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White blood cells (WBC) are important parts of our immune system, and they protect our body against infections by eliminating viruses, bacteria, parasites and fungi. The number of WBC types and the total number of WBCs provide important…

Computer Vision and Pattern Recognition · Computer Science 2026-03-05 Sibasish Dhibar

Automated white blood cell (WBC) classification is essential for scalable leukaemia screening. However, real-world deployment is challenged by domain shifts caused by staining protocols, scanner characteristics, and inter-laboratory…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Ruyi Dai , Tingkwong Ng , Hao Chen

White blood cell (WBC) classification is fundamental for hematology applications such as infection assessment, leukemia screening, and treatment monitoring. However, real-world WBC datasets present substantial appearance variations caused…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Luu Le , Hoang-Loc Cao , Ha-Hieu Pham , Thanh-Huy Nguyen , Ulas Bagci

Automated white blood cell (WBC) classification is essential for leukemia screening but remains challenged by extreme class imbalance, long-tail distributions, and domain shift, leading deep models to overfit dominant classes and fail on…

Computer Vision and Pattern Recognition · Computer Science 2026-03-31 Duc T. Nguyen , Hoang-Long Nguyen , Huy-Hieu Pham

Diagnosis of hematological malignancies depends on accurate identification of white blood cells in peripheral blood smears. Deep learning techniques are emerging as a viable solution to scale and optimize this process by automatic cell…

Computer Vision and Pattern Recognition · Computer Science 2024-08-01 Michael Deutges , Ario Sadafi , Nassir Navab , Carsten Marr

Machine learning (ML) and deep learning (DL) models have been employed to significantly improve analyses of medical imagery, with these approaches used to enhance the accuracy of prediction and classification. Model predictions and…

Image and Video Processing · Electrical Eng. & Systems 2023-08-22 Rabia Asghar , Sanjay Kumar , Paul Hynds , Arslan Shaukat

Cell detection in pathological images presents unique challenges due to densely packed objects, subtle inter-class differences, and severe background clutter. In this paper, we propose CellMamba, a lightweight and accurate one-stage…

Computer Vision and Pattern Recognition · Computer Science 2025-12-29 Ruochen Liu , Yi Tian , Jiahao Wang , Hongbin Liu , Xianxu Hou , Jingxin Liu

The classification of white blood cells (WBCs) from peripheral blood smears is critical for the diagnosis of leukemia. However, automated approaches still struggle due to challenges including class imbalance, domain shift, and morphological…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Antony Gitau , Martin Paulson , Bjørn-Jostein Singstad , Karl Thomas Hjelmervik , Ola Marius Lysaker , Veralia Gabriela Sanchez

Nuclei segmentation and classification provide an essential basis for tumor immune microenvironment analysis. The previous nuclei segmentation and classification models require splitting large images into smaller patches for training,…

Computer Vision and Pattern Recognition · Computer Science 2025-03-17 Ye Zhang , Zijie Fang , Yifeng Wang , Lingbo Zhang , Xianchao Guan , Yongbing Zhang

Decision Transformer, a promising approach that applies Transformer architectures to reinforcement learning, relies on causal self-attention to model sequences of states, actions, and rewards. While this method has shown competitive…

Machine Learning · Computer Science 2024-04-01 Toshihiro Ota

Automating white blood cell classification for diagnosis of leukaemia is a promising alternative to time-consuming and resource-intensive examination of cells by expert pathologists. However, designing robust algorithms for classification…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Siddharth Srivastava , Adam Smith , Scott Brooks , Jack Bacon , Till Bretschneider

Mamba, a special case of the State Space Model, is gaining popularity as an alternative to template-based deep learning approaches in medical image analysis. While transformers are powerful architectures, they have drawbacks, including…

Accurate classification of white blood cells in peripheral blood is essential for diagnosing hematological diseases. Due to constantly evolving clinical settings, data sources, and disease classifications, it is necessary to update machine…

Computer Vision and Pattern Recognition · Computer Science 2023-08-25 Ario Sadafi , Raheleh Salehi , Armin Gruber , Sayedali Shetab Boushehri , Pascal Giehr , Nassir Navab , Carsten Marr

Recently, a lot of automated white blood cells (WBC) or leukocyte classification techniques have been developed. However, all of these methods only utilize a single modality microscopic image i.e. either blood smear or fluorescence based,…

Image and Video Processing · Electrical Eng. & Systems 2022-08-18 Litao Yang , Deval Mehta , Dwarikanath Mahapatra , Zongyuan Ge

Recognizing the types of white blood cells (WBCs) in microscopic images of human blood smears is a fundamental task in the fields of pathology and hematology. Although previous studies have made significant contributions to the development…

Image and Video Processing · Electrical Eng. & Systems 2023-05-22 Satoshi Tsutsui , Zhengyang Su , Bihan Wen

White blood cell (WBC) classification plays a vital role in hematology for diagnosing various medical conditions. However, it faces significant challenges due to domain shifts caused by variations in sample sources (e.g., blood or bone…

Human immune system contains white blood cells (WBC) that are good indicator of many diseases like bacterial infections, AIDS, cancer, spleen, etc. White blood cells have been sub classified into four types: monocytes, lymphocytes,…

Image and Video Processing · Electrical Eng. & Systems 2024-10-15 Rabia Asghar , Arslan Shaukat , Usman Akram , Rimsha Tariq

U-shaped architectures have long dominated the field of medical image segmentation, while Transformers are widely employed for modeling long-range dependencies. The former typically handles scale variations implicitly by aggregating…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Yanhua Zhang , Ke Zhang , Jingyu Wang , Gabriella Balestra , Samanta Rosati , Yulin Wu , Wuwei Wang , Valentina Giannini

Mamba-based models, VMamba and Vim, are a recent family of vision encoders that offer promising performance improvements in many computer vision tasks. This paper compares Mamba-based models with traditional Convolutional Neural Networks…

Computer Vision and Pattern Recognition · Computer Science 2024-09-18 Ali Nasiri-Sarvi , Mahdi S. Hosseini , Hassan Rivaz

Accurate medical image segmentation demands the integration of multi-scale information, spanning from local features to global dependencies. However, it is challenging for existing methods to model long-range global information, where…

Image and Video Processing · Electrical Eng. & Systems 2024-03-07 Jiarun Liu , Hao Yang , Hong-Yu Zhou , Yan Xi , Lequan Yu , Yizhou Yu , Yong Liang , Guangming Shi , Shaoting Zhang , Hairong Zheng , Shanshan Wang
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