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Blood vessels (BVs) play a critical role in the Tumor Micro-Environment (TME), potentially influencing cancer progression and treatment response. However, manually quantifying BVs in Hematoxylin and Eosin (H&E) stained images is challenging…

Image and Video Processing · Electrical Eng. & Systems 2025-01-27 Jiaqi Lv , Stefan S Antonowicz , Shan E Ahmed Raza

Due to the cross-domain distribution shift aroused from diverse medical imaging systems, many deep learning segmentation methods fail to perform well on unseen data, which limits their real-world applicability. Recent works have shown the…

Computer Vision and Pattern Recognition · Computer Science 2023-03-06 Shangqi Gao , Hangqi Zhou , Yibo Gao , Xiahai Zhuang

Accurate segmentation of carotid artery structures in histopathological images is vital for cardiovascular disease research. This study systematically evaluates ten deep learning segmentation models including classical architectures, modern…

Computer Vision and Pattern Recognition · Computer Science 2026-04-07 Phongsakon Mark Konrad , Andrei-Alexandru Popa , Yaser Sabzehmeidani , Liang Zhong , Madhulika Tripathy , Andrei Constantinescu , Elisa A. Liehn , Serkan Ayvaz

Vessels are complex structures in the body that have been studied extensively in multiple representations. While voxelization is the most common of them, meshes and parametric models are critical in various applications due to their…

We propose a novel deep-learning-based system for vessel segmentation. Existing methods using CNNs have mostly relied on local appearances learned on the regular image grid, without considering the graphical structure of vessel shape. To…

Computer Vision and Pattern Recognition · Computer Science 2021-05-07 Seung Yeon Shin , Soochahn Lee , Il Dong Yun , Kyoung Mu Lee

Deep learning has been shown to produce state of the art results in many tasks in biomedical imaging, especially in segmentation. Moreover, segmentation of the cerebrovascular structure from magnetic resonance angiography is a challenging…

Computer Vision and Pattern Recognition · Computer Science 2018-12-06 Pedro Sanches , Cyril Meyer , Vincent Vigon , Benoît Naegel

Carotid artery vessel wall thickness measurement is an essential step in the monitoring of patients with atherosclerosis. This requires accurate segmentation of the vessel wall, i.e., the region between an artery's lumen and outer wall, in…

Image and Video Processing · Electrical Eng. & Systems 2021-12-03 Dieuwertje Alblas , Christoph Brune , Jelmer M. Wolterink

Incorporating human domain knowledge for breast tumor diagnosis is challenging, since shape, boundary, curvature, intensity, or other common medical priors vary significantly across patients and cannot be employed. This work proposes a new…

Image and Video Processing · Electrical Eng. & Systems 2020-09-03 Aleksandar Vakanski , Min Xian , Phoebe Freer

The remarkable success of deep learning has prompted interest in its application to medical imaging diagnosis. Even though state-of-the-art deep learning models have achieved human-level accuracy on the classification of different types of…

Image and Video Processing · Electrical Eng. & Systems 2023-09-20 Cristiano Patrício , João C. Neves , Luís F. Teixeira

Deep learning-based medical image analysis faces a significant barrier due to the lack of interpretability. Conventional explainable AI (XAI) techniques, such as Grad-CAM and SHAP, often highlight regions outside clinical interests. To…

Image and Video Processing · Electrical Eng. & Systems 2025-02-17 Yuhao Zhang , Mingcheng Zhu , Zhiyao Luo

In clinical practice, regions of interest in medical imaging often need to be identified through a process of precise image segmentation. The quality of this image segmentation step critically affects the subsequent clinical assessment of…

Image and Video Processing · Electrical Eng. & Systems 2021-03-23 João B. S. Carvalho , João A. Santinha , Đorđe Miladinović , Joachim M. Buhmann

Chronic wounds affect a large population, particularly the elderly and diabetic patients, who often exhibit limited mobility and co-existing health conditions. Automated wound monitoring via mobile image capture can reduce in-person…

Computer Vision and Pattern Recognition · Computer Science 2025-06-26 Vanessa Borst , Timo Dittus , Tassilo Dege , Astrid Schmieder , Samuel Kounev

Medical image segmentation has advanced rapidly over the past two decades, largely driven by deep learning, which has enabled accurate and efficient delineation of cells, tissues, organs, and pathologies across diverse imaging modalities.…

Image and Video Processing · Electrical Eng. & Systems 2025-08-29 Guoping Xu , Jayaram K. Udupa , Jax Luo , Songlin Zhao , Yajun Yu , Scott B. Raymond , Hao Peng , Lipeng Ning , Yogesh Rathi , Wei Liu , You Zhang

Deep learning techniques for 3D brain vessel image segmentation have not been as successful as in the segmentation of other organs and tissues. This can be explained by two factors. First, deep learning techniques tend to show poor…

Computer Vision and Pattern Recognition · Computer Science 2021-11-04 Vien Ngoc Dang , Francesco Galati , Rosa Cortese , Giuseppe Di Giacomo , Viola Marconetto , Prateek Mathur , Karim Lekadir , Marco Lorenzi , Ferran Prados , Maria A. Zuluaga

Deep learning-based computer-aided diagnosis is gradually deployed to review and analyze medical images. However, this paradigm is restricted in real-world clinical applications due to the poor robustness and generalization. The issue is…

Computer Vision and Pattern Recognition · Computer Science 2022-03-22 Yurong Chen

Accurate wound classification and boundary segmentation are essential for guiding clinical decisions in both chronic and acute wound management. However, most existing AI models are limited, focusing on a narrow set of wound types or…

Computer Vision and Pattern Recognition · Computer Science 2026-03-31 Mehedi Hasan Tusar , Fateme Fayyazbakhsh , Igor Melnychuk , Ming C. Leu

Medical image segmentation is crucial for accurate clinical diagnoses, yet it faces challenges such as low contrast between lesions and normal tissues, unclear boundaries, and high variability across patients. Deep learning has improved…

Image and Video Processing · Electrical Eng. & Systems 2024-12-09 Houze Liu , Tong Zhou , Yanlin Xiang , Aoran Shen , Jiacheng Hu , Junliang Du

Medical image segmentation (MIS) is a fundamental component of computer-assisted diagnosis and clinical decision support systems. Over the past decade, numerous architectures specifically tailored to medical imaging have emerged to address…

Computer Vision and Pattern Recognition · Computer Science 2026-03-16 Vanessa Borst , Samuel Kounev

Many studies regarding the vasculature of biological tissues involve the segmentation of the blood vessels in a sample followed by the creation of a graph structure to model the vasculature. The graph is then used to extract relevant…

Computer Vision and Pattern Recognition · Computer Science 2024-06-21 João Pedro Parella , Matheus Viana da Silva , Cesar Henrique Comin

Computed tomography image segmentation of complex abdominal aortic aneurysms (AAA) often fails because the models assign internal focus to irrelevant structures or do not focus on thin, low-contrast targets. Where the model looks is the…

Computer Vision and Pattern Recognition · Computer Science 2026-03-27 Abu Noman Md Sakib , Merjulah Roby , Zijie Zhang , Satish Muluk , Mark K. Eskandari , Ender A. Finol