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Understanding how cellular morphology, gene expression, and spatial context jointly shape tissue function is a central challenge in biology. Image-based spatial transcriptomics technologies now provide high-resolution measurements of cell…

Quantitative Methods · Quantitative Biology 2026-02-17 Zhenglun Kong , Mufan Qiu , John Boesen , Xiang Lin , Sukwon Yun , Tianlong Chen , Manolis Kellis , Marinka Zitnik

A radiology report comprises several sections, including the Findings and Impression of the diagnosis. Automatically generating the Impression from the Findings is crucial for reducing radiologists' workload and improving diagnostic…

Phenotypic drug discovery has attracted widespread attention because of its potential to identify bioactive molecules. Transcriptomic profiling provides a comprehensive reflection of phenotypic changes in cellular responses to external…

Machine Learning · Computer Science 2025-01-16 Hui Liu , Shikai Jin

Breast tumor segmentation provides accurate tumor boundary, and serves as a key step toward further cancer quantification. Although deep learning-based approaches have been proposed and achieved promising results, existing approaches have…

Image and Video Processing · Electrical Eng. & Systems 2020-02-05 Bryar Shareef , Min Xian , Aleksandar Vakanski

EEG-based emotion recognition plays an important role in developing adaptive brain-computer communication systems, yet faces two fundamental challenges in practical implementations: (1) effective integration of non-stationary…

Machine Learning · Computer Science 2025-08-20 Xuetao Lin , Tianhao Peng , Peihong Dai , Yu Liang , Wenjun Wu

Supervised learning models are typically trained on a single dataset and the performance of these models rely heavily on the size of the dataset, i.e., amount of data available with the ground truth. Learning algorithms try to generalize…

Computation and Language · Computer Science 2018-02-19 Somnath Basu Roy Chowdhury , K M Annervaz , Ambedkar Dukkipati

With the rapid advancement of Spatial Resolved Transcriptomics (SRT) technology, it is now possible to comprehensively measure gene transcription while preserving the spatial context of tissues. Spatial domain identification and gene…

Genomics · Quantitative Biology 2024-08-14 Donghai Fang , Fangfang Zhu , Dongting Xie , Wenwen Min

Mammography stands as the main screening method for detecting breast cancer early, enhancing treatment success rates. The segmentation of landmark structures in mammography images can aid the medical assessment in the evaluation of cancer…

Image and Video Processing · Electrical Eng. & Systems 2025-03-31 Jan Hurtado , Joao P. Maia , Cesar A. Sierra-Franco , Alberto Raposo

High-dimensional data in modern applications, such as COVID-19 mortality, often span multiple domains. Leveraging auxiliary information from source domains to improve performance in a target domain motivates the use of transfer learning.…

Methodology · Statistics 2026-04-09 Haoming Shi , Yang Feng , Xiaoqian Liu

Breast cancer remains a critical global health challenge, necessitating early and accurate detection for effective treatment. This paper introduces a methodology that combines automated image augmentation selection (RandAugment) with search…

Image and Video Processing · Electrical Eng. & Systems 2023-11-21 Leon Hamnett , Mary Adewunmi , Modinat Abayomi , Kayode Raheem , Fahad Ahmed

Medical vision-language pre-training methods mainly leverage the correspondence between paired medical images and radiological reports. Although multi-view spatial images and temporal sequences of image-report pairs are available in…

Artificial Intelligence · Computer Science 2024-05-31 Jinxia Yang , Bing Su , Wayne Xin Zhao , Ji-Rong Wen

Unsupervised learning aims at the discovery of hidden structure that drives the observations in the real world. It is essential for success in modern machine learning. Latent variable models are versatile in unsupervised learning and have…

Machine Learning · Computer Science 2016-06-13 Furong Huang

Transfer learning is a powerful paradigm for leveraging knowledge from source domains to enhance learning in a target domain. However, traditional transfer learning approaches often focus on scalar or multivariate data within Euclidean…

Machine Learning · Computer Science 2025-10-24 Kaicheng Zhang , Sinian Zhang , Doudou Zhou , Yidong Zhou

Hyperspectral image (HSI) denoising is a crucial preprocessing procedure for the subsequent HSI applications. Unfortunately, though witnessing the development of deep learning in HSI denoising area, existing convolution-based methods face…

Computer Vision and Pattern Recognition · Computer Science 2022-11-28 Miaoyu Li , Ying Fu , Yulun Zhang

Transfer learning refers to the process of adapting a model trained on a source task to a target task. While kernel methods are conceptually and computationally simple machine learning models that are competitive on a variety of tasks, it…

Machine Learning · Computer Science 2022-11-02 Adityanarayanan Radhakrishnan , Max Ruiz Luyten , Neha Prasad , Caroline Uhler

With the emergence of advanced spatial transcriptomic technologies, there has been a surge in research papers dedicated to analyzing spatial transcriptomics data, resulting in significant contributions to our understanding of biology. The…

Genomics · Quantitative Biology 2024-04-11 Sikta Das Adhikari , Jiaxin Yang , Jianrong Wang , Yuehua Cui

Identifying disease-indicative genes is critical for deciphering disease mechanisms and has attracted significant interest in biomedical research. Spatial transcriptomics offers unprecedented insights for the detection of disease-specific…

Methodology · Statistics 2024-09-05 Qicheng Zhao , Qihuang Zhang

AI-assisted nuclei segmentation in histopathological images is a crucial task in the diagnosis and treatment of cancer diseases. It decreases the time required to manually screen microscopic tissue images and can resolve the conflict…

Image and Video Processing · Electrical Eng. & Systems 2023-11-21 Hesham Ali , Idriss Tondji , Mennatullah Siam

Multivariate time series classification is of great importance in practical applications and is a challenging task. However, deep neural network models such as Transformers exhibit high accuracy in multivariate time series classification…

Machine Learning · Computer Science 2024-11-19 Mingsen Du , Yanxuan Wei , Yingxia Tang , Xiangwei Zheng , Shoushui Wei , Cun Ji

Accurate spatio-temporal prediction is crucial for the sustainable development of smart cities. However, current approaches often struggle to capture important spatio-temporal relationships, particularly overlooking global relations among…

Machine Learning · Computer Science 2024-11-12 Ashutosh Sao , Simon Gottschalk
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