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A major challenge in computed tomography (CT) is how to minimize patient radiation exposure without compromising image quality and diagnostic performance. The use of deep convolutional (Conv) neural networks for noise reduction in Low-Dose…

Computer Vision and Pattern Recognition · Computer Science 2019-08-06 Chenyu You , Linfeng Yang , Yi Zhang , Ge Wang

The acquisition conditions for low-dose and high-dose CT images are usually different, so that the shifts in the CT numbers often occur. Accordingly, unsupervised deep learning-based approaches, which learn the target image distribution,…

Image and Video Processing · Electrical Eng. & Systems 2022-07-15 Chanyong Jung , Joonhyung Lee , Sunkyoung You , Jong Chul Ye

Denoising low-dose computed tomography (CT) images is a critical task in medical image computing. Supervised deep learning-based approaches have made significant advancements in this area in recent years. However, these methods typically…

Image and Video Processing · Electrical Eng. & Systems 2023-07-17 Xuan Liu , Yaoqin Xie , Jun Cheng , Songhui Diao , Shan Tan , Xiaokun Liang

Deep learning has achieved notable performance in the denoising task of low-quality medical images and the detection task of lesions, respectively. However, existing low-quality medical image denoising approaches are disconnected from the…

Computer Vision and Pattern Recognition · Computer Science 2021-04-20 Kecheng Chen , Kun Long , Yazhou Ren , Jiayu Sun , Xiaorong Pu

Low-dose computed tomography (CT) denoising is crucial for reduced radiation exposure while ensuring diagnostically acceptable image quality. Despite significant advancements driven by deep learning (DL) in recent years, existing DL-based…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Zhihao Chen , Qi Gao , Zilong Li , Junping Zhang , Yi Zhang , Jun Zhao , Hongming Shan

Noise is ubiquitous during image acquisition. Sufficient denoising is often an important first step for image processing. In recent decades, deep neural networks (DNNs) have been widely used for image denoising. Most DNN-based image…

Computer Vision and Pattern Recognition · Computer Science 2024-08-02 Chenyin Gao , Shu Yang , Anru R. Zhang

Real noisy-clean pairs on a large scale are costly and difficult to obtain. Meanwhile, supervised denoisers trained on synthetic data perform poorly in practice. Self-supervised denoisers, which learn only from single noisy images, solve…

Image and Video Processing · Electrical Eng. & Systems 2023-05-09 Zejin Wang , Jiazheng Liu , Guoqing Li , Hua Han

Fluorescence microscopy image (FMI) denoising faces critical challenges due to the compound mixed Poisson-Gaussian noise with strong spatial correlation and the impracticality of acquiring paired noisy/clean data in dynamic biomedical…

Image and Video Processing · Electrical Eng. & Systems 2025-09-25 Jizhihui Liu , Qixun Teng , Qing Ma , Junjun Jiang

Medical image acquisition is often intervented by unwanted noise that corrupts the information content. This paper introduces an unsupervised medical image denoising technique that learns noise characteristics from the available images and…

Image and Video Processing · Electrical Eng. & Systems 2021-03-12 Swati Rai , Jignesh S. Bhatt , S. K. Patra

Deep-learning methods have shown promising performance for low-dose computed tomography (LDCT) reconstruction. However, supervised methods face the problem of lacking labeled data in clinical scenarios, and the CNN-based unsupervised…

Image and Video Processing · Electrical Eng. & Systems 2025-04-25 Ran An , Ke Chen , Hongwei Li

This paper proposes a deep learning-based denoising method for noisy low-dose computerized tomography (CT) images in the absence of paired training data. The proposed method uses a fidelity-embedded generative adversarial network (GAN) to…

Computer Vision and Pattern Recognition · Computer Science 2019-08-13 Hyoung Suk Park , Jineon Baek , Sun Kyoung You , Jae Kyu Choi , Jin Keun Seo

Low dose computed tomography (LDCT) has attracted more and more attention in routine clinical diagnosis assessment, therapy planning, etc., which can reduce the dose of X-ray radiation to patients. However, the noise caused by low X-ray…

Image and Video Processing · Electrical Eng. & Systems 2021-07-06 Zhicheng Zhang , Lequan Yu , Xiaokun Liang , Wei Zhao , Lei Xing

Increasing use of CT in modern medical practice has raised concerns over associated radiation dose. Reduction of radiation dose associated with CT can increase noise and artifacts, which can adversely affect diagnostic confidence. Denoising…

Computer Vision and Pattern Recognition · Computer Science 2017-02-24 Qingsong Yang , Pingkun Yan , Mannudeep K. Kalra , Ge Wang

Recently, denoising methods based on supervised learning have exhibited promising performance. However, their reliance on external datasets containing noisy-clean image pairs restricts their applicability. To address this limitation,…

Computer Vision and Pattern Recognition · Computer Science 2023-07-21 Jaekyun Ko , Sanghwan Lee

Propagation-based X-ray phase-contrast imaging (PBI) enables high-contrast visualization of lung structures and holds strong medical potential. However, safe translation to the clinic will require a substantial radiation dose reduction,…

Light field microscopy (LFM) has gained significant attention due to its ability to capture snapshot-based, large-scale 3D fluorescence images. However, existing LFM reconstruction algorithms are highly sensitive to sensor noise or require…

Computer Vision and Pattern Recognition · Computer Science 2026-05-27 Jiayin Zhao , Zhenqi Fu , Tao Yu , Hui Qiao

Noise removal of images is an essential preprocessing procedure for many computer vision tasks. Currently, many denoising models based on deep neural networks can perform well in removing the noise with known distributions (i.e. the…

Computer Vision and Pattern Recognition · Computer Science 2023-06-21 Wencong Wu , Guannan Lv , Yingying Duan , Peng Liang , Yungang Zhang , Yuelong Xia

Recently, there has been extensive research interest in training deep networks to denoise images without clean reference. However, the representative approaches such as Noise2Noise, Noise2Void, Stein's unbiased risk estimator (SURE), etc.…

Image and Video Processing · Electrical Eng. & Systems 2021-10-28 Kwanyoung Kim , Jong Chul Ye

Unlike single image task, stereo image enhancement can use another view information, and its key stage is how to perform cross-view feature interaction to extract useful information from another view. However, complex noise in low-light…

Computer Vision and Pattern Recognition · Computer Science 2024-01-17 Minghua Zhao , Xiangdong Qin , Shuangli Du , Xuefei Bai , Jiahao Lyu , Yiguang Liu

Deep neural networks have shown great success in low dose CT denoising. However, most of these deep neural networks have several hundred thousand trainable parameters. This, combined with the inherent non-linearity of the neural network,…

Image and Video Processing · Electrical Eng. & Systems 2020-10-12 Mayank Patwari , Ralf Gutjahr , Rainer Raupach , Andreas Maier