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Objective: We hypothesized that prenatal stress (PS) exerts lasting impact on fetal heart rate (fHR). We sought to validate the presence of such PS signature in fHR by measuring coupling between maternal HR (mHR) and fHR. Study design:…

Obstructive sleep apnea (OSA) is believed to contribute significantly to atrial fibrillation (AF) development in certain patients. Recent studies indicate a rising risk of AF with increasing OSA severity. However, the commonly used…

The monitoring of fetal heart rate (FHR) and the assessment of its variability are crucial for preventing fetal compromise and adverse outcomes. However, traditional methods encounter limitations arising from equipment performance, data…

Machine Learning · Computer Science 2026-05-15 Xiaohua Wang , Kai Yu , XuXiao Liang , Liang Wang , Chao Han

Objective: The aim of the study is to develop a novel method for improved diagnosis of obstructive sleep apnea-hypopnea syndrome (OSAHS) in clinical or home settings, with the focus on achieving diagnostic performance comparable to the…

Signal Processing · Electrical Eng. & Systems 2025-01-28 Wei Wang , Zhaoxi Chen , Wenyu Zhang , Zetao Wang , Xiang Zhao , Chenyang Li , Jian Guan , Shankai Yin , Gang Li

Obstructive Sleep Apnea-Hypopnea Syndrome (OSAHS) is a sleep-related breathing disorder associated with significant morbidity and mortality worldwide. The gold standard for OSAHS diagnosis, polysomnography (PSG), faces challenges in…

Signal Processing · Electrical Eng. & Systems 2025-04-28 Wei Wang , Chenyang Li , Zhaoxi Chen , Wenyu Zhang , Zetao Wang , Xi Guo , Jian Guan , Gang Li

Fetal heart rate variability (fHRV) is an important indicator of health and disease, yet its physiological origins, neural contributions in particular, are not well understood. We aimed to develop novel experimental and data analytical…

Prenatal maternal stress (PS) is a risk factor for adverse offspring neurodevelopment. Heart rate variability (HRV) complexity provides a non-invasive marker of maternal autonomic regulation and may be influenced by mind--body interventions…

Quantitative Methods · Quantitative Biology 2025-10-28 Marlene J E Mayer , Nicolas B Garnier , Clara Becker , Marta C Antonelli , Silvia M Lobmaier , Martin G Frasch

Obstructive sleep apnea (OSA) is one of the most widespread respiratory diseases today. Complete or relative breathing cessations due to upper airway subsidence during sleep is OSA. It has confirmed potential influence on Covid-19…

Machine Learning · Computer Science 2021-12-20 Hosna Ghandeharioun

A database of fetal heart rate (FHR) time series measured from 7221 patients during labor is analyzed with the aim of learning the types of features of these recordings that are informative of low cord pH. Our 'highly comparative' analysis…

Machine Learning · Computer Science 2014-12-04 B. D. Fulcher , A. E. Georgieva , C. W. G. Redman , Nick S. Jones

Obstructive sleep apnoea (OSA) is a prevalent condition with significant health consequences, yet many patients remain undiagnosed due to the complexity and cost of over-night polysomnography. Acoustic-based screening provides a scalable…

Sound · Computer Science 2026-02-03 Xiaolei Xu , Chaoyue Niu , Guy J. Brown , Hector Romero , Ning Ma

Fetal oxygen delivery and consumption and blood gases in relation to gestational age. Oxygen crosses the placenta by diffusion and placental permeability to O$_2$ is high. Thus, the fetus receives adequate amounts, but vascular Po$_2$ is…

Other Quantitative Biology · Quantitative Biology 2021-09-27 D. W. Rurak , M. Y. Shen , K. S. Joseph

Chronic fetal hypoxia and infection are examples of adverse conditions during complicated pregnancy, which impact cardiac myogenesis and increase the lifetime risk of heart disease. However, the effects that chronic hypoxic or inflammatory…

Cell Behavior · Quantitative Biology 2020-03-23 Martin G. Frasch , Dino A. Giussani

Obstructive sleep apnea-hypopnea syndrome (OSAHS) is a common sleep disorder caused by upper airway blockage, leading to oxygen deprivation and disrupted sleep. Traditional diagnosis using polysomnography (PSG) is expensive, time-consuming,…

Computer Vision and Pattern Recognition · Computer Science 2024-12-30 Yingchen Wei , Xihe Qiu , Xiaoyu Tan , Jingjing Huang , Wei Chu , Yinghui Xu , Yuan Qi

Transitions in the dynamics of complex systems can be characterized by changes in the synchronization behavior of their components. Taking the human cardio-respiratory system as an example and using an automated procedure for screening the…

Data Analysis, Statistics and Probability · Physics 2009-11-13 Ronny Bartsch , Jan W. Kantelhardt , Thomas Penzel , Shlomo Havlin

Obstructive sleep apnea (OSA) is a common sleep disorder caused by abnormal breathing. The severity of OSA can lead to many symptoms such as sudden cardiac death (SCD). Polysomnography (PSG) is a gold standard for OSA diagnosis. It records…

Signal Processing · Electrical Eng. & Systems 2020-07-28 Nannapas Banluesombatkul , Thanawin Rakthanmanon , Theerawit Wilaiprasitporn

Obstructive Sleep Apnea Syndrome (OSAS) is the most common sleep-related breathing disorder. It is caused by an increased upper airway resistance during sleep, which determines episodes of partial or complete interruption of airflow. The…

Machine Learning · Computer Science 2023-02-13 Andrea Bernardini , Andrea Brunello , Gian Luigi Gigli , Angelo Montanari , Nicola Saccomanno

Obstructive sleep Apnea (OSA) is a form of sleep disordered breathing characterized by frequent episodes of upper airway collapse during sleep. Pediatric OSA occurs in 1-5% of children and can related to other serious health conditions such…

Quantitative Methods · Quantitative Biology 2020-02-20 Sarah Tymochko , Kritika Singhal , Giseon Heo

Approximately 10\% of newborns require assistance to initiate breathing at birth, and around 5\% need ventilation support. Fetal heart rate (FHR) monitoring plays a crucial role in assessing fetal well-being during prenatal care, enabling…

Machine Learning · Computer Science 2025-09-26 Kjersti Engan , Neel Kanwal , Anita Yeconia , Ladislaus Blacy , Yuda Munyaw , Estomih Mduma , Hege Ersdal

Approximately 10% of newborns require assistance to initiate breathing at birth, and around 5% need ventilation support. Fetal heart rate (FHR) monitoring plays a crucial role in assessing fetal well-being during prenatal care, enabling the…

Artificial Intelligence · Computer Science 2026-05-29 Kjersti Engan , Neel Kanwal , Anita Yeconia , Ladislaus Blacy , Yuda Munyaw , Estomih Mduma , Hege Ersdal

Premature births can lead to complications, with fetal lung immaturity being a primary concern. Currently, fetal lung maturity (FLM) requires an invasive surfactant extraction procedure between the 32nd and 39th weeks of pregnancy.…

Medical Physics · Physics 2023-07-21 Márton Á. Goda , Ron Beloosesky , Chen Ben David , Zeev Weiner , Joachim A. Behar
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