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Due to domain shift, deep learning image classifiers perform poorly when applied to a domain different from the training one. For instance, a classifier trained on chest X-ray (CXR) images from one hospital may not generalize to images from…

Image and Video Processing · Electrical Eng. & Systems 2024-08-12 Gianluca Carloni , Sotirios A Tsaftaris , Sara Colantonio

Model explainability is essential for the creation of trustworthy Machine Learning models in healthcare. An ideal explanation resembles the decision-making process of a domain expert and is expressed using concepts or terminology that is…

Machine Learning · Computer Science 2021-07-14 Sumedha Singla , Stephen Wallace , Sofia Triantafillou , Kayhan Batmanghelich

The remarkable success of deep learning has prompted interest in its application to medical imaging diagnosis. Even though state-of-the-art deep learning models have achieved human-level accuracy on the classification of different types of…

Image and Video Processing · Electrical Eng. & Systems 2023-09-20 Cristiano Patrício , João C. Neves , Luís F. Teixeira

Deep neural networks form the backbone of artificial intelligence research, with potential to transform the human experience in areas ranging from autonomous driving to personal assistants, healthcare to education. However, their…

Machine Learning · Computer Science 2025-05-29 Vinitra Swamy

Explainability is a longstanding challenge in deep learning, especially in high-stakes domains like healthcare. Common explainability methods highlight image regions that drive an AI model's decision. Humans, however, heavily rely on…

Artificial Intelligence · Computer Science 2023-11-21 Shobhit Agarwal , Yevgeniy R. Semenov , William Lotter

Deep learning implemented via neural networks, has revolutionized machine learning by providing methods for complex tasks such as object detection/classification and prediction. However, architectures based on deep neural networks have…

Machine Learning · Computer Science 2025-02-11 Nanjangud C. Narendra , Nithin Nagaraj

Deep learning (DL) has recently drawn much attention in image analysis, natural language process, and high-dimensional medical data analysis. Under the causal direct acyclic graph (DAG) interpretation, the input variables without incoming…

Applications · Statistics 2022-03-22 Jong-Hyeon Jeong , Yichen Jia

The Deep learning (DL) models for diagnosing breast cancer from mammographic images often operate as "black boxes", making it difficult for healthcare professionals to trust and understand their decision-making processes. The study presents…

Computer Vision and Pattern Recognition · Computer Science 2024-04-30 Maryam Ahmed , Tooba Bibi , Rizwan Ahmed Khan , Sidra Nasir

In this study, we present an interpretable deep learning framework for the early detection of breast cancer using quantitative features extracted from digitized fine needle aspirate (FNA) images of breast masses. Our deep neural network,…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Bishal Chhetri , B. V. Rathish Kumar

Recent years have seen rapid progress at the intersection between causality and machine learning. Motivated by scientific applications involving high-dimensional data, in particular in biomedicine, we propose a deep neural architecture for…

Machine Learning · Computer Science 2022-12-12 Kai Lagemann , Christian Lagemann , Bernd Taschler , Sach Mukherjee

In the ever-evolving field of Artificial Intelligence, a critical challenge has been to decipher the decision-making processes within the so-called "black boxes" in deep learning. Over recent years, a plethora of methods have emerged,…

Artificial Intelligence · Computer Science 2024-02-15 Karam Dawoud , Wojciech Samek , Peter Eisert , Sebastian Lapuschkin , Sebastian Bosse

The nondeterminism of Deep Learning (DL) training algorithms and its influence on the explainability of neural network (NN) models are investigated in this work with the help of image classification examples. To discuss the issue, two…

Machine Learning · Computer Science 2022-03-03 A. -M. Leventi-Peetz , T. Östreich

There is an increasing interest in the use of Deep Learning (DL) based methods as a supporting analytical framework in oncology. However, most direct applications of DL will deliver models with limited transparency and explainability, which…

Quantitative Methods · Quantitative Biology 2023-01-26 Magdalena Wysocka , Oskar Wysocki , Marie Zufferey , Dónal Landers , André Freitas

Deep neural networks have achieved success across a wide range of applications, including as models of human behavior and neural representations in vision tasks. However, neural network training and human learning differ in fundamental…

Computer Vision and Pattern Recognition · Computer Science 2025-09-04 Lukas Muttenthaler , Klaus Greff , Frieda Born , Bernhard Spitzer , Simon Kornblith , Michael C. Mozer , Klaus-Robert Müller , Thomas Unterthiner , Andrew K. Lampinen

Deep learning (DL) models have been popular due to their ability to learn directly from the raw data in an end-to-end paradigm, alleviating the concern of a separate error-prone feature extraction phase. Recent DL-based neuroimaging studies…

Machine Learning · Computer Science 2023-07-20 Md. Mahfuzur Rahman , Vince D. Calhoun , Sergey M. Plis

Explainability plays a crucial role in providing a more comprehensive understanding of deep learning models' behaviour. This allows for thorough validation of the model's performance, ensuring that its decisions are based on relevant visual…

Machine Learning · Computer Science 2023-06-16 E. Zhixuan Zeng , Hayden Gunraj , Sheldon Fernandez , Alexander Wong

Deep learning shows promise for medical image analysis but lacks interpretability, hindering adoption in healthcare. Attribution techniques that explain model reasoning may increase trust in deep learning among clinical stakeholders. This…

Machine Learning · Computer Science 2023-08-08 Yusuf Brima , Marcellin Atemkeng

Explainable artificial intelligence (XAI) has become increasingly important in biomedical image analysis to promote transparency, trust, and clinical adoption of DL models. While several surveys have reviewed XAI techniques, they often lack…

Computer Vision and Pattern Recognition · Computer Science 2025-07-11 Getamesay Haile Dagnaw , Yanming Zhu , Muhammad Hassan Maqsood , Wencheng Yang , Xingshuai Dong , Xuefei Yin , Alan Wee-Chung Liew

A key issue in critical contexts such as medical diagnosis is the interpretability of the deep learning models adopted in decision-making systems. Research in eXplainable Artificial Intelligence (XAI) is trying to solve this issue. However,…

Computer Vision and Pattern Recognition · Computer Science 2021-11-24 Carlo Metta , Andrea Beretta , Riccardo Guidotti , Yuan Yin , Patrick Gallinari , Salvatore Rinzivillo , Fosca Giannotti

Deep learning models have gained increasing adoption in medical image analysis. However, these models often produce overconfident predictions, which can compromise clinical accuracy and reliability. Bridging the gap between high-performance…

Image and Video Processing · Electrical Eng. & Systems 2026-03-24 Jutika Borah , Hidam Kumarjit Singh
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