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Acquiring plausible pathways on high-dimensional structural distributions is beneficial in several domains. For example, in the drug discovery field, a protein conformational pathway, i.e. a highly probable sequence of protein structural…

Quantitative Methods · Quantitative Biology 2025-06-04 Ziyad Oulhaj , Yoshiyuki Ishii , Kento Ohga , Kimihiro Yamazaki , Mutsuyo Wada , Yuhei Umeda , Takashi Kato , Yuichiro Wada , Hiroaki Kurihara

Topological data analysis (TDA) is an area of data science that focuses on using invariants from algebraic topology to provide multiscale shape descriptors for geometric data sets such as point clouds. One of the most important such…

Computational Geometry · Computer Science 2023-06-21 David Loiseaux , Mathieu Carrière , Andrew J. Blumberg

Topological data analysis aims to extract topological quantities from data, which tend to focus on the broader global structure of the data rather than local information. The Mapper method, specifically, generalizes clustering methods to…

Machine Learning · Computer Science 2019-10-22 Jacek Cyranka , Alexander Georges , David Meyer

Topological data analysis (TDA) is a rapidly evolving field in applied mathematics and data science that leverages tools from topology to uncover robust, shape-driven insights in complex datasets. The main workhorse is persistent homology,…

History and Overview · Mathematics 2025-07-29 Zhe Su , Xiang Liu , Layal Bou Hamdan , Vasileios Maroulas , Jie Wu , Gunnar Carlsson , Guo-Wei Wei

Topological data analysis is an emerging field that applies the study of topological invariants to data. Perhaps the simplest of these invariants is the number of connected components or clusters. In this work, we explore a topological…

Computational Geometry · Computer Science 2023-12-19 Ian Stewart Joyce , Grant Erdmann , Kirk P. Gardner , Ryan Kramer , Kyle Siegrist

Topological Data Analysis (TDA) is a discipline that applies algebraic topology techniques to analyze complex, multi-dimensional data. Although it is a relatively new field, TDA has been widely and successfully applied across various…

Machine Learning · Computer Science 2024-07-29 Martin Uray , Barbara Giunti , Michael Kerber , Stefan Huber

Topological Data Analysis (TDA) is a novel, and relatively new approach to analysing high-dimensional data sets. It does this by focussing on global properties like the shape and connectivity of the data giving it a significant advantage…

Instrumentation and Methods for Astrophysics · Physics 2019-04-26 Jeff Murugan , Duncan Robertson

Topological Data Analysis (TDA) is a novel statistical technique, particularly powerful for the analysis of large and high dimensional data sets. Much of TDA is based on the tool of persistent homology, represented visually via persistence…

Applications · Statistics 2017-11-07 Sarit Agami , Robert J. Adler

Topological data analysis (TDA) is a tool from data science and mathematics that is beginning to make waves in environmental science. In this work, we seek to provide an intuitive and understandable introduction to a tool from TDA that is…

Machine Learning · Computer Science 2025-07-15 Lander Ver Hoef , Henry Adams , Emily J. King , Imme Ebert-Uphoff

Topological Data Analysis (TDA) is an emergent field that aims to discover topological information hidden in a dataset. TDA tools have been commonly used to create filters and topological descriptors to improve Machine Learning (ML)…

Machine Learning · Computer Science 2022-02-07 Rolando Kindelan , José Frías , Mauricio Cerda , Nancy Hitschfeld

Topological Data Analysis (TDA) has emerged as a powerful framework for extracting robust, multiscale, and interpretable features from complex molecular data for artificial intelligence (AI) modeling and topological deep learning (TDL).…

Biomolecules · Quantitative Biology 2025-09-23 JunJie Wee , Jian Jiang

The Topological Data Analysis Ball Mapper (TDABM) algorithm of Dlotko (2019) provides a model free means to visualize multi-dimensional data. The visualizations are abstract two-dimensional representations of covers of the dataset. To…

Methodology · Statistics 2025-05-14 Simon Rudkin

Topological Data Analysis (TDA) can broadly be described as a collection of data analysis methods that find structure in data. This includes: clustering, manifold estimation, nonlinear dimension reduction, mode estimation, ridge estimation…

Methodology · Statistics 2016-09-28 Larry Wasserman

The utilization of statistical methods an their applications within the new field of study known as Topological Data Analysis has has tremendous potential for broadening our exploration and understanding of complex, high-dimensional data…

Applications · Statistics 2016-07-19 Patrick S. Medina , R. W. Doerge

High-dimensional data, characterized by many features, can be difficult to visualize effectively. Dimensionality reduction techniques, such as PCA, UMAP, and t-SNE, address this challenge by projecting the data into a lower-dimensional…

Topological methods can provide a way of proposing new metrics and methods of scrutinising data, that otherwise may be overlooked. In this work, a method of quantifying the shape of data, via a topic called topological data analysis will be…

Machine Learning · Statistics 2022-09-25 Tristan Gowdridge , Nikolaos Dervilis , Keith Worden

Choosing a suitable filtering function for the Mapper algorithm can be difficult due to its arbitrariness and domain-specific requirements. Finding a general filtering function that can be applied across domains is therefore of interest,…

Computational Geometry · Computer Science 2021-02-05 Filip Cornell

With the increasing use of black-box Machine Learning (ML) techniques in critical applications, there is a growing demand for methods that can provide transparency and accountability for model predictions. As a result, a large number of…

In recent years, techniques from Topological Data Analysis (TDA) have proven effective at capturing spatial features of multidimensional data. However, applying TDA to spatiotemporal data remains relatively underexplored. In this work, we…

Applications · Statistics 2025-09-30 Nicholas Bermingham , David White , Nathan Willey

Mapper is an unsupervised machine learning algorithm generalising the notion of clustering to obtain a geometric description of a dataset. The procedure splits the data into possibly overlapping bins which are then clustered. The output of…

Algebraic Topology · Mathematics 2019-06-05 Francisco Belchí , Jacek Brodzki , Matthew Burfitt , Mahesan Niranjan