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Effective postprandial glucose control is important to glucose management for subjects with diabetes mellitus. In this work, a data-driven meal bolus decision method is proposed without the need of subject-specific glucose management…

Systems and Control · Electrical Eng. & Systems 2021-01-21 Deheng Cai , Wei Liu , Linong Ji , Dawei Shi

Type 1 Diabetes (T1D) management requires continuous adjustment of insulin and lifestyle behaviors to maintain blood glucose within a safe target range. Although automated insulin delivery (AID) systems have improved glycemic outcomes, many…

Recommender Systems have not been explored to a great extent for improving health and subjective wellbeing. Recent advances in mobile technologies and user modelling present the opportunity for delivering such systems, however the key issue…

Human-Computer Interaction · Computer Science 2019-09-10 Mohammed Khwaja , Miquel Ferrer , Jesus Omana Iglesias , A. Aldo Faisal , Aleksandar Matic

Despite recent advances in insulin preparations and technology, adjusting insulin remains an ongoing challenge for the majority of people with type 1 diabetes (T1D) and longstanding type 2 diabetes (T2D). In this study, we propose the…

The growing worldwide incidence of diabetes requires more effective approaches for managing blood glucose levels. Insulin delivery systems have advanced significantly, with artificial intelligence (AI) playing a key role in improving their…

Artificial Intelligence · Computer Science 2025-03-25 Maria Panagiotou , Knut Stroemmen , Lorenzo Brigato , Bastiaan E. de Galan , Stavroula Mougiakakou

Gestational diabetes (GDM) poses a growing health risk to both pregnant women and their offspring. While telehealth interventions for GDM management have proven effective, they have traditionally relied on healthcare professionals for…

Human-Computer Interaction · Computer Science 2023-09-20 Mikko Kytö , Saila Koivusalo , Heli Tuomonen , Lisbeth Strömberg , Antti Ruonala , Pekka Marttinen , Seppo Heinonen , Giulio Jacucci

Patients with diabetes who are self-monitoring have to decide right before each meal how much insulin they should take. A standard bolus advisor exists, but has never actually been proven to be optimal in any sense. We challenged this rule…

Machine Learning · Statistics 2020-07-24 Frédéric Logé , Erwan Le Pennec , Habiboulaye Amadou-Boubacar

Sufficient physical activity can prolong the ability of older adults to live inde-pendently. Community-based exercise programs can be enhanced by regularly performing exercises at home. To support such a home-based exercise program, a…

Human-Computer Interaction · Computer Science 2021-01-26 Sumit Mehra , Jantine van den Helder , Ben J. A. Kröse , Raoul H. H. Engelbert , Peter J. M. Weijs , Bart Visser

Insulin resistance, a precursor to type 2 diabetes, is characterized by impaired insulin action in tissues. Current methods for measuring insulin resistance, while effective, are expensive, inaccessible, not widely available and hinder…

People with type 1 diabetes (T1D) lack the ability to produce the insulin their bodies need. As a result, they must continually make decisions about how much insulin to self-administer to adequately control their blood glucose levels.…

Machine Learning · Computer Science 2020-09-22 Ian Fox , Joyce Lee , Rodica Pop-Busui , Jenna Wiens

Diabetes affects over 400 million people and is among the leading causes of morbidity worldwide. Identification of high-risk individuals can support early diagnosis and prevention of disease development through lifestyle changes. However,…

Machine Learning · Computer Science 2021-04-21 Nikola Dolezalova , Massimo Cairo , Alex Despotovic , Adam T. C. Booth , Angus B. Reed , Davide Morelli , David Plans

The human insulin-glucose metabolism is a time-varying process, which is partly caused by the changing insulin sensitivity of the body. This insulin sensitivity follows a circadian rhythm and its effects should be anticipated by any…

Systems and Control · Electrical Eng. & Systems 2021-01-29 Lukas Ortmann , Dawei Shi , Eyal Dassau , Francis J. Doyle , Berno J. E. Misgeld , Steffen Leonhardt

The existing adaptive basal-bolus advisor (ABBA) was further developed to benefit patients under insulin therapy with multiple daily injections (MDI). Three different in silico experiments were conducted with the DMMS.R simulator to…

Tissues and Organs · Quantitative Biology 2019-06-21 Qingnan Sun , Marko V. Jankovic , Stavroula G. Mougiakakou

Type 1 Diabetes is a chronic autoimmune condition in which the immune system attacks and destroys insulin-producing beta cells in the pancreas, resulting in little to no insulin production. Insulin helps glucose in your blood enter your…

Quantitative Methods · Quantitative Biology 2025-02-04 Soon Jynn Chu , Nalaka Amarasiri , Sandesh Giri , Priyata Kafle

Identifying type 2 diabetes mellitus can be challenging, particularly for primary care physicians. Clinical decision support systems incorporating artificial intelligence (AI-CDSS) can assist medical professionals in diagnosing type 2…

Machine Learning · Computer Science 2026-02-13 Mujeeb Ur Rehman , Imran Rehan , Sohail Khalid

Prediabetes is a common health condition that often goes undetected until it progresses to type 2 diabetes. Early identification of prediabetes is essential for timely intervention and prevention of complications. This research explores the…

Signal Processing · Electrical Eng. & Systems 2025-04-08 Dimitra Tatli , Vasileios Papapanagiotou , Aris Liakos , Apostolos Tsapas , Anastasios Delopoulos

To empower users of wearable medical devices, it is important to enable methods that facilitate reflection on previous care to improve future outcomes. In this work, we conducted a two-phase user-study involving patients, caregivers, and…

Computers and Society · Computer Science 2020-07-28 Temiloluwa Prioleau , Ashutosh Sabharwal , Madhuri M. Vasudevan

A task of vital clinical importance, within Diabetes management, is the prevention of hypo/hyperglycemic events. Increasingly adopted Continuous Glucose Monitoring (CGM) devices offer detailed, non-intrusive and real time insights into a…

Machine Learning · Computer Science 2023-03-09 Jakub J. Dylag

The challenge of handling missing data is widespread in modern data analysis, particularly during the preprocessing phase and in various inferential modeling tasks. Although numerous algorithms exist for imputing missing data, the…

Methodology · Statistics 2024-03-28 Marcos Matabuena , Carla Díaz-Louzao , Rahul Ghosal , Francisco Gude

Motivation: There is a growing need to integrate mechanistic models of biological processes with computational methods in healthcare in order to improve prediction. We apply data assimilation in the context of Type 2 diabetes to understand…