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Biomedical data is inherently multimodal, consisting of electronic health records, medical imaging, digital pathology, genome sequencing, wearable sensors, and more. The application of artificial intelligence tools to these multifaceted…

Machine Learning · Computer Science 2024-08-26 Shentong Mo , Paul Pu Liang

Deep learning methods have revolutionized speech recognition, image recognition, and natural language processing since 2010. Each of these tasks involves a single modality in their input signals. However, many applications in the artificial…

Artificial Intelligence · Computer Science 2020-07-15 Chao Zhang , Zichao Yang , Xiaodong He , Li Deng

Multimodal learning leverages complementary information derived from different modalities, thereby enhancing performance in medical image segmentation. However, prevailing multimodal learning methods heavily rely on extensive well-annotated…

Computer Vision and Pattern Recognition · Computer Science 2024-09-05 Xiaogen Zhou , Yiyou Sun , Min Deng , Winnie Chiu Wing Chu , Qi Dou

Dense pixel-specific representation learning at scale has been bottlenecked due to the unavailability of large-scale multi-view datasets. Current methods for building effective pretraining datasets heavily rely on annotated 3D meshes, point…

Computer Vision and Pattern Recognition · Computer Science 2024-05-17 Kalyani Marathe , Mahtab Bigverdi , Nishat Khan , Tuhin Kundu , Patrick Howe , Sharan Ranjit S , Anand Bhattad , Aniruddha Kembhavi , Linda G. Shapiro , Ranjay Krishna

In this work, we propose to study the utility of different meta-graphs, as well as how to simultaneously leverage multiple meta-graphs for HIN embedding in an unsupervised manner. Motivated by prolific research on homogeneous networks,…

Machine Learning · Computer Science 2019-10-02 Carl Yang , Yichen Feng , Pan Li , Yu Shi , Jiawei Han

Computational pathology models that use digitized histopathology whole-slide images have the potential to become a cost-effective and scalable alternative to molecular assays for the prediction of genomic biomarkers, a key task in precision…

Quantitative Methods · Quantitative Biology 2026-03-03 Ekaterina Redekop , Eric Zimmermann , Ava P Amini , Alex X Lu , Neil Tenenholtz , James Brian Hall , Lorin Crawford , Kristen A Severson

Humans possess a remarkable ability to integrate auditory and visual information, enabling a deeper understanding of the surrounding environment. This early fusion of audio and visual cues, demonstrated through cognitive psychology and…

Computer Vision and Pattern Recognition · Computer Science 2023-12-05 Shentong Mo , Pedro Morgado

Applying deep learning concepts from image detection and graph theory has greatly advanced protein-ligand binding affinity prediction, a challenge with enormous ramifications for both drug discovery and protein engineering. We build upon…

Biomolecules · Quantitative Biology 2023-12-05 Gregory W. Kyro , Rafael I. Brent , Victor S. Batista

Gaining insights into the structural and functional mechanisms of the brain has been a longstanding focus in neuroscience research, particularly in the context of understanding and treating neuropsychiatric disorders such as Schizophrenia…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Badhan Mazumder , Lei Wu , Vince D. Calhoun , Dong Hye Ye

In this paper, we propose a novel framework, Combo, for harmonious co-speech holistic 3D human motion generation and efficient customizable adaption. In particular, we identify that one fundamental challenge as the…

Computer Vision and Pattern Recognition · Computer Science 2025-09-22 Chao Xu , Mingze Sun , Zhi-Qi Cheng , Fei Wang , Yang Liu , Baigui Sun , Ruqi Huang , Alexander Hauptmann

Accurate prediction of compound-protein interactions (CPI) remains a cornerstone challenge in computational drug discovery. While existing sequence-based approaches leverage molecular fingerprints or graph representations, they critically…

Machine Learning · Computer Science 2025-04-08 Ngoc-Quang Nguyen

Naturally, humans use multiple modalities to convey information. The modalities are processed both sequentially and in parallel for communication in the human brain, this changes when humans interact with computers. Empowering computers…

Human-Computer Interaction · Computer Science 2020-06-09 Muhammad Zeeshan Baig , Manolya Kavakli

Improving hyperspectral image (HSI) semantic segmentation by exploiting complementary information from a supplementary data type (referred to X-modality) is promising but challenging due to differences in imaging sensors, image content, and…

Computer Vision and Pattern Recognition · Computer Science 2024-11-15 Xuming Zhang , Xingfa Gu , Qingjiu Tian , Lorenzo Bruzzone

The rapid growth of e-commerce has placed considerable pressure on customs representatives, prompting advanced methods. In tackling this, Artificial intelligence (AI) systems have emerged as a promising approach to minimize the risks faced.…

Software Engineering · Computer Science 2024-06-10 Otmane Amel , Sedrick Stassin , Sidi Ahmed Mahmoudi , Xavier Siebert

Recent advancements in the acquisition of various brain data sources have created new opportunities for integrating multimodal brain data to assist in early detection of complex brain disorders. However, current data integration approaches…

Image and Video Processing · Electrical Eng. & Systems 2023-05-26 Reza Shirkavand , Liang Zhan , Heng Huang , Li Shen , Paul M. Thompson

Vision foundation models (VFMs) are pre-trained on extensive image datasets to learn general representations for diverse types of data. These models can subsequently be fine-tuned for specific downstream tasks, significantly boosting…

Computer Vision and Pattern Recognition · Computer Science 2025-02-25 Shansong Wang , Mojtaba Safari , Qiang Li , Chih-Wei Chang , Richard LJ Qiu , Justin Roper , David S. Yu , Xiaofeng Yang

An effective pre-training framework with universal 3D representations is extremely desired in perceiving large-scale dynamic scenes. However, establishing such an ideal framework that is both task-generic and label-efficient poses a…

Computer Vision and Pattern Recognition · Computer Science 2024-05-14 Haoming Chen , Zhizhong Zhang , Yanyun Qu , Ruixin Zhang , Xin Tan , Yuan Xie

We propose a compact and effective framework to fuse multimodal features at multiple layers in a single network. The framework consists of two innovative fusion schemes. Firstly, unlike existing multimodal methods that necessitate…

Computer Vision and Pattern Recognition · Computer Science 2021-08-12 Yikai Wang , Fuchun Sun , Ming Lu , Anbang Yao

Ribonucleic acid (RNA) plays fundamental roles in biological systems, from carrying genetic information to performing enzymatic function. Understanding and designing RNA can enable novel therapeutic application and biotechnological…

Biomolecules · Quantitative Biology 2025-12-01 Dana Rubin , Allan dos Santos Costa , Manvitha Ponnapati , Joseph Jacobson

The Vision Transformer (ViT) has demonstrated remarkable performance in Self-Supervised Learning (SSL) for 3D medical image analysis. Masked AutoEncoder (MAE) for feature pre-training can further unleash the potential of ViT on various…

Computer Vision and Pattern Recognition · Computer Science 2025-01-13 Jiaxin Zhuang , Linshan Wu , Qiong Wang , Peng Fei , Varut Vardhanabhuti , Lin Luo , Hao Chen