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Recurrent neural networks (RNNs) are widely used throughout neuroscience as models of local neural activity. Many properties of single RNNs are well characterized theoretically, but experimental neuroscience has moved in the direction of…

Machine Learning · Computer Science 2023-01-31 Leo Kozachkov , Michaela Ennis , Jean-Jacques Slotine

Deep neural networks have proved to be a very effective way to perform classification tasks. They excel when the input data is high dimensional, the relationship between the input and the output is complicated, and the number of labeled…

Machine Learning · Computer Science 2017-11-28 Nicholas Frosst , Geoffrey Hinton

Deep neural networks are becoming more and more popular due to their revolutionary success in diverse areas, such as computer vision, natural language processing, and speech recognition. However, the decision-making processes of these…

Computation and Language · Computer Science 2021-10-15 Oana-Maria Camburu

Novel experimental techniques reveal the simultaneous activity of larger and larger numbers of neurons. As a result there is increasing interest in the structure of cooperative -- or correlated -- activity in neural populations, and in the…

Neurons and Cognition · Quantitative Biology 2015-05-30 James Trousdale , Yu Hu , Eric Shea-Brown , Krešimir Josić

It is largely believed that complex cognitive phenomena require the perfect orchestrated collaboration of many neurons. However, this is not what converging experimental evidence suggests. Single neurons, the so-called concept cells, may be…

Neurons and Cognition · Quantitative Biology 2019-12-05 Carlos Calvo Tapia , Ivan Tyukin , Valeri A. Makarov

Perceptions and actions, thoughts and memories result from coordinated activity in hundreds or even thousands of neurons in the brain. It is an old dream of the physics community to provide a statistical mechanics description for these and…

Disordered Systems and Neural Networks · Physics 2024-09-04 Leenoy Meshulam , William Bialek

Providing the neurobiological basis of information processing in higher animals, spiking neural networks must be able to learn a variety of complicated computations, including the generation of appropriate, possibly delayed reactions to…

Neurons and Cognition · Quantitative Biology 2016-06-30 Dominik Thalmeier , Marvin Uhlmann , Hilbert J. Kappen , Raoul-Martin Memmesheimer

Interpretability research often adopts a neuron-centric lens, treating individual neurons as the fundamental units of explanation. However, neuron-level explanations can be undermined by superposition, where single units respond to mixtures…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Julien Colin , Lore Goetschalckx , Thomas Fel , Victor Boutin , Thomas Serre , Nuria Oliver

Neurons communicate with downstream systems via sparse and incredibly brief electrical pulses, or spikes. Using these events, they control various targets such as neuromuscular units, neurosecretory systems, and other neurons in connected…

Neurons and Cognition · Quantitative Biology 2026-03-17 Paolo Agliati , André Urbano , Pablo Lanillos , Nasir Ahmad , Marcel van Gerven , Sander Keemink

Living systems, from single cells to higher vertebrates, receive a continuous stream of non-stationary inputs that they sense, e.g., via cell surface receptors or sensory organs. Integrating these time-varying, multi-sensory, and often…

Other Quantitative Biology · Quantitative Biology 2024-04-17 Daniel Koch , Akhilesh Nandan , Gayathri Ramesan , Aneta Koseska

An increasing body of evidence suggests that the trial-to-trial variability of spiking activity in the brain is not mere noise, but rather the reflection of a sampling-based encoding scheme for probabilistic computing. Since the precise…

Cortical neurons include many sub-cellular processes, operating at multiple timescales, which may affect their response to stimulation through non-linear and stochastic interaction with ion channels and ionic concentrations. Since new…

Neurons and Cognition · Quantitative Biology 2014-05-01 Daniel Soudry , Ron Meir

The brain effortlessly extracts latent causes of stimuli, but how it does this at the network level remains unknown. Most prior attempts at this problem proposed neural networks that implement independent component analysis which works…

Signal Processing · Electrical Eng. & Systems 2023-04-11 Bariscan Bozkurt , Ates Isfendiyaroglu , Cengiz Pehlevan , Alper T. Erdogan

Physics perfectly describes neuronal operation, provided that we take into account that biology uses slow, positively charged ions rather than electrons as charge carriers and remove untested ad hoc hypotheses that contradict science's…

Biological Physics · Physics 2026-04-13 János Végh

Intrinsic brain activity is characterized by highly structured co-activations between different regions, whose origin is still under debate. In this paper, we address the question whether it is possible to unveil how the underlying…

The continuous integration of experimental data into coherent models of the brain is an increasing challenge of modern neuroscience. Such models provide a bridge between structure and activity, and identify the mechanisms giving rise to…

Neurons and Cognition · Quantitative Biology 2017-03-03 Jannis Schuecker , Maximilian Schmidt , Sacha J. van Albada , Markus Diesmann , Moritz Helias

One of the defining features of living systems is their adaptability to changing environmental conditions. This requires organisms to extract temporal and spatial features of their environment, and use that information to compute the…

Neurons and Cognition · Quantitative Biology 2024-02-27 Maria Sol Vidal-Saez , Oscar Vilarroya , Jordi Garcia-Ojalvo

The fields of neural computation and artificial neural networks have developed much in the last decades. Most of the works in these fields focus on implementing and/or learning discrete functions or behavior. However, technical, physical,…

Neural and Evolutionary Computing · Computer Science 2016-06-15 Frieder Stolzenburg , Florian Ruh

Neural networks are composed of neurons and synapses, which are responsible for learning in a slow adaptive dynamical process. Here we experimentally show that neurons act like independent anisotropic multiplex hubs, which relay and mute…

Neurons and Cognition · Quantitative Biology 2017-07-21 Roni Vardi , Amir Goldental , Anton Sheinin , Shira Sardi , Ido Kanter

We show how brain networks, modeled as Spiking Neural Networks, can be viewed at different levels of abstraction. Lower levels include complications such as failures of neurons and edges. Higher levels are more abstract, making simplifying…

Neural and Evolutionary Computing · Computer Science 2024-08-06 Nancy Lynch