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To understand dynamic developmental processes, living tissues must be imaged frequently and for extended periods of time. Root development is extensively studied at cellular resolution to understand basic mechanisms underlying pattern…

Tissues and Organs · Quantitative Biology 2015-03-13 Giovanni Sena , Zak Frentz , Kenneth D. Birnbaum , Stanislas Leibler

Tracking of plant cells in images obtained by microscope is a challenging problem due to biological phenomena such as large number of cells, non-uniform growth of different layers of the tightly packed plant cells and cell division.…

Computer Vision and Pattern Recognition · Computer Science 2023-09-22 Md Shazid Islam , Arindam Dutta , Calvin-Khang Ta , Kevin Rodriguez , Christian Michael , Mark Alber , G. Venugopala Reddy , Amit K. Roy-Chowdhury

Accurate segmentation of 3-D cell nuclei in microscopy images is essential for the study of nuclear organization, gene expression, and cell morphodynamics. Current image segmentation methods are challenged by the complexity and variability…

Image and Video Processing · Electrical Eng. & Systems 2022-03-18 Sundaresh Ram , Jeffrey J. Rodriguez

Cell tracking is an essential tool in live-cell imaging to determine single-cell features, such as division patterns or elongation rates. Unlike in common multiple object tracking, in microbial live-cell experiments cells are growing,…

Computer Vision and Pattern Recognition · Computer Science 2023-03-20 Karina Ruzaeva , Jan-Christopher Cohrs , Keitaro Kasahara , Dietrich Kohlheyer , Katharina Nöh , Benjamin Berkels

Cell detection and tracking are paramount for bio-analysis. Recent approaches rely on the tracking-by-model evolution paradigm, which usually consists of training end-to-end deep learning models to detect and track the cells on the frames…

Computer Vision and Pattern Recognition · Computer Science 2023-10-12 Lucas N. Kirsten , Cláudio R. Jung

This paper presents a method for time-lapse 3D cell analysis. Specifically, we consider the problem of accurately localizing and quantitatively analyzing sub-cellular features, and for tracking individual cells from time-lapse 3D confocal…

Computer Vision and Pattern Recognition · Computer Science 2022-08-18 Jiaxiang Jiang , Amil Khan , S. Shailja , Samuel A. Belteton , Michael Goebel , Daniel B. Szymanski , B. S. Manjunath

The accurate tracking of live cells using video microscopy recordings remains a challenging task for popular state-of-the-art image processing based object tracking methods. In recent years, several existing and new applications have…

Image and Video Processing · Electrical Eng. & Systems 2025-02-03 Gergely Szabó , Paolo Bonaiuti , Andrea Ciliberto , András Horváth

A major challenge in plant developmental biology is to understand how plant growth is coordinated by interacting hormones and genes. To meet this challenge, it is important to not only use experimental data, but also formulate a…

Applications · Statistics 2019-10-22 Samuel E. Jackson , Ian Vernon , Junli Liu , Keith Lindsey

Arabidopsis thaliana is a plant species widely utilized by scientists to estimate the impact of genetic differences in root morphological features. For this purpose, images of this plant after genetic modifications are taken to study…

Computer Vision and Pattern Recognition · Computer Science 2017-04-26 José Ignacio Orlando , Hugo Luis Manterola , Enzo Ferrante , Federico Ariel

In this work, we describe a method for large-scale 3D cell-tracking through a segmentation selection approach. The proposed method is effective at tracking cells across large microscopy datasets on two fronts: (i) It can solve problems…

Computer Vision and Pattern Recognition · Computer Science 2024-04-15 Jordão Bragantini , Merlin Lange , Loïc Royer

One of the challenging problems in biology is to classify plants based on their reaction on genetic mutation. Arabidopsis Thaliana is a plant that is so interesting, because its genetic structure has some similarities with that of human…

Machine Learning · Computer Science 2015-09-07 Hamidreza Farhidzadeh

Microscopy imaging plays a vital role in understanding many biological processes in development and disease. The recent advances in automation of microscopes and development of methods and markers for live cell imaging has led to rapid…

Computer Vision and Pattern Recognition · Computer Science 2017-05-10 Saad Ullah Akram , Juho Kannala , Lauri Eklund , Janne Heikkilä

The presented algorithms for segmentation and tracking follow a 3-step approach where we detect, track and finally segment nuclei. In the preprocessing phase, we detect centroids of the cell nuclei using a convolutional neural network (CNN)…

Computer Vision and Pattern Recognition · Computer Science 2019-04-16 Dennis Eschweiler , Johannes Stegmaier

3D cell tracking in a living organism has a crucial role in live cell image analysis. Cell tracking in C. elegans has two difficulties. First, cell migration in a consecutive frame is large since they move their head during scanning.…

Computer Vision and Pattern Recognition · Computer Science 2024-03-21 Kaito Shiku , Hiromitsu Shirai , Takeshi Ishihara , Ryoma Bise

In recent years, there has been an increasing interest in image-based plant phenotyping, applying state-of-the-art machine learning approaches to tackle challenging problems, such as leaf segmentation (a multi-instance problem) and…

Computer Vision and Pattern Recognition · Computer Science 2017-09-05 Mario Valerio Giuffrida , Hanno Scharr , Sotirios A Tsaftaris

Cell tracking is a ubiquitous image analysis task in live-cell microscopy. Unlike multiple object tracking (MOT) for natural images, cell tracking typically involves hundreds of similar-looking objects that can divide in each frame, making…

Computer Vision and Pattern Recognition · Computer Science 2024-07-25 Benjamin Gallusser , Martin Weigert

Cell tracking algorithms which automate and systematise the analysis of time lapse image data sets of cells are an indispensable tool in the modelling and understanding of cellular phenomena. In this study we present a theoretical framework…

Understanding which genes control which traits in an organism remains one of the central challenges in biology. Despite significant advances in data collection technology, our ability to map genes to traits is still limited. This…

Genomics · Quantitative Biology 2025-08-22 Manuel Serna-Aguilera , Fiona L. Goggin , Aranyak Goswami , Alexander Bucksch , Suxing Liu , Khoa Luu

Cell tracking and segmentation assist biologists in extracting insights from large-scale microscopy time-lapse data. Driven by local accuracy metrics, current tracking approaches often suffer from a lack of long-term consistency and the…

Computer Vision and Pattern Recognition · Computer Science 2025-06-30 Timo Kaiser , Maximilian Schier , Bodo Rosenhahn

Determining the trajectories of cells and their lineages or ancestries in live-cell experiments are fundamental to the understanding of how cells behave and divide. This paper proposes novel online algorithms for jointly tracking and…

Signal Processing · Electrical Eng. & Systems 2021-10-29 Tran Thien Dat Nguyen , Ba-Ngu Vo , Ba-Tuong Vo , Du Yong Kim , Yu Suk Choi
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