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Medical image segmentation is crucial for clinical diagnosis, yet existing models are limited by their reliance on explicit human instructions and lack the active reasoning capabilities to understand complex clinical questions. While recent…

Computer Vision and Pattern Recognition · Computer Science 2025-06-13 Yu Huang , Zelin Peng , Yichen Zhao , Piao Yang , Xiaokang Yang , Wei Shen

Despite recent progress in text-prompt-based medical image segmentation, these methods are limited to single-round dialogues and fail to support multi-round reasoning, which is important for medical education scenarios. In this work, we…

Computer Vision and Pattern Recognition · Computer Science 2026-03-12 Qinyue Tong , Ziqian Lu , Jun Liu , Rui Zuo , Zheming Lu , Yueming Jin

Despite significant progress in pixel-level medical image analysis, existing medical image segmentation models rarely explore medical segmentation and diagnosis tasks jointly. However, it is crucial for patients that models can provide…

Computer Vision and Pattern Recognition · Computer Science 2025-11-11 Lingran Song , Yucheng Zhou , Jianbing Shen

Prompt-based medical image segmentation has rapidly emerged, yet existing methods rely on explicit prompts like bounding boxes and struggle to reason about the spatial relationships essential for clinical diagnosis. While general-domain…

Computer Vision and Pattern Recognition · Computer Science 2026-04-01 Quoc-Huy Trinh , Minh-Van Nguyen , Jun Zeng , Debesh Jha , Ulas Bagci

Medical image segmentation is vital for modern healthcare and is a key element of computer-aided diagnosis. While recent advancements in computer vision have explored unsupervised segmentation using pre-trained models, these methods have…

Computer Vision and Pattern Recognition · Computer Science 2025-08-07 Mosong Ma , Tania Stathaki , Michalis Lazarou

Understanding human instructions to identify the target objects is vital for perception systems. In recent years, the advancements of Large Language Models (LLMs) have introduced new possibilities for image segmentation. In this work, we…

Computer Vision and Pattern Recognition · Computer Science 2024-04-16 Junchi Wang , Lei Ke

Medical image segmentation is challenging due to overlapping anatomies with ambiguous boundaries and a severe imbalance between the foreground and background classes, which particularly affects the delineation of small lesions. Existing…

Computer Vision and Pattern Recognition · Computer Science 2025-06-24 Hao Shao , Qibin Hou

Medical image segmentation remains challenging due to limited annotations for training, ambiguous anatomical features, and domain shifts. While vision-language models such as CLIP offer strong cross-modal representations, their potential…

Computer Vision and Pattern Recognition · Computer Science 2026-02-25 Taha Koleilat , Hojat Asgariandehkordi , Omid Nejati Manzari , Berardino Barile , Yiming Xiao , Hassan Rivaz

Accurate medical image segmentation is fundamental to precision medicine, yet robust delineation remains challenging under heterogeneous appearances, ambiguous boundaries, and large anatomical variability. Similar intensity and texture…

Computer Vision and Pattern Recognition · Computer Science 2026-05-15 Zhiquan Chen , Haitao Wang , Guowei Zou , Hejun Wu

Due to the cross-domain distribution shift aroused from diverse medical imaging systems, many deep learning segmentation methods fail to perform well on unseen data, which limits their real-world applicability. Recent works have shown the…

Computer Vision and Pattern Recognition · Computer Science 2023-03-06 Shangqi Gao , Hangqi Zhou , Yibo Gao , Xiahai Zhuang

While deep learning models have become the predominant method for medical image segmentation, they are typically not capable of generalizing to unseen segmentation tasks involving new anatomies, image modalities, or labels. Given a new…

Computer Vision and Pattern Recognition · Computer Science 2023-04-14 Victor Ion Butoi , Jose Javier Gonzalez Ortiz , Tianyu Ma , Mert R. Sabuncu , John Guttag , Adrian V. Dalca

Most current medical vision language models struggle to jointly generate diagnostic text and pixel-level segmentation masks in response to complex visual questions. This represents a major limitation towards clinical application, as…

Computer Vision and Pattern Recognition · Computer Science 2025-10-22 Chengrun Li , Corentin Royer , Haozhe Luo , Bastian Wittmann , Xia Li , Ibrahim Hamamci , Sezgin Er , Anjany Sekuboyina , Bjoern Menze

Medical image segmentation is fundamental for biomedical discovery. Existing methods lack generalizability and demand extensive, time-consuming manual annotation for new clinical application. Here, we propose MedSAM-3, a text promptable…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Anglin Liu , Rundong Xue , Xu R. Cao , Yifan Shen , Yi Lu , Xiang Li , Qianqian Chen , Jintai Chen

Medical image segmentation has advanced rapidly over the past two decades, largely driven by deep learning, which has enabled accurate and efficient delineation of cells, tissues, organs, and pathologies across diverse imaging modalities.…

Image and Video Processing · Electrical Eng. & Systems 2025-08-29 Guoping Xu , Jayaram K. Udupa , Jax Luo , Songlin Zhao , Yajun Yu , Scott B. Raymond , Hao Peng , Lipeng Ning , Yogesh Rathi , Wei Liu , You Zhang

Medical image segmentation allows quantifying target structure size and shape, aiding in disease diagnosis, prognosis, surgery planning, and comprehension.Building upon recent advancements in foundation Vision-Language Models (VLMs) from…

Computer Vision and Pattern Recognition · Computer Science 2024-06-21 Kanchan Poudel , Manish Dhakal , Prasiddha Bhandari , Rabin Adhikari , Safal Thapaliya , Bishesh Khanal

The semantic image segmentation task consists of classifying each pixel of an image into an instance, where each instance corresponds to a class. This task is a part of the concept of scene understanding or better explaining the global…

Computer Vision and Pattern Recognition · Computer Science 2024-04-02 Saeid Asgari Taghanaki , Kumar Abhishek , Joseph Paul Cohen , Julien Cohen-Adad , Ghassan Hamarneh

Integrating high-level semantically correlated contents and low-level anatomical features is of central importance in medical image segmentation. Towards this end, recent deep learning-based medical segmentation methods have shown great…

Computer Vision and Pattern Recognition · Computer Science 2023-07-19 Chenyu You , Weicheng Dai , Yifei Min , Lawrence Staib , James S. Duncan

Medical image segmentation is more clinically valuable when it supports diagnosis rather than merely producing lesion masks. However, diagnostically relevant lesion cues are often subtle and localized, while existing models may be…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Fengyi Zhang , Xujie Zeng , Mohan Liu , Zengyi Wang , Yalong Jiang

Accurately grounding regions of interest (ROIs) is critical for diagnosis and treatment planning in medical imaging. While multimodal large language models (MLLMs) combine visual perception with natural language, current medical-grounding…

Computer Vision and Pattern Recognition · Computer Science 2026-02-19 Zhonghao Yan , Muxi Diao , Yuxuan Yang , Ruoyan Jing , Jiayuan Xu , Kaizhou Zhang , Lele Yang , Yanxi Liu , Kongming Liang , Zhanyu Ma

Although perception systems have made remarkable advancements in recent years, they still rely on explicit human instruction or pre-defined categories to identify the target objects before executing visual recognition tasks. Such systems…

Computer Vision and Pattern Recognition · Computer Science 2024-05-02 Xin Lai , Zhuotao Tian , Yukang Chen , Yanwei Li , Yuhui Yuan , Shu Liu , Jiaya Jia
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