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Objective: Applying large language models (LLMs) to the clinical domain is challenging due to the context-heavy nature of processing medical records. Retrieval-augmented generation (RAG) offers a solution by facilitating reasoning over…

Computation and Language · Computer Science 2025-08-21 Skatje Myers , Timothy A. Miller , Yanjun Gao , Matthew M. Churpek , Anoop Mayampurath , Dmitriy Dligach , Majid Afshar

Large knowledge bases (KBs) are useful for many AI tasks, but are difficult to integrate into modern gradient-based learning systems. Here we describe a framework for accessing soft symbolic database using only differentiable operators. For…

Machine Learning · Computer Science 2019-05-16 William W. Cohen , Matthew Siegler , Alex Hofer

Retrieval-Augmented Generation (RAG) enables large language models (LLMs) to access broader knowledge sources, yet factual inconsistencies persist due to noise in retrieved documents-even with advanced retrieval methods. We demonstrate that…

Computation and Language · Computer Science 2025-06-04 Yongjian Li , HaoCheng Chu , Yukun Yan , Zhenghao Liu , Shi Yu , Zheni Zeng , Ruobing Wang , Sen Song , Zhiyuan Liu , Maosong Sun

Electronic Health Records (EHRs) are pivotal in clinical practices, yet their retrieval remains a challenge mainly due to semantic gap issues. Recent advancements in dense retrieval offer promising solutions but existing models, both…

Information Retrieval · Computer Science 2025-07-25 Zhengyun Zhao , Huaiyuan Ying , Yue Zhong , Sheng Yu

Biological relation networks contain rich information for understanding the biological mechanisms behind the relationship of entities such as genes, proteins, diseases, and chemicals. The vast growth of biomedical literature poses…

Computation and Language · Computer Science 2025-01-27 Po-Ting Lai , Chih-Hsuan Wei , Shubo Tian , Robert Leaman , Zhiyong Lu

Large language models (LLMs) typically enhance their performance through either the retrieval of semantically similar information or the improvement of their reasoning capabilities. However, a significant challenge remains in effectively…

Artificial Intelligence · Computer Science 2026-01-05 Shuqi Liu , Bowei He , Chen Ma , Linqi Song

Biomedical relation extraction (RE) is the task of automatically identifying and characterizing relations between biomedical concepts from free text. RE is a central task in biomedical natural language processing (NLP) research and plays a…

Computation and Language · Computer Science 2023-06-21 Po-Ting Lai , Chih-Hsuan Wei , Ling Luo , Qingyu Chen , Zhiyong Lu

Two key obstacles in biomedical relation extraction (RE) are the scarcity of annotations and the prevalence of instances without explicitly pre-defined labels due to low annotation coverage. Existing approaches, which treat biomedical RE as…

Computation and Language · Computer Science 2023-10-20 Jiashu Xu , Mingyu Derek Ma , Muhao Chen

The Covid-19 pandemic has caused a spur in the medical research literature. With new research advances in understanding the virus, there is a need for robust text mining tools which can process, extract and present answers from the…

Information Retrieval · Computer Science 2021-08-04 Souvik Das , Sougata Saha , Rohini K. Srihari

Neural networks with deep architectures have demonstrated significant performance improvements in computer vision, speech recognition, and natural language processing. The challenges in information retrieval (IR), however, are different…

Information Retrieval · Computer Science 2021-03-23 Bhaskar Mitra

Neuroscience research publications encompass a vast wealth of knowledge. Accurately retrieving existing information and discovering new insights from this extensive literature is essential for advancing the field. However, when knowledge is…

Computation and Language · Computer Science 2025-10-28 Pralaypati Ta , Sriram Venkatesaperumal , Keerthi Ram , Mohanasankar Sivaprakasam

This work presents a Biomedical Literature Question Answering (Q&A) system based on a Retrieval-Augmented Generation (RAG) architecture, designed to improve access to accurate, evidence-based medical information. Addressing the shortcomings…

Computation and Language · Computer Science 2025-09-09 Mansi Garg , Lee-Chi Wang , Bhavesh Ghanchi , Sanjana Dumpala , Shreyash Kakde , Yen Chih Chen

Information Retrieval (IR) is the task of obtaining pieces of data (such as documents) that are relevant to a particular query or need from a large repository of information. IR is a valuable component of several downstream Natural Language…

Information Retrieval · Computer Science 2020-08-05 Samarth Rawal

Constructing large-scaled medical knowledge graphs can significantly boost healthcare applications for medical surveillance, bring much attention from recent research. An essential step in constructing large-scale MKG is extracting…

Computer Vision and Pattern Recognition · Computer Science 2021-10-27 Jialun Wu , Yang Liu , Zeyu Gao , Tieliang Gong , Chunbao Wang , Chen Li

An important component of human analysis of medical images and their context is the ability to relate newly seen things to related instances in our memory. In this paper we mimic this ability by using multi-modal retrieval augmentation and…

Computer Vision and Pattern Recognition · Computer Science 2023-02-23 Tom van Sonsbeek , Marcel Worring

Due to globalization, geographic boundaries no longer serve as effective shields for the spread of infectious diseases. In order to aid bio-surveillance analysts in disease tracking, recent research has been devoted to developing…

Information Retrieval · Computer Science 2019-02-19 Aaron Tuor , Fnu Anubhav , Lauren Charles

Academic Search is a search task aimed to manage and retrieve scientific documents like journal articles and conference papers. Personalization in this context meets individual researchers' needs by leveraging, through user profiles, the…

Information Retrieval · Computer Science 2025-07-21 Pranav Kasela , Gabriella Pasi , Raffaele Perego

Recent proprietary large language models (LLMs), such as GPT-4, have achieved a milestone in tackling diverse challenges in the biomedical domain, ranging from multiple-choice questions to long-form generations. To address challenges that…

Computation and Language · Computer Science 2024-06-19 Minbyul Jeong , Jiwoong Sohn , Mujeen Sung , Jaewoo Kang

Large language models (LLMs) have demonstrated significant potential in clinical decision support. Yet LLMs still suffer from hallucinations and lack fine-grained contextual medical knowledge, limiting their high-stake healthcare…

Computation and Language · Computer Science 2025-04-22 Pengcheng Jiang , Cao Xiao , Minhao Jiang , Parminder Bhatia , Taha Kass-Hout , Jimeng Sun , Jiawei Han

Extracting fine-grained experimental findings from literature can provide dramatic utility for scientific applications. Prior work has developed annotation schemas and datasets for limited aspects of this problem, failing to capture the…

Computation and Language · Computer Science 2024-04-26 Aakanksha Naik , Bailey Kuehl , Erin Bransom , Doug Downey , Tom Hope
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