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Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized by complex physiological processes. Previous research has predominantly focused on static cerebral interactions, often neglecting the brain's dynamic nature and…

Machine Learning · Computer Science 2024-09-11 Peng Wang , Xin Wen , Ruochen Cao , Chengxin Gao , Yanrong Hao , Rui Cao

Kidney branching morphogenesis has been studied extensively, but the mechanism that defines the branch points is still elusive. Here we obtained a 2D movie of kidney branching morphogenesis in culture to test different models of branching…

Tissues and Organs · Quantitative Biology 2013-07-02 Srivathsan Adivarahan , Denis Menshykau , Odysse Michos , Dagmar Iber

Synapses change on multiple timescales, ranging from milliseconds to minutes, due to a combination of both short- and long-term plasticity. Here we develop an extension of the common Generalized Linear Model to infer both short- and…

Neurons and Cognition · Quantitative Biology 2022-08-15 Ganchao Wei , Ian H. Stevenson

Spatiotemporal graph represents a crucial data structure where the nodes and edges are embedded in a geometric space and can evolve dynamically over time. Nowadays, spatiotemporal graph data is becoming increasingly popular and important,…

Machine Learning · Computer Science 2022-03-02 Yuanqi Du , Xiaojie Guo , Hengning Cao , Yanfang Ye , Liang Zhao

Spiking neurons can perform spatiotemporal feature detection by nonlinear synaptic and dendritic integration of presynaptic spike patterns. Multicompartment models of non-linear dendrites and related neuromorphic circuit designs enable…

Neural and Evolutionary Computing · Computer Science 2021-06-02 Mattias Nilsson , Foteini Liwicki , Fredrik Sandin

Deep generative models for graphs have exhibited promising performance in ever-increasing domains such as design of molecules (i.e, graph of atoms) and structure prediction of proteins (i.e., graph of amino acids). Existing work typically…

Machine Learning · Computer Science 2021-01-21 Wenbin Zhang , Liming Zhang , Dieter Pfoser , Liang Zhao

Anomaly detection in dynamic networks is critical for applications from cybersecurity to industrial monitoring, yet existing methods face challenges in energy efficiency, temporal precision, and adaptability. This paper introduces…

Neural and Evolutionary Computing · Computer Science 2026-05-15 Abdul Joseph Fofanah , Lian Wen , David Chen , Tsungcheng Yao , Kwabena Sarpong

Graphene functionalized with catalytic transition metals offers high-performance gas sensing by coupling graphene's exceptional electronic transport properties with the metal's catalytic activity, yet the atomistic relationships connecting…

Materials Science · Physics 2025-05-29 Akram Ibrahim , Ahmed M. Hafez , Mahmooda Sultana , Can Ataca

Learning temporal interaction networks(TIN) is previously regarded as a coarse-grained multi-sequence prediction problem, ignoring the network topology structure influence. This paper addresses this limitation and a Deep Graph Neural Point…

Machine Learning · Computer Science 2025-08-20 Su Chen , Xiaohua Qi , Xixun Lin , Yanmin Shang , Xiaolin Xu , Yangxi Li

Dynamic graphs capture evolving interactions between entities, such as in social networks, online learning platforms, and crowdsourcing projects. For dynamic graph modeling, dynamic graph neural networks (DGNNs) have emerged as a mainstream…

Machine Learning · Computer Science 2025-03-04 Xingtong Yu , Zhenghao Liu , Xinming Zhang , Yuan Fang

The distinct timescales of synaptic plasticity and neural activity dynamics play an important role in the brain's learning and memory systems. Activity-dependent plasticity reshapes neural circuit architecture, determining spontaneous and…

Neurons and Cognition · Quantitative Biology 2023-06-30 Heather L Cihak , Zachary P Kilpatrick

The human brain can be considered as complex networks, composed of various regions that continuously exchange their information with each other, forming the brain network graph, from which nodes and edges are extracted using resting-state…

Machine Learning · Computer Science 2025-02-19 Parnian Jalali , Mehran Safayani

The central nervous system is composed of many individual units -- from cells to areas -- that are connected with one another in a complex pattern of functional interactions that supports perception, action, and cognition. One natural and…

Neurons and Cognition · Quantitative Biology 2017-04-03 Ann E. Sizemore , Danielle S. Bassett

In neuromorphic computing, artificial synapses provide a multi-weight conductance state that is set based on inputs from neurons, analogous to the brain. Additional properties of the synapse beyond multiple weights can be needed, and can…

Actin cytoskeletal protrusions in crawling cells, or lamellipodia, exhibit various morphological properties such as two characteristic peaks in the distribution of filament orientation with respect to the leading edge. To understand these…

Subcellular Processes · Quantitative Biology 2011-02-23 D. A. Quint , J. M. Schwarz

The exploitation of syntactic graphs (SyGs) as a word's context has been shown to be beneficial for distributional semantic models (DSMs), both at the level of individual word representations and in deriving phrasal representations via…

Computation and Language · Computer Science 2021-06-04 Lorenzo Bertolini , Julie Weeds , David Weir , Qiwei Peng

Deep learning methods have access to be employed for solving physical systems governed by parametric partial differential equations (PDEs) due to massive scientific data. It has been refined to operator learning that focuses on learning…

Machine Learning · Computer Science 2024-03-06 Chu Wang , Jinhong Wu , Yanzhi Wang , Zhijian Zha , Qi Zhou

The actin cortex of an animal cell is a thin polymeric layer attached to the inner side of the plasma membrane. It plays a key role in shape regulation and pattern formation on the cellular and tissue scale and, in particular, generates the…

Biological Physics · Physics 2022-08-24 M. Bonati , L. D. Wittwer , S. Aland , E. Fischer-Friedrich

The initiation of directional cell motion requires symmetry breaking that can happen both with or without external stimuli. During cell crawling, forces generated by the cytoskeleton and their transmission through mechanosensitive adhesions…

Cell Behavior · Quantitative Biology 2023-06-02 Yuzhu Chen , David Saintillan , Padmini Rangamani

Dynamic graphs refer to graphs whose structure dynamically changes over time. Despite the benefits of learning vertex representations (i.e., embeddings) for dynamic graphs, existing works merely view a dynamic graph as a sequence of changes…

Machine Learning · Computer Science 2023-11-02 Yu Yang , Hongzhi Yin , Jiannong Cao , Tong Chen , Quoc Viet Hung Nguyen , Xiaofang Zhou , Lei Chen
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