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The analysis of adverse events (AEs) is a key component in the assessment of a drug's safety profile. Inappropriate analysis methods may result in misleading conclusions about a therapy's safety and consequently its benefit-risk ratio. The…

Handling contaminated data poses a critical challenge in anomaly detection, as traditional models assume training on purely normal data. Conventional methods mitigate contamination by relying on fixed contamination ratios, but discrepancies…

Machine Learning · Computer Science 2025-11-27 Jungi Lee , Jungkwon Kim , Chi Zhang , Kwangsun Yoo , Seok-Joo Byun

The emergence of visual autoregressive (AR) models has revolutionized image generation while presenting new challenges for synthetic image detection. Unlike previous GAN or diffusion-based methods, AR models generate images through discrete…

Computer Vision and Pattern Recognition · Computer Science 2025-10-08 Yanran Zhang , Bingyao Yu , Yu Zheng , Wenzhao Zheng , Yueqi Duan , Lei Chen , Jie Zhou , Jiwen Lu

Source number detection is a critical problem in array signal processing. Conventional model-driven methods e.g., Akaikes information criterion (AIC) and minimum description length (MDL), suffer from severe performance degradation when the…

Information Theory · Computer Science 2020-02-19 Yuwen Yang , Feifei Gao , Cheng Qian , Guisheng Liao

In this paper we propose a new methodology for solving a discrete time stochastic Markovian control problem under model uncertainty. By utilizing the Dirichlet process, we model the unknown distribution of the underlying stochastic process…

Optimization and Control · Mathematics 2022-03-29 Tao Chen , Jiyoun Myung

This study aimed to systematically identify and quantify risks for drug-induced rhabdomyolysis (DIR) using real-world data and to propose an evidence-based risk mitigation framework. We conducted a retrospective pharmacovigilance study…

Other Quantitative Biology · Quantitative Biology 2025-11-04 Enpu Liang

Adverse drug events (ADEs) are a serious health problem that can be life-threatening. While a lot of studies have been performed on detect correlation between a drug and an AE, limited studies have been conducted on personalized ADE risk…

Machine Learning · Computer Science 2021-04-20 Jinhe Shi , Xiangyu Gao , Chenyu Ha , Yage Wang , Guodong Gao , Yi Chen

Adversarial detection aims to determine whether a given sample is an adversarial one based on the discrepancy between natural and adversarial distributions. Unfortunately, estimating or comparing two data distributions is extremely…

Machine Learning · Computer Science 2023-05-26 Shuhai Zhang , Feng Liu , Jiahao Yang , Yifan Yang , Changsheng Li , Bo Han , Mingkui Tan

Adverse drug reaction (ADR) detection is an essential task in the medical field, as ADRs have a gravely detrimental impact on patients' health and the healthcare system. Due to a large number of people sharing information on social media…

Computation and Language · Computer Science 2023-08-21 Yunzhi Qiu , Xiaokun Zhang , Weiwei Wang , Tongxuan Zhang , Bo Xu , Hongfei Lin

In this paper, we study the design and analysis of optimal detection scheme for sensors that are deployed to monitor the change in the environment and are powered by the energy harvested from the environment. In this type of applications,…

Information Theory · Computer Science 2015-06-15 Jun Geng , Lifeng Lai

Bayesian Additive Regression Trees (BART) is a fully Bayesian approach to modeling with ensembles of trees. BART can uncover complex regression functions with high dimensional regressors in a fairly automatic way and provide Bayesian…

Machine Learning · Statistics 2018-07-11 Edward George , Prakash Laud , Brent Logan , Robert McCulloch , Rodney Sparapani

Detecting anomalies for multivariate time-series without manual supervision continues a challenging problem due to the increased scale of dimensions and complexity of today's IT monitoring systems. Recent progress of unsupervised…

Machine Learning · Computer Science 2021-10-19 Qinfeng Xiao , Shikuan Shao , Jing Wang

Anomaly detection tools and methods present a key capability in modern cyberphysical and failure prediction systems. Despite the fast-paced development in deep learning architectures for anomaly detection, model optimization for a given…

Machine Learning · Computer Science 2023-05-29 Marcin Pietron , Dominik Zurek , Kamil Faber , Roberto Corizzo

We consider a multi-object detection problem over a sensor network (SNET) with limited range sensors. This problem complements the widely considered decentralized detection problem where all sensors observe the same object. While the…

Information Theory · Computer Science 2016-11-17 Erhan B. Ermis , Venkatesh Saligrama

Predicting drug side-effects before they occur is a key task in keeping the number of drug-related hospitalizations low and to improve drug discovery processes. Automatic predictors of side-effects generally are not able to process the…

Machine Learning · Statistics 2022-12-01 Pietro Bongini , Elisa Messori , Niccolò Pancino , Monica Bianchini

Cost-effectiveness analyses (CEAs) are at the center of health economic decision making. While these analyses help policy analysts and economists determine coverage, inform policy, and guide resource allocation, they are statistically…

Methodology · Statistics 2020-09-10 Arman Oganisian , Nandita Mitra , Jason Roy

Distribution system state estimation (DSSE) is paramount for effective state monitoring and control. However, stochastic outputs of renewables and asynchronous streaming of multi-rate measurements in practical systems largely degrade the…

Systems and Control · Electrical Eng. & Systems 2023-10-23 Ying Zhang , Junbo Zhao , Di Shi , Sungjoo Chung

Local differential privacy (LDP) is a strong privacy standard that has been adopted by popular software systems. The main idea is that each individual perturbs their own data locally, and only submits the resulting noisy version to a data…

Cryptography and Security · Computer Science 2024-04-04 Fei Wei , Ergute Bao , Xiaokui Xiao , Yin Yang , Bolin Ding

Identifying anomalous patterns in real-world data is essential for understanding where, when, and how systems deviate from their expected dynamics. Yet methods that separately consider the anomalousness of each individual data point have…

Machine Learning · Statistics 2018-04-05 William Herlands , Edward McFowland , Andrew Gordon Wilson , Daniel B. Neill

Graphical model has been widely used to investigate the complex dependence structure of high-dimensional data, and it is common to assume that observed data follow a homogeneous graphical model. However, observations usually come from…

Methodology · Statistics 2016-01-01 Kevin Lee , Lingzhou Xue
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