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Related papers: Weakly Semi-supervised Whole Slide Image Classific…

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This paper introduces the novel concept of few-shot weakly supervised learning for pathology Whole Slide Image (WSI) classification, denoted as FSWC. A solution is proposed based on prompt learning and the utilization of a large language…

Computer Vision and Pattern Recognition · Computer Science 2024-01-30 Linhao Qu , Xiaoyuan Luo , Kexue Fu , Manning Wang , Zhijian Song

We address the challenging problem of whole slide image (WSI) classification. WSIs have very high resolutions and usually lack localized annotations. WSI classification can be cast as a multiple instance learning (MIL) problem when only…

Computer Vision and Pattern Recognition · Computer Science 2021-04-05 Bin Li , Yin Li , Kevin W. Eliceiri

Digital histopathology whole slide images (WSIs) provide gigapixel-scale high-resolution images that are highly useful for disease diagnosis. However, digital histopathology image analysis faces significant challenges due to the limited…

Computer Vision and Pattern Recognition · Computer Science 2026-02-13 Bodong Zhang , Xiwen Li , Hamid Manoochehri , Xiaoya Tang , Deepika Sirohi , Beatrice S. Knudsen , Tolga Tasdizen

Multiple Instance Learning (MIL) has emerged as the best solution for Whole Slide Image (WSI) classification. It consists of dividing each slide into patches, which are treated as a bag of instances labeled with a global label. MIL includes…

Computer Vision and Pattern Recognition · Computer Science 2025-05-05 Ali Mammadov , Loic Le Folgoc , Julien Adam , Anne Buronfosse , Gilles Hayem , Guillaume Hocquet , Pietro Gori

Whole slide image (WSI) classification is a fundamental task for the diagnosis and treatment of diseases; but, curation of accurate labels is time-consuming and limits the application of fully-supervised methods. To address this, multiple…

Computer Vision and Pattern Recognition · Computer Science 2022-07-25 Philip Chikontwe , Soo Jeong Nam , Heounjeong Go , Meejeong Kim , Hyun Jung Sung , Sang Hyun Park

Computer-aided pathology diagnosis based on the classification of Whole Slide Image (WSI) plays an important role in clinical practice, and it is often formulated as a weakly-supervised Multiple Instance Learning (MIL) problem. Existing…

Computer Vision and Pattern Recognition · Computer Science 2022-10-11 Linhao Qu , Xiaoyuan Luo , Manning Wang , Zhijian Song

Recent advancements in computational pathology and artificial intelligence have significantly improved whole slide image (WSI) classification. However, the gigapixel resolution of WSIs and the scarcity of manual annotations present…

Computer Vision and Pattern Recognition · Computer Science 2024-08-26 Mingxi Ouyang , Yuqiu Fu , Renao Yan , ShanShan Shi , Xitong Ling , Lianghui Zhu , Yonghong He , Tian Guan

Whole slide image (WSI) refers to a type of high-resolution scanned tissue image, which is extensively employed in computer-assisted diagnosis (CAD). The extremely high resolution and limited availability of region-level annotations make…

Computer Vision and Pattern Recognition · Computer Science 2023-09-06 Ruijie Zhang , Qiaozhe Zhang , Yingzhuang Liu , Hao Xin , Yan Liu , Xinggang Wang

Weakly supervised whole slide image classification is usually formulated as a multiple instance learning (MIL) problem, where each slide is treated as a bag, and the patches cut out of it are treated as instances. Existing methods either…

Computer Vision and Pattern Recognition · Computer Science 2024-05-14 Linhao Qu , Yingfan Ma , Xiaoyuan Luo , Manning Wang , Zhijian Song

Whole Slide Image (WSI) classification remains a challenge due to their extremely high resolution and the absence of fine-grained labels. Presently, WSI classification is usually regarded as a Multiple Instance Learning (MIL) problem when…

Computer Vision and Pattern Recognition · Computer Science 2023-08-24 Hongyi Wang , Luyang Luo , Fang Wang , Ruofeng Tong , Yen-Wei Chen , Hongjie Hu , Lanfen Lin , Hao Chen

