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The opaque nature of deep learning models remains a significant barrier to their clinical adoption in medical imaging. This paper presents a multimodal explainability framework that bridges the gap between convolutional neural network (CNN)…

Computer Vision and Pattern Recognition · Computer Science 2026-05-08 Paul Valery Nguezet , Elie Tagne Fute , Yusuf Brima , Benoit Martin Azanguezet , Marcellin Atemkeng

When we deploy machine learning models in high-stakes medical settings, we must ensure these models make accurate predictions that are consistent with known medical science. Inherently interpretable networks address this need by explaining…

Computer Vision and Pattern Recognition · Computer Science 2021-10-06 Alina Jade Barnett , Fides Regina Schwartz , Chaofan Tao , Chaofan Chen , Yinhao Ren , Joseph Y. Lo , Cynthia Rudin

Deep neural networks for medical image diagnosis often achieve high predictive accuracy while relying on spurious or clinically irrelevant visual cues, limiting their trustworthiness in practice. Post-hoc explanation methods are widely used…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Zubair Faruqui , Rahul Dubey

Artificial intelligence has become pervasive across disciplines and fields, and biomedical image and signal processing is no exception. The growing and widespread interest on the topic has triggered a vast research activity that is…

Machine Learning · Computer Science 2022-07-12 Guang Yang , Arvind Rao , Christine Fernandez-Maloigne , Vince Calhoun , Gloria Menegaz

Deep learning has been successfully applied to medical image segmentation, enabling accurate identification of regions of interest such as organs and lesions. This approach works effectively across diverse datasets, including those with…

Image and Video Processing · Electrical Eng. & Systems 2025-04-08 Tianyi Ren , Juampablo Heras Rivera , Hitender Oswal , Yutong Pan , Agamdeep Chopra , Jacob Ruzevick , Mehmet Kurt

With an increase in deep learning-based methods, the call for explainability of such methods grows, especially in high-stakes decision making areas such as medical image analysis. This survey presents an overview of eXplainable Artificial…

Image and Video Processing · Electrical Eng. & Systems 2022-05-06 Bas H. M. van der Velden , Hugo J. Kuijf , Kenneth G. A. Gilhuijs , Max A. Viergever

As interpretability has been pointed out as the obstacle to the adoption of Deep Neural Networks (DNNs), there is an increasing interest in solving a transparency issue to guarantee the impressive performance. In this paper, we demonstrate…

Image and Video Processing · Electrical Eng. & Systems 2021-07-20 Woo-Jeoung Nam , Seong-Whan Lee

Deep Learning (DL) holds enormous potential for improving medical imaging diagnostics, yet the lack of interpretability in most models hampers clinical trust and adoption. This paper presents an explainable deep learning framework for…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Sai Teja Erukude , Viswa Chaitanya Marella , Suhasnadh Reddy Veluru

Explainability of AI models is an important topic that can have a significant impact in all domains and applications from autonomous driving to healthcare. The existing approaches to explainable AI (XAI) are mainly limited to simple machine…

Machine Learning · Computer Science 2023-05-24 Poushali Sengupta , Yan Zhang , Sabita Maharjan , Frank Eliassen

Objects, in the real world, rarely occur in isolation and exhibit typical arrangements governed by their independent utility, and their expected interaction with humans and other objects in the context. For example, a chair is expected near…

Computer Vision and Pattern Recognition · Computer Science 2024-11-21 Sharat Agarwal

Recent technological advancements in data acquisition tools allowed life scientists to acquire multimodal data from different biological application domains. Broadly categorized in three types (i.e., sequences, images, and signals), these…

Quantitative Methods · Quantitative Biology 2020-03-03 Mufti Mahmud , M Shamim Kaiser , Amir Hussain

Visual recognition models have achieved unprecedented success in various tasks. While researchers aim to understand the underlying mechanisms of these models, the growing demand for deployment in safety-critical areas like autonomous…

Computer Vision and Pattern Recognition · Computer Science 2026-03-12 Qiyang Wan , Chengzhi Gao , Ruiping Wang , Xilin Chen

Utilizing potent representations of the large vision-language models (VLMs) to accomplish various downstream tasks has attracted increasing attention. Within this research field, soft prompt learning has become a representative approach for…

Computer Vision and Pattern Recognition · Computer Science 2024-03-15 Yequan Bie , Luyang Luo , Zhixuan Chen , Hao Chen

Causal reasoning is the main learning and explanation tool used by humans. AI systems should possess causal reasoning capabilities to be deployed in the real world with trust and reliability. Introducing the ideas of causality to machine…

Machine Learning · Computer Science 2021-06-11 Abbavaram Gowtham Reddy

Deep learning methods have been very effective for a variety of medical diagnostic tasks and has even beaten human experts on some of those. However, the black-box nature of the algorithms has restricted clinical use. Recent explainability…

Computer Vision and Pattern Recognition · Computer Science 2020-05-29 Amitojdeep Singh , Sourya Sengupta , Vasudevan Lakshminarayanan

With the availability of large databases and recent improvements in deep learning methodology, the performance of AI systems is reaching or even exceeding the human level on an increasing number of complex tasks. Impressive examples of this…

Artificial Intelligence · Computer Science 2017-08-29 Wojciech Samek , Thomas Wiegand , Klaus-Robert Müller

A fascinating hypothesis is that human and animal intelligence could be explained by a few principles (rather than an encyclopedic list of heuristics). If that hypothesis was correct, we could more easily both understand our own…

Machine Learning · Computer Science 2022-08-02 Anirudh Goyal , Yoshua Bengio

Causal abstraction is a promising theoretical framework for explainable artificial intelligence that defines when an interpretable high-level causal model is a faithful simplification of a low-level deep learning system. However, existing…

Artificial Intelligence · Computer Science 2024-02-23 Atticus Geiger , Zhengxuan Wu , Christopher Potts , Thomas Icard , Noah D. Goodman

Understanding specifically where a model focuses on within an image is critical for human interpretability of the decision-making process. Deep learning-based solutions are prone to learning coincidental correlations in training datasets,…

Computer Vision and Pattern Recognition · Computer Science 2024-10-22 Aidan Boyd , Mohamed Trabelsi , Huseyin Uzunalioglu , Dan Kushnir

Deep learning (DL) has substantially enhanced natural language processing (NLP) in healthcare research. However, the increasing complexity of DL-based NLP necessitates transparent model interpretability, or at least explainability, for…

Computation and Language · Computer Science 2024-10-17 Guangming Huang , Yingya Li , Shoaib Jameel , Yunfei Long , Giorgos Papanastasiou