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The field of healthcare has increasingly turned its focus towards Large Language Models (LLMs) due to their remarkable performance. However, their performance in actual clinical applications has been underexplored. Traditional evaluations…

The integration of visual inputs with large language models (LLMs) has led to remarkable advancements in multi-modal capabilities, giving rise to visual large language models (VLLMs). However, effectively harnessing VLLMs for intricate…

Computer Vision and Pattern Recognition · Computer Science 2023-11-14 Renjie Pi , Lewei Yao , Jiahui Gao , Jipeng Zhang , Tong Zhang

Large language models (LLMs) have demonstrated remarkable capabilities in natural language understanding and generation across various domains, including medicine. We present a comprehensive evaluation of GPT-4, a state-of-the-art LLM, on…

Computation and Language · Computer Science 2023-04-13 Harsha Nori , Nicholas King , Scott Mayer McKinney , Dean Carignan , Eric Horvitz

With the increasing application of large language models (LLMs) in the medical domain, evaluating these models' performance using benchmark datasets has become crucial. This paper presents a comprehensive survey of various benchmark…

Vision impairment affects millions globally, and early detection is critical to preventing irreversible vision loss. Ophthalmology workflows require clinicians to integrate medical images, structured clinical data, and free-text notes to…

Multimodal large language models (MLLMs) represent an evolutionary expansion in the capabilities of traditional large language models, enabling them to tackle challenges that surpass the scope of purely text-based applications. It leverages…

Computation and Language · Computer Science 2025-01-17 Jinlong He , Pengfei Li , Gang Liu , Genrong He , Zhaolin Chen , Shenjun Zhong

Automatic disease diagnosis has become increasingly valuable in clinical practice. The advent of large language models (LLMs) has catalyzed a paradigm shift in artificial intelligence, with growing evidence supporting the efficacy of LLMs…

Current Large Language Models (LLMs) exhibit significant limitations, notably in structured, interpretable, and verifiable medical reasoning, alongside practical deployment challenges related to computational resources and data privacy.…

Computation and Language · Computer Science 2025-06-06 Boqin Zhuang , Chenxiao Song , Huitong Lu , Jiacheng Qiao , Mingqian Liu , Mingxing Yu , Ping Hong , Rui Li , Xiaoxia Song , Xiangjun Xu , Xu Chen , Yaoyao Ma , Yujie Gao

Recent researches of large language models(LLM), which is pre-trained on massive general-purpose corpora, have achieved breakthroughs in responding human queries. However, these methods face challenges including limited data insufficiency…

Computation and Language · Computer Science 2025-01-07 Yiming Zhang , Zheng Chang , Wentao Cai , MengXing Ren , Kang Yuan , Yining Sun , Zenghui Ding

Accurate and interpretable multi-disease diagnosis remains a critical challenge in medical research, particularly when leveraging heterogeneous multimodal medical data. Current approaches often rely on single-modal data, limiting their…

Image and Video Processing · Electrical Eng. & Systems 2025-06-25 Yuting Zhang , Kaishen Yuan , Hao Lu , Yutao Yue , Jintai Chen , Kaishun Wu

Multi-modal Large Language Models (MLLMs) have advanced greatly in general tasks. However, they still face challenges in geometric reasoning, a task that requires synergistic integration of visual recognition proficiency and complex…

Computer Vision and Pattern Recognition · Computer Science 2026-02-10 Zhihao Li , Yao Du , Yang Liu , Yan Zhang , Yufang Liu , Mengdi Zhang , Xunliang Cai , Charles Ling , Boyu Wang

Natural language is a powerful complementary modality of communication for data visualizations, such as bar and line charts. To facilitate chart-based reasoning using natural language, various downstream tasks have been introduced recently…

Computation and Language · Computer Science 2024-10-07 Mohammed Saidul Islam , Raian Rahman , Ahmed Masry , Md Tahmid Rahman Laskar , Mir Tafseer Nayeem , Enamul Hoque

With the rapid development of artificial intelligence, large language models (LLMs) have shown promising capabilities in mimicking human-level language comprehension and reasoning. This has sparked significant interest in applying LLMs to…

Computation and Language · Computer Science 2023-11-06 Mingze Yuan , Peng Bao , Jiajia Yuan , Yunhao Shen , Zifan Chen , Yi Xie , Jie Zhao , Yang Chen , Li Zhang , Lin Shen , Bin Dong

Instruction tuning has significantly advanced large language models (LLMs) such as ChatGPT, enabling them to align with human instructions across diverse tasks. However, progress in open vision-language models (VLMs) has been limited due to…

Computer Vision and Pattern Recognition · Computer Science 2023-06-09 Lei Li , Yuwei Yin , Shicheng Li , Liang Chen , Peiyi Wang , Shuhuai Ren , Mukai Li , Yazheng Yang , Jingjing Xu , Xu Sun , Lingpeng Kong , Qi Liu

With the rapid advancement of deep learning, particularly in the field of medical image analysis, an increasing number of Vision-Language Models (VLMs) are being widely applied to solve complex health and biomedical challenges. However,…

Computer Vision and Pattern Recognition · Computer Science 2025-03-21 Haiyang Yu , Siyang Yi , Ke Niu , Minghan Zhuo , Bin Li

Large language models (LLMs) show promise in medical diagnosis, but real-world deployment remains challenging due to high-stakes clinical decisions and imperfect reasoning reliability. As a result, careful inspection of model behavior is…

Computation and Language · Computer Science 2026-04-28 Yurui Xiang , Xingyi Mao , Rui Sheng , Zixin Chen , Zelin Zang , Yuyang Wu , Haipeng Zeng , Huamin Qu , Yushi Sun , Yanna Lin

The significant advancements in visual understanding and instruction following from Multimodal Large Language Models (MLLMs) have opened up more possibilities for broader applications in diverse and universal human-centric scenarios.…

Computer Vision and Pattern Recognition · Computer Science 2024-10-10 Keliang Li , Zaifei Yang , Jiahe Zhao , Hongze Shen , Ruibing Hou , Hong Chang , Shiguang Shan , Xilin Chen

Despite the promising results of large multimodal models (LMMs) in complex vision-language tasks that require knowledge, reasoning, and perception abilities together, we surprisingly found that these models struggle with simple tasks on…

Graphics · Computer Science 2025-03-17 Kai Zhang , Jianwei Yang , Jeevana Priya Inala , Chandan Singh , Jianfeng Gao , Yu Su , Chenglong Wang

Specialized clinical AI assistants are rapidly entering medical practice, often framed as safer or more reliable than general-purpose large language models (LLMs). Yet, unlike frontier models, these clinical tools are rarely subjected to…

Computation and Language · Computer Science 2025-12-02 Krithik Vishwanath , Mrigayu Ghosh , Anton Alyakin , Daniel Alexander Alber , Yindalon Aphinyanaphongs , Eric Karl Oermann

As the development of Large Models (LMs) progresses rapidly, their safety is also a priority. In current Large Language Models (LLMs) and Multimodal Large Language Models (MLLMs) safety workflow, evaluation, diagnosis, and alignment are…

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