Whole-slide image (WSI) classification is a challenging task because 1) patches from WSI lack annotation, and 2) WSI possesses unnecessary variability, e.g., stain protocol. Recently, Multiple-Instance Learning (MIL) has made significant…

Computer Vision and Pattern Recognition · Computer Science 2025-08-12 Joohyung Lee , Heejeong Nam , Kwanhyung Lee , Sangchul Hahn

Whole slide images (WSIs) are gigapixel-scale digital images of H\&E-stained tissue samples widely used in pathology. The substantial size and complexity of WSIs pose unique analytical challenges. Multiple Instance Learning (MIL) has…

Computer Vision and Pattern Recognition · Computer Science 2024-08-20 Jun Wang , Yu Mao , Nan Guan , Chun Jason Xue

Whole Slide Image (WSI) analysis is a powerful method to facilitate the diagnosis of cancer in tissue samples. Automating this diagnosis poses various issues, most notably caused by the immense image resolution and limited annotations. WSIs…

Computer Vision and Pattern Recognition · Computer Science 2023-04-19 Ahmet Gokberk Gul , Oezdemir Cetin , Christoph Reich , Tim Prangemeier , Nadine Flinner , Heinz Koeppl

Multiple instance learning (MIL) problem is currently solved from either bag-classification or instance-classification perspective, both of which ignore important information contained in some instances and result in limited performance.…

Computer Vision and Pattern Recognition · Computer Science 2024-08-12 Yingfan Ma , Xiaoyuan Luo , Mingzhi Yuan , Xinrong Chen , Manning Wang

As advanced image manipulation techniques emerge, detecting the manipulation becomes increasingly important. Despite the success of recent learning-based approaches for image manipulation detection, they typically require expensive…

Computer Vision and Pattern Recognition · Computer Science 2023-09-06 Yuanhao Zhai , Tianyu Luan , David Doermann , Junsong Yuan

Classification of gigapixel Whole Slide Images (WSIs) is an important prediction task in the emerging area of computational pathology. There has been a surge of research in deep learning models for WSI classification with clinical…

Computer Vision and Pattern Recognition · Computer Science 2023-05-04 Sajid Javed , Arif Mahmood , Talha Qaiser , Naoufel Werghi , Nasir Rajpoot

While Multiple Instance Learning (MIL) has shown promising results in digital Pathology Whole Slide Image (WSI) classification, such a paradigm still faces performance and generalization problems due to challenges in high computational…

Computer Vision and Pattern Recognition · Computer Science 2023-03-16 Honglin Li , Chenglu Zhu , Yunlong Zhang , Yuxuan Sun , Zhongyi Shui , Wenwei Kuang , Sunyi Zheng , Lin Yang

Whole slide image (WSI) classification requires repetitive zoom-in and out for pathologists, as only small portions of the slide may be relevant to detecting cancer. Due to the lack of patch-level labels, multiple instance learning (MIL) is…

Computer Vision and Pattern Recognition · Computer Science 2023-11-30 Seongho Keum , Sanghyun Kim , Soojeong Lee , Juho Lee

In recent years, the availability of digitized Whole Slide Images (WSIs) has enabled the use of deep learning-based computer vision techniques for automated disease diagnosis. However, WSIs present unique computational and algorithmic…

Image and Video Processing · Electrical Eng. & Systems 2021-06-15 Yash Sharma , Aman Shrivastava , Lubaina Ehsan , Christopher A. Moskaluk , Sana Syed , Donald E. Brown

In computational pathology, multiple instance learning (MIL) is widely used to circumvent the computational impasse in giga-pixel whole slide image (WSI) analysis. It usually consists of two stages: patch-level feature extraction and…

Image and Video Processing · Electrical Eng. & Systems 2023-09-21 Beidi Zhao , Wenlong Deng , Zi Han , Li , Chen Zhou , Zuhua Gao , Gang Wang , Xiaoxiao Li
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