conventional explanation methods…

Computer Vision and Pattern Recognition · Computer Science 2024-06-28 Yingying Fang , Shuang Wu , Zihao Jin , Caiwen Xu , Shiyi Wang , Simon Walsh , Guang Yang

Image classification models tend to make decisions based on peripheral attributes of data items that have strong correlation with a target variable (i.e., dataset bias). These biased models suffer from the poor generalization capability…

Machine Learning · Computer Science 2021-10-26 Jungsoo Lee , Eungyeup Kim , Juyoung Lee , Jihyeon Lee , Jaegul Choo

The problem of fair classification can be mollified if we develop a method to remove the embedded sensitive information from the classification features. This line of separating the sensitive information is developed through the causal…

Machine Learning · Computer Science 2020-12-10 Hyemi Kim , Seungjae Shin , JoonHo Jang , Kyungwoo Song , Weonyoung Joo , Wanmo Kang , Il-Chul Moon

We introduce a simple but effective unsupervised method for generating realistic and diverse images. We train a class-conditional GAN model without using manually annotated class labels. Instead, our model is conditional on labels…

Computer Vision and Pattern Recognition · Computer Science 2022-02-11 Steven Liu , Tongzhou Wang , David Bau , Jun-Yan Zhu , Antonio Torralba

Diffusion models have achieved impressive performance in generating high-quality and diverse synthetic data. However, their success typically assumes a class-balanced training distribution. In real-world settings, multi-class data often…

This article presents a general Bayesian learning framework for multi-modal groupwise image registration. The method builds on probabilistic modelling of the image generative process, where the underlying common anatomy and geometric…

Computer Vision and Pattern Recognition · Computer Science 2025-09-16 Xinzhe Luo , Xin Wang , Linda Shapiro , Chun Yuan , Jianfeng Feng , Xiahai Zhuang

Generative data augmentation with latent diffusion models is a promising strategy for addressing class imbalance in medical imaging, yet current approaches focus on perceptual fidelity and domain-specific autoencoder fine-tuning while…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Mischa Dombrowski , Felix Nützel , Bernhard Kainz

While score based generative models, or diffusion models, have found success in image synthesis, they are often coupled with text data or image label to be able to manipulate and conditionally generate images. Even though manipulation of…

Computer Vision and Pattern Recognition · Computer Science 2023-02-07 Sandesh Ghimire , Armand Comas , Davin Hill , Aria Masoomi , Octavia Camps , Jennifer Dy

Beyond generating long and topic-coherent paragraphs in traditional captioning tasks, the medical image report composition task poses more task-oriented challenges by requiring both the highly-accurate medical term diagnosis and multiple…

Computation and Language · Computer Science 2021-01-12 Fuyu Wang , Xiaodan Liang , Lin Xu , Liang Lin

Deep neural networks have brought remarkable breakthroughs in medical image analysis. However, due to their data-hungry nature, the modest dataset sizes in medical imaging projects might be hindering their full potential. Generating…

Spatial profiling technologies in biology, such as imaging mass cytometry (IMC) and spatial transcriptomics (ST), generate high-dimensional, multi-channel data with strong spatial alignment and complex inter-channel relationships.…

Machine Learning · Computer Science 2025-07-08 Haoran Zhang , Mingyuan Zhou , Wesley Tansey

Language-guided image generation has achieved great success nowadays by using diffusion models. However, texts can be less detailed to describe highly-specific subjects such as a particular dog or a certain car, which makes pure…

Computer Vision and Pattern Recognition · Computer Science 2023-03-17 Yiyang Ma , Huan Yang , Wenjing Wang , Jianlong Fu , Jiaying Liu

While deep learning methods have shown great success in medical image analysis, they require a number of medical images to train. Due to data privacy concerns and unavailability of medical annotators, it is oftentimes very difficult to…

Image and Video Processing · Electrical Eng. & Systems 2020-10-08 Yue Yang , Pengtao Xie

The image-based diagnosis is now a vital aspect of modern automation assisted diagnosis. To enable models to produce pixel-level diagnosis, pixel-level ground-truth labels are essentially required. However, since it is often not straight…

Computer Vision and Pattern Recognition · Computer Science 2023-01-24 Tehseen Zia , Zeeshan Nisar , Shakeeb Murtaza

Recent advancements in large scale text-to-image models have opened new possibilities for guiding the creation of images through human-devised natural language. However, while prior literature has primarily focused on the generation of…

Computer Vision and Pattern Recognition · Computer Science 2023-02-09 Hyeonho Jeong , Gihyun Kwon , Jong Chul Ye

Pseudo healthy synthesis, i.e. the creation of a subject-specific `healthy' image from a pathological one, could be helpful in tasks such as anomaly detection, understanding changes induced by pathology and disease or even as data…

Computer Vision and Pattern Recognition · Computer Science 2019-01-23 Tian Xia , Agisilaos Chartsias , Sotirios A. Tsaftaris

In the field of computational pathology, deep learning algorithms have made significant progress in tasks such as nuclei segmentation and classification. However, the potential of these advanced methods is limited by the lack of available…

Computer Vision and Pattern Recognition · Computer Science 2024-07-22 Hyun-Jic Oh , Won-Ki Jeong

Leveraging the powerful capabilities of diffusion models has yielded quite effective results in medical image segmentation tasks. However, existing methods typically transfer the original training process directly without specific…

Computer Vision and Pattern Recognition · Computer Science 2025-07-25 Qilin Huang , Tianyu Lin , Zhiguang Chen , Fudan Zheng
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