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Various structures in human physiology follow a treelike morphology, which often expresses complexity at very fine scales. Examples of such structures are intrathoracic airways, retinal blood vessels, and hepatic blood vessels. Large…

Image and Video Processing · Electrical Eng. & Systems 2022-09-23 Hao Li , Zeyu Tang , Yang Nan , Guang Yang

Brain decoding is a popular multivariate approach for hypothesis testing in neuroimaging. It is well known that the brain maps derived from weights of linear classifiers are hard to interpret because of high correlations between predictors,…

Machine Learning · Statistics 2016-03-30 Seyed Mostafa Kia

In this paper, we present a novel method for analysis and segmentation of laminar structure of the cortex based on tissue characteristics whose change across the gray matter underlies distinctive between cortical layers. We develop and…

Computer Vision and Pattern Recognition · Computer Science 2019-12-16 Andrija Štajduhar , Tomislav Lipić , Goran Sedmak , Sven Lončarić , Miloš Judaš

There is an increasing consensus among re- searchers that making a computer emotionally intelligent with the ability to decode human affective states would allow a more meaningful and natural way of human-computer interactions (HCIs). One…

Human-Computer Interaction · Computer Science 2016-06-02 Maria S. Perez-Rosero , Behnaz Rezaei , Murat Akcakaya , Sarah Ostadabbas

The human brain constitutes 2% of the total body mass, but consumes 20% of the oxygen. The rate of the brain's oxygen utilization can be determined from the knowledge of cerebral blood flow and oxygen extraction fraction (OEF). Therefore,…

Medical Physics · Physics 2022-02-04 Dengrong Jiang , Hanzhang Lu

This review paper delves into the present state of medical imaging, with a specific focus on the use of deep learning techniques for brain image synthesis. The need for medical image synthesis to improve diagnostic accuracy and decrease…

Image and Video Processing · Electrical Eng. & Systems 2023-09-20 Shubham Singh , Ammar Ranapurwala , Mrunal Bewoor , Sheetal Patil , Satyam Rai

The action potential is widely considered a purely electrical phenomenon. However, one also finds mechanical and thermal changes that can be observed experimentally. In particular, nerve membranes become thicker and axons contract. The…

Neurons and Cognition · Quantitative Biology 2025-09-29 T. Heimburg

In this study we present a kinematic approach to modeling needle insertion into soft tissues. The kinematic approach allows the presentation of the problem as Dirichlet-type (i.e. driven by enforced motion of boundaries) and therefore…

Medical Physics · Physics 2021-01-26 Adam Wittek , George Bourantas , Benjamin F. Zwick , Grand Joldes , Lionel Esteban , Karol Miller

Feature extraction is a method of capturing visual content of an image. The feature extraction is the process to represent raw image in its reduced form to facilitate decision making such as pattern classification. We have tried to address…

Computer Vision and Pattern Recognition · Computer Science 2012-08-13 V. P. Gladis Pushpa Rathi , S. Palani

The last decades saw dramatic progress in brain research. These advances were often buttressed by probing single variables to make circumscribed discoveries, typically through null hypothesis significance testing. New ways for generating…

Neurons and Cognition · Quantitative Biology 2019-03-26 Danilo Bzdok , John Ioannidis

The clinical application of patient-specific modelling of the heart can provide valuable insights in supplementing and advancing methods of diagnosis as well as helping to devise the best possible therapeutic approach for each individual…

Medical Physics · Physics 2023-08-03 Sebastian Skatulla , Carlo Sansour , Mary Familusi , Jagir Hussan , Ntobeko Ntusi

Molecular diffusion measurements are widely used to probe microstructure in materials and living organisms noninvasively. The precise relation of diffusion metrics to microstructure remains a major challenge: In complex samples, it is often…

Biological Physics · Physics 2014-04-15 Dmitry S. Novikov , Els Fieremans , Jens H. Jensen , Joseph A. Helpern

The introduction of computational techniques to analyze chemical data has given rise to the analytical study of biological systems, known as "bioinformatics". One facet of bioinformatics is using machine learning (ML) technology to detect…

Quantitative Methods · Quantitative Biology 2022-08-23 Tanish Jain , Praveen Kumar Pandian Shanmuganathan

Research in cognitive science has provided extensive evidence of human cognitive ability in performing physical reasoning of objects from noisy perceptual inputs. Such a cognitive ability is commonly known as intuitive physics. With…

Machine Learning · Computer Science 2022-04-29 Jiafei Duan , Arijit Dasgupta , Jason Fischer , Cheston Tan

Brain morphology is shaped by genetic and mechanical factors and is linked to biological development and diseases. Its fractal-like features, regional anisotropy, and complex curvature distributions hinder quantitative insights in medical…

Neurons and Cognition · Quantitative Biology 2025-09-09 Yingjie Zhao , Yicheng Song , Fan Xu , Zhiping Xu

Characterization of microstructures in live tissues is one of the keys to diagnosing early stages of pathology and understanding disease mechanisms. However, the extraction of reliable information on biomarkers based on microstructure…

Quantum Physics · Physics 2020-09-01 Analia Zwick , Dieter Suter , Gershon Kurizki , Gonzalo A. Alvarez

Fetal brain extraction is a necessary first step in most computational fetal brain MRI pipelines. However, it has been a very challenging task due to non-standard fetal head pose, fetal movements during examination, and vastly heterogeneous…

Image and Video Processing · Electrical Eng. & Systems 2024-10-28 Razieh Faghihpirayesh , Davood Karimi , Deniz Erdoğmuş , Ali Gholipour

Many morphogenetic processes involve mechanical rearrangement of epithelial tissues that is driven by precisely regulated cytoskeletal forces and cell adhesion. The mechanical state of the cell and intercellular adhesion are not only the…

Cell Behavior · Quantitative Biology 2015-06-03 Kevin K. Chiou , Lars Hufnagel , Boris I. Shraiman

To establish the tissue regions necessary to accurately represent the mechanics of the optic nerve head (ONH), imaging data of the ONH from 2 healthy subjects were used to create in vivo subject-specific eye mechanical models considering…

Medical Physics · Physics 2025-05-01 Soumaya Ouhsousou , Lucy Q. Shen , Chhavi Saini , Amin Pourasghar , Mengyu Wang , John C. Brigham

Dynamic functional connectivity is an effective measure for the brain's responses to continuous stimuli. We propose an inferential method to detect the dynamic changes of brain networks based on time-varying graphical models. Whereas most…

Applications · Statistics 2020-06-23 Dingjue Ji , Junwei Lu , Yiliang Zhang , Hongyu Zhao , Siyuan Gao