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Recent Multimodal Large Language Models (MLLMs) have demonstrated significant progress in perceiving and reasoning over multimodal inquiries, ushering in a new research era for foundation models. However, vision-language misalignment in…

Computer Vision and Pattern Recognition · Computer Science 2026-05-18 Wei-Yao Wang , Zhao Wang , Helen Suzuki , Yoshiyuki Kobayashi

Deep learning algorithms require extensive data to achieve robust performance. However, data availability is often restricted in the medical domain due to patient privacy concerns. Synthetic data presents a possible solution to these…

Genome-wide association studies (GWAS) are used to identify relationships between genetic variations and specific traits. When applied to high-dimensional medical imaging data, a key step is to extract lower-dimensional, yet informative…

Quantitative Methods · Quantitative Biology 2023-09-28 Yaochen Xie , Ziqian Xie , Sheikh Muhammad Saiful Islam , Degui Zhi , Shuiwang Ji

Despite significant advancements in general AI, its effectiveness in the medical domain is limited by the lack of specialized medical knowledge. To address this, we formulate GMAI-VL-5.5M, a multimodal medical dataset created by converting…

Computer Vision and Pattern Recognition · Computer Science 2025-03-28 Tianbin Li , Yanzhou Su , Wei Li , Bin Fu , Zhe Chen , Ziyan Huang , Guoan Wang , Chenglong Ma , Ying Chen , Ming Hu , Yanjun Li , Pengcheng Chen , Xiaowei Hu , Zhongying Deng , Yuanfeng Ji , Jin Ye , Yu Qiao , Junjun He

We present VoxelMorph, a fast learning-based framework for deformable, pairwise medical image registration. Traditional registration methods optimize an objective function for each pair of images, which can be time-consuming for large…

Computer Vision and Pattern Recognition · Computer Science 2019-09-04 Guha Balakrishnan , Amy Zhao , Mert R. Sabuncu , John Guttag , Adrian V. Dalca

Medical imaging analysis plays a critical role in the diagnosis and treatment of various medical conditions. This paper focuses on chest X-ray images and their corresponding radiological reports. It presents a new model that learns a joint…

Computer Vision and Pattern Recognition · Computer Science 2023-03-22 Gefen Dawidowicz , Elad Hirsch , Ayellet Tal

Deformable image registration is a fundamental requirement for medical image analysis. Recently, transformers have been widely used in deep learning-based registration methods for their ability to capture long-range dependency via…

Image and Video Processing · Electrical Eng. & Systems 2024-12-25 Mingyuan Meng , Michael Fulham , Lei Bi , Jinman Kim

This study aimed to enhance disease classification accuracy from retinal fundus images by integrating fine-grained image features and global textual context using a novel multimodal deep learning architecture. Existing multimodal large…

Computer Vision and Pattern Recognition · Computer Science 2025-09-29 Jason Jordan , Mohammadreza Akbari Lor , Peter Koulen , Mei-Ling Shyu , Shu-Ching Chen

Medical Multi-modal Large Language Models (MLLMs) have shown promising clinical performance. However, their sensitivity to real-world input perturbations, such as imaging artifacts and textual errors, critically undermines their clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-12-29 Dunyuan XU , Xikai Yang , Yaoqian Li , Juzheng Miao , Jinpeng Li , Pheng-Ann Heng

Multi-task learning is a type of transfer learning that trains multiple tasks simultaneously and leverages the shared information between related tasks to improve the generalization performance. However, missing features in the input matrix…

Machine Learning · Statistics 2018-07-09 Xin J. Hunt , Saba Emrani , Ilknur Kaynar Kabul , Jorge Silva

We present DualFocus, a novel framework for integrating macro and micro perspectives within multi-modal large language models (MLLMs) to enhance vision-language task performance. Current MLLMs typically singularly focus on inputs at a…

Computer Vision and Pattern Recognition · Computer Science 2024-02-23 Yuhang Cao , Pan Zhang , Xiaoyi Dong , Dahua Lin , Jiaqi Wang

Current multimodal and multitask foundation models like 4M or UnifiedIO show promising results, but in practice their out-of-the-box abilities to accept diverse inputs and perform diverse tasks are limited by the (usually rather small)…

Computer Vision and Pattern Recognition · Computer Science 2024-06-17 Roman Bachmann , Oğuzhan Fatih Kar , David Mizrahi , Ali Garjani , Mingfei Gao , David Griffiths , Jiaming Hu , Afshin Dehghan , Amir Zamir

Dense pixel-specific representation learning at scale has been bottlenecked due to the unavailability of large-scale multi-view datasets. Current methods for building effective pretraining datasets heavily rely on annotated 3D meshes, point…

Computer Vision and Pattern Recognition · Computer Science 2024-05-17 Kalyani Marathe , Mahtab Bigverdi , Nishat Khan , Tuhin Kundu , Patrick Howe , Sharan Ranjit S , Anand Bhattad , Aniruddha Kembhavi , Linda G. Shapiro , Ranjay Krishna

Multitask learning assumes that models capable of learning from multiple tasks can achieve better quality and efficiency via knowledge transfer, a key feature of human learning. Though, state of the art ML models rely on high customization…

Machine Learning · Computer Science 2022-11-17 Andrea Gesmundo , Jeff Dean

Tabular Foundation Models have recently established the state of the art in supervised tabular learning, by leveraging pretraining to learn generalizable representations of numerical and categorical structured data. However, they lack…

Medical visual question answering (VQA) is a challenging multimodal task, where Vision-Language Pre-training (VLP) models can effectively improve the generalization performance. However, most methods in the medical field treat VQA as an…

Computer Vision and Pattern Recognition · Computer Science 2024-06-21 Jiawei Chen , Dingkang Yang , Yue Jiang , Yuxuan Lei , Lihua Zhang

Clinical decision support systems require models that are not only highly accurate but also equitable and sensitive to the implications of missed diagnoses. In this study, we introduce a knowledge-guided in-context learning (ICL) framework…

Machine Learning · Computer Science 2025-07-28 Fatemeh Nazary , Yashar Deldjoo , Tommaso Di Noia , Eugenio di Sciascio

Machine learning and deep learning methods have become essential for computer-assisted prediction in medicine, with a growing number of applications also in the field of mammography. Typically these algorithms are trained for a specific…

Image and Video Processing · Electrical Eng. & Systems 2021-12-03 Maria Wimmer , Gert Sluiter , David Major , Dimitrios Lenis , Astrid Berg , Theresa Neubauer , Katja Bühler

Vision language models (VLMs) achieve strong performance on general image understanding but struggle to think with medical images, especially when performing multi-step reasoning through iterative visual interaction. Medical VLMs often rely…

Computer Vision and Pattern Recognition · Computer Science 2026-01-13 Meng Lu , Yuxing Lu , Yuchen Zhuang , Megan Mullins , Yang Xie , Guanghua Xiao , Charles Fleming , Wenqi Shi , Xuan Wang
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