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Generative modeling of single-cell RNA-seq data is crucial for tasks like trajectory inference, batch effect removal, and simulation of realistic cellular data. However, recent deep generative models simulating synthetic single cells from…

Quantitative Methods · Quantitative Biology 2025-03-04 Alessandro Palma , Till Richter , Hanyi Zhang , Manuel Lubetzki , Alexander Tong , Andrea Dittadi , Fabian Theis

We propose a segmentation framework that uses deep neural networks and introduce two innovations. First, we describe a biophysics-based domain adaptation method. Second, we propose an automatic method to segment white and gray matter, and…

Computer Vision and Pattern Recognition · Computer Science 2018-10-16 Amir Gholami , Shashank Subramanian , Varun Shenoy , Naveen Himthani , Xiangyu Yue , Sicheng Zhao , Peter Jin , George Biros , Kurt Keutzer

The brain white matter consists of a set of tracts that connect distinct regions of the brain. Segmentation of these tracts is often needed for clinical and research studies. Diffusion-weighted MRI offers unique contrast to delineate these…

Image and Video Processing · Electrical Eng. & Systems 2023-07-06 Hamza Kebiri , Ali Gholipour , Meritxell Bach Cuadra , Davood Karimi

Magnetic Resonance Imaging (MRI) of the fetal brain has become a key tool for studying brain development in vivo. Yet, its assessment remains challenging due to variability in brain maturation, imaging protocols, and uncertain estimates of…

Image and Video Processing · Electrical Eng. & Systems 2025-10-09 Johannes Tischer , Patric Kienast , Marlene Stümpflen , Gregor Kasprian , Georg Langs , Roxane Licandro

Deep generative models (DGMs) are effective on learning multilayered representations of complex data and performing inference of input data by exploring the generative ability. However, it is relatively insufficient to empower the…

Computer Vision and Pattern Recognition · Computer Science 2016-11-23 Chongxuan Li , Jun Zhu , Bo Zhang

Functional magnetic resonance imaging (fMRI) is widely used for studying and diagnosing brain disorders, with functional connectivity (FC) matrices providing powerful representations of large-scale neural interactions. However, existing…

Tissues and Organs · Quantitative Biology 2026-04-17 Qianyu Chen , Shujian Yu

The generative priors of pre-trained latent diffusion models (DMs) have demonstrated great potential to enhance the visual quality of image super-resolution (SR) results. However, the noise sampling process in DMs introduces randomness in…

Image and Video Processing · Electrical Eng. & Systems 2024-09-26 Lingchen Sun , Rongyuan Wu , Jie Liang , Zhengqiang Zhang , Hongwei Yong , Lei Zhang

Memory units have been widely used to enrich the capabilities of deep networks on capturing long-term dependencies in reasoning and prediction tasks, but little investigation exists on deep generative models (DGMs) which are good at…

Machine Learning · Computer Science 2016-05-31 Chongxuan Li , Jun Zhu , Bo Zhang

Compressed sensing (CS) leverages the sparsity prior to provide the foundation for fast magnetic resonance imaging (fastMRI). However, iterative solvers for ill-posed problems hinder their adaption to time-critical applications. Moreover,…

Image and Video Processing · Electrical Eng. & Systems 2021-03-16 Jingshuai Liu , Mehrdad Yaghoobi

In many clinical settings, the use of both Computed Tomography (CT) and Magnetic Resonance (MRI) is necessary to pursue a thorough understanding of the patient's anatomy and to plan a suitable therapeutical strategy; this is often the case…

Image and Video Processing · Electrical Eng. & Systems 2024-07-16 Leonardo Crespi , Samuele Camnasio , Damiano Dei , Nicola Lambri , Pietro Mancosu , Marta Scorsetti , Daniele Loiacono

Magnetic resonance imaging (MRI) inpainting supports numerous clinical and research applications. We introduce the first generative model that conditions on voxel-level, continuous tumor concentrations to synthesize high-fidelity brain…

Image and Video Processing · Electrical Eng. & Systems 2025-12-09 Valentin Biller , Lucas Zimmer , Ayhan Can Erdur , Sandeep Nagar , Daniel Rückert , Niklas Bubeck , Jonas Weidner

Segmentation and quantification of white matter hyperintensities (WMHs) are of great importance in studying and understanding various neurological and geriatric disorders. Although automatic methods have been proposed for WMH segmentation…

Computer Vision and Pattern Recognition · Computer Science 2018-03-20 Dakai Jin , Ziyue Xu , Adam P. Harrison , Daniel J. Mollura

While synthetic data hold great promise for privacy protection, their statistical analysis poses significant challenges that necessitate innovative solutions. The use of deep generative models (DGMs) for synthetic data generation is known…

Reconstructing digital brain phantoms in the form of voxel-based, multi-channeled tissue probability maps for individual subjects is essential for capturing brain anatomical variability, understanding neurological diseases, as well as for…

Computer Vision and Pattern Recognition · Computer Science 2024-07-02 Utkarsh Gupta , Emmanouil Nikolakakis , Moritz Zaiss , Razvan Marinescu

Training even moderately-sized generative models with differentially-private stochastic gradient descent (DP-SGD) is difficult: the required level of noise for reasonable levels of privacy is simply too large. We advocate instead building…

Machine Learning · Statistics 2023-07-21 Fredrik Harder , Milad Jalali Asadabadi , Danica J. Sutherland , Mijung Park

Accurate automatic classification of major tissue classes and the cerebrospinal fluid in pediatric MR scans of early childhood brains remains a challenge. A poor and highly variable grey matter and white matter contrast on T1-weighted MR…

Image and Video Processing · Electrical Eng. & Systems 2020-05-08 Nataliya Portman , Paule-J Toussaint , Alan C. Evans McConnell

Received waveforms contain rich information for both range information and environment semantics. However, its full potential is hard to exploit under multipath and non-line-of-sight conditions. This paper proposes a deep generative model…

Signal Processing · Electrical Eng. & Systems 2023-05-30 Yuxiao Li , Santiago Mazuelas , Yuan Shen

Diversity in data is critical for the successful training of deep learning models. Leveraged by a recurrent generative adversarial network, we propose the CT-SGAN model that generates large-scale 3D synthetic CT-scan volumes ($\geq…

Image and Video Processing · Electrical Eng. & Systems 2021-11-08 Ahmad Pesaranghader , Yiping Wang , Mohammad Havaei

Magnetic Resonance Imaging (MRI) is widely used in the pathological and functional studies of the brain, such as epilepsy, tumor diagnosis, etc. Automated accurate brain tissue segmentation like cerebro-spinal fluid (CSF), gray matter (GM),…

Computer Vision and Pattern Recognition · Computer Science 2018-08-07 Yao Sun , Yang Deng , Yue Xu , Shuo Zhang , Mingwang Zhu , Kehong Yuan

Deep learning requires large datasets for training (convolutional) networks with millions of parameters. In neuroimaging, there are few open datasets with more than 100 subjects, which makes it difficult to, for example, train a classifier…

Image and Video Processing · Electrical Eng. & Systems 2020-01-27 Anders Eklund
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