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Large Language Models (LLMs) have become indispensable tools in science, technology, and society, enabling transformative advances across diverse fields. However, errors or outdated information within these models can undermine their…

Computation and Language · Computer Science 2025-12-19 Qizhou Chen , Chengyu Wang , Taolin Zhang , Xiaofeng He

Lifelong model editing (LME) aims to sequentially rectify outdated or inaccurate knowledge in deployed LLMs while minimizing side effects on unrelated inputs. However, existing approaches typically apply parameter perturbations to a static…

Computation and Language · Computer Science 2026-04-14 Yangfan Wang , Tianyang Sun , Chen Tang , Jie Liu , Wei Cai , Jingchi Jiang

Engineering LLMs to accelerate life sciences research requires a robust alignment with biomedical knowledge. We observe that biomedical text exhibits a fundamentally different uncertainty structure from general text: dense low-confidence…

Large language models (LLMs) have excelled across domains, also delivering notable performance on the medical evaluation benchmarks, such as MedQA. However, there still exists a significant gap between the reported performance and the…

Computation and Language · Computer Science 2024-06-06 Yuxuan Zhou , Xien Liu , Chen Ning , Ji Wu

Large Language Models (LLMs) contain large amounts of facts about the world. These facts can become outdated over time, which has led to the development of knowledge editing methods (KEs) that can change specific facts in LLMs with limited…

Computation and Language · Computer Science 2025-06-18 Paul Youssef , Zhixue Zhao , Daniel Braun , Jörg Schlötterer , Christin Seifert

Large language models (LLMs) encode vast world knowledge but struggle to stay up-to-date, often leading to errors and hallucinations. Knowledge editing offers an efficient alternative to retraining, enabling targeted modifications by…

Computation and Language · Computer Science 2025-06-03 Weitao Ma , Xiyuan Du , Xiaocheng Feng , Lei Huang , Yichong Huang , Huiyi Zhang , Xiaoliang Yang , Baohang Li , Xiachong Feng , Ting Liu , Bing Qin

Knowledge editing in Large Language Models (LLMs) aims to update the model's prediction for a specific query to a desired target while preserving its behavior on all other inputs. This process typically involves two stages: identifying the…

Machine Learning · Computer Science 2026-05-18 Shrestha Datta , Hongfu Liu , Anshuman Chhabra

Knowledge editing (KE) provides a scalable approach for updating factual knowledge in large language models without full retraining. While previous studies have demonstrated effectiveness in general domains and medical QA tasks, little…

Artificial Intelligence · Computer Science 2025-08-12 Shengtao Wen , Haodong Chen , Yadong Wang , Zhongying Pan , Xiang Chen , Yu Tian , Bo Qian , Dong Liang , Sheng-Jun Huang

Large Language Models (LLMs) are increasingly adopted for applications in healthcare, reaching the performance of domain experts on tasks such as question answering and document summarisation. Despite their success on these tasks, it is…

Computation and Language · Computer Science 2025-05-20 Aishik Nagar , Viktor Schlegel , Thanh-Tung Nguyen , Hao Li , Yuping Wu , Kuluhan Binici , Stefan Winkler

The swift advancement in Multimodal LLMs (MLLMs) also presents significant challenges for effective knowledge editing. Current methods, including intrinsic knowledge editing and external knowledge resorting, each possess strengths and…

Computer Vision and Pattern Recognition · Computer Science 2024-11-01 Kaihang Pan , Zhaoyu Fan , Juncheng Li , Qifan Yu , Hao Fei , Siliang Tang , Richang Hong , Hanwang Zhang , Qianru Sun

Knowledge editing is a technique for efficiently and accurately updating the knowledge of large language models (LLMs) to alleviate obsolescence and correct errors. However, most existing methods overfit to specific models, causing edited…

Artificial Intelligence · Computer Science 2025-03-05 Shuaike Li , Kai Zhang , Qi Liu , Enhong Chen

In recent years, Large Language Models (LLMs) have demonstrated an impressive ability to encode knowledge during pre-training on large text corpora. They can leverage this knowledge for downstream tasks like question answering (QA), even in…

Computation and Language · Computer Science 2024-06-11 Juraj Vladika , Phillip Schneider , Florian Matthes

Problem-solving has been a fundamental driver of human progress in numerous domains. With advancements in artificial intelligence, Large Language Models (LLMs) have emerged as powerful tools capable of tackling complex problems across…

Machine Learning · Computer Science 2025-05-07 Da Zheng , Lun Du , Junwei Su , Yuchen Tian , Yuqi Zhu , Jintian Zhang , Lanning Wei , Ningyu Zhang , Huajun Chen

The rapid advancement of large language models (LLMs) in biological-medical applications has highlighted a gap between their potential and the limited scale and often low quality of available open-source annotated textual datasets. In…

Computation and Language · Computer Science 2025-12-19 Xunxin Cai , Chengrui Wang , Qingqing Long , Yuanchun Zhou , Meng Xiao

Knowledge editing techniques have emerged as essential tools for updating the factual knowledge of large language models (LLMs) and multimodal models (LMMs), allowing them to correct outdated or inaccurate information without retraining…

Computation and Language · Computer Science 2025-03-04 Yuntao Du , Kailin Jiang , Zhi Gao , Chenrui Shi , Zilong Zheng , Siyuan Qi , Qing Li

Predicting user behavior is essential for intelligent assistant services, yet deep learning models often struggle to capture long-tailed behaviors. Large language models (LLMs), with their pretraining on vast corpora containing rich…

Computation and Language · Computer Science 2026-04-14 Fanjin Meng , Jingtao Ding , Jiahui Gong , Chen Yang , Hong Chen , Zuojian Wang , Haisheng Lu , Yong Li

The rapid advancement of large language models (LLMs) and multimodal learning has transformed digital content creation and manipulation. Traditional visual editing tools require significant expertise, limiting accessibility. Recent strides…

Computer Vision and Pattern Recognition · Computer Science 2024-11-22 Thanh Tam Nguyen , Zhao Ren , Trinh Pham , Thanh Trung Huynh , Phi Le Nguyen , Hongzhi Yin , Quoc Viet Hung Nguyen

Large Language Models (LLMs) have shown capabilities close to human performance in various analytical tasks, leading researchers to use them for time and labor-intensive analyses. However, their capability to handle highly specialized and…

Computation and Language · Computer Science 2024-10-08 Alexander S. Choi , Syeda Sabrina Akter , JP Singh , Antonios Anastasopoulos

Large language models (LLMs) are deployed on mobile devices to power killer applications such as intelligent assistants. LLMs pre-trained on general corpora often hallucinate when handling personalized or unseen queries, leading to…

Machine Learning · Computer Science 2025-06-18 Zhenyan Lu , Daliang Xu , Dongqi Cai , Zexi Li , Wei Liu , Fangming Liu , Shangguang Wang , Mengwei Xu

Recent breakthroughs in large language models (LLMs) offer unprecedented natural language understanding and generation capabilities. However, existing surveys on LLMs in biomedicine often focus on specific applications or model…