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Ultrasound-based risk stratification of thyroid nodules is a critical clinical task, but it suffers from high inter-observer variability. While many deep learning (DL) models function as "black boxes," we propose a fully automated,…

Image and Video Processing · Electrical Eng. & Systems 2025-11-18 Omar Abdelrazik , Mohamed Elsayed , Noorul Wahab , Nasir Rajpoot , Adam Shephard

Thyroid cancer is among the most common cancers in the United States. Thyroid nodules are frequently detected through ultrasound (US) imaging, and some require further evaluation via fine-needle aspiration (FNA) biopsy. Despite its…

In this study, we develop a new CAD system for accurate thyroid cancer classification with emphasis on feature extraction. Prior studies have shown that thyroid texture is important for segregating the thyroid ultrasound images into…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Saurabh Saini , Kapil Ahuja , Marc C. Steinbach , Thomas Wick

Thyroid nodule classification using ultrasound imaging is essential for early diagnosis and clinical decision-making; however, despite promising performance on in-distribution data, existing deep learning methods often exhibit limited…

Computer Vision and Pattern Recognition · Computer Science 2026-03-31 Yangmei Chen , Zhongyuan Zhang , Xikun Zhang , Xinyu Hao , Mingliang Hou , Renqiang Luo , Ziqi Xu

Purpose: Thyroid scintigraphy plays a vital role in diagnosing a range of thyroid disorders. While deep learning classification models hold significant promise in this domain, their effectiveness is frequently compromised by limited and…

The objective of this study was to develop an automated pipeline that enhances thyroid disease classification using thyroid scintigraphy images, aiming to decrease assessment time and increase diagnostic accuracy. Anterior thyroid…

Timely and accurate diagnosis is crucial in addressing the global rise in thyroid cancer, ensuring effective treatment strategies and improved patient outcomes. We present an intelligent classification method that couples an Adaptive…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Nada Bouchekout , Abdelkrim Boukabou , Morad Grimes , Yassine Habchi , Yassine Himeur , Hamzah Ali Alkhazaleh , Shadi Atalla , Wathiq Mansoor

Artificial intelligence based radiomics models for thyroid ultrasound (US) often achieve strong diagnostic performance but remain difficult to interpret, limiting clinical trust and adoption. We developed and validated an interpretable…

Computer-aided diagnosis (CAD) is becoming a prominent approach to assist clinicians spanning across multiple fields. These automated systems take advantage of various computer vision (CV) procedures, as well as artificial intelligence (AI)…

Image and Video Processing · Electrical Eng. & Systems 2021-10-26 Danilo Avola , Luigi Cinque , Alessio Fagioli , Sebastiano Filetti , Giorgio Grani , Emanuele Rodolà

Thyroid cancer is currently the fifth most common malignancy diagnosed in women. Since differentiation of cancer sub-types is important for treatment and current, manual methods are time consuming and subjective, automatic computer-aided…

Ultrasound examination is widely used in the clinical diagnosis of thyroid nodules (benign/malignant). However, the accuracy relies heavily on radiologist experience. Although deep learning techniques have been investigated for thyroid…

Computer Vision and Pattern Recognition · Computer Science 2022-07-01 Yuchen Wang , Zhongyu Li , Xiangxiang Cui , Liangliang Zhang , Xiang Luo , Meng Yang , Shi Chang

Accurate detection of thyroid lesions is a critical aspect of computer-aided diagnosis. However, most existing detection methods perform only one feature extraction process and then fuse multi-scale features, which can be affected by noise…

Computer Vision and Pattern Recognition · Computer Science 2023-05-25 Lingtao Wang , Jianrui Ding , Fenghe Tang , Chunping Ning

Thyroid nodule segmentation in ultrasound images is crucial for accurate diagnosis and treatment planning. However, existing methods face challenges in segmentation accuracy, interpretability, and generalization, which hinder their…

Computer Vision and Pattern Recognition · Computer Science 2024-12-10 Xinjie Sun , Boxiong Wei , Yalong Jiang , Liquan Mao , Qi Zhao

Ultrasound is a useful technique for diagnosing thyroid nodules. Benign and malignant nodules that automatically discriminate in the ultrasound pictures can provide diagnostic recommendations or, improve diagnostic accuracy in the absence…

Computer Vision and Pattern Recognition · Computer Science 2024-09-05 Ponugoti Nikhila , Sabari Nathan , Elmer Jeto Gomes Ataide , Alfredo Illanes , Michael Friebe , Srichandana Abbineni

Thyroid disease instances have been continuously increasing since the 1990s, and thyroid cancer has become the most rapidly rising disease among all the malignancies in recent years. Most existing studies focused on applying deep…

Image and Video Processing · Electrical Eng. & Systems 2022-03-09 Xinyu Zhang , Vincent CS. Lee , Jia Rong , James C. Lee , Jiangning Song , Feng Liu

Ultrasound (US) is the primary imaging technique for the diagnosis of thyroid cancer. However, accurate identification of nodule malignancy is a challenging task that can elude less-experienced clinicians. Recently, many computer-aided…

Image and Video Processing · Electrical Eng. & Systems 2022-07-12 Van T. Manh , Jianqiao Zhou , Xiaohong Jia , Zehui Lin , Wenwen Xu , Zihan Mei , Yijie Dong , Xin Yang , Ruobing Huang , Dong Ni

Thyroid nodule classification and segmentation in ultrasound images are crucial for computer-aided diagnosis; however, they face limitations owing to insufficient labeled data. In this study, we proposed a multi-view contrastive…

Computer Vision and Pattern Recognition · Computer Science 2024-02-20 Jian Wang , Xin Yang , Xiaohong Jia , Wufeng Xue , Rusi Chen , Yanlin Chen , Xiliang Zhu , Lian Liu , Yan Cao , Jianqiao Zhou , Dong Ni , Ning Gu

Objectives: The purpose is to apply a previously validated deep learning algorithm to a new thyroid nodule ultrasound image dataset and compare its performances with radiologists. Methods: Prior study presented an algorithm which is able to…

Image and Video Processing · Electrical Eng. & Systems 2023-05-08 Jingxi Weng , Benjamin Wildman-Tobriner , Mateusz Buda , Jichen Yang , Lisa M. Ho , Brian C. Allen , Wendy L. Ehieli , Chad M. Miller , Jikai Zhang , Maciej A. Mazurowski

Purpose: Thyroid cancer has been a common cancer. Papillary thyroid cancer and follicular thyroid cancer are the two most common types of thyroid cancer. Follicular thyroid cancer lacks distinctive ultrasound signs and is more difficult to…

Machine Learning · Computer Science 2025-09-17 Songlin Zhou , Tao Zhou , Xin Li , Stephen Shing-Toung Yau

Thyroid cancer is common worldwide, with a rapid increase in prevalence across North America in recent years. While most patients present with palpable nodules through physical examination, a large number of small and medium-sized nodules…

Image and Video Processing · Electrical Eng. & Systems 2020-06-11 Fatemeh Abdolali , Atefeh Shahroudnejad , Abhilash Rakkunedeth Hareendranathan , Jacob L Jaremko , Michelle Noga , Kumaradevan Punithakumar
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