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Interpretability is one of the considerations when applying machine learning to high-stakes fields such as healthcare that involve matters of life safety. Generalized Additive Models (GAMs) enhance interpretability by visualizing shape…

Machine Learning · Computer Science 2025-10-06 Fumin Wang

This paper addresses the problem of identifying and estimating the causal effect of a treatment in the presence of unmeasured confounding and various types of right-censoring. Examples of these censoring mechanisms are administrative…

Statistics Theory · Mathematics 2025-03-19 Ilias Willems , Sara Rutten , Gilles Crommen , Ingrid Van Keilegom

Estimating the Individual Treatment Effect from observational data, defined as the difference between outcomes with and without treatment or intervention, while observing just one of both, is a challenging problems in causal learning. In…

Machine Learning · Computer Science 2020-05-07 Céline Beji , Michaël Bon , Florian Yger , Jamal Atif

Unmeasured confounding and selection bias are often of concern in observational studies and may invalidate a causal analysis if not appropriately accounted for. Under outcome-dependent sampling, a latent factor that has causal effects on…

Methodology · Statistics 2022-08-03 Kendrick Qijun Li , Xu Shi , Wang Miao , Eric Tchetgen Tchetgen

The Mallows model occupies a central role in parametric modelling of ranking data to learn preferences of a population of judges. Despite the wide range of metrics for rankings that can be considered in the model specification, the choice…

Methodology · Statistics 2022-09-21 Marta Crispino , Cristina Mollica , Valerio Astuti , Luca Tardella

Evaluating the effects of time-varying exposures is essential for longitudinal studies. The effect estimation becomes increasingly challenging when dealing with hundreds of time-dependent confounders. We propose a Marginal Structure…

Methodology · Statistics 2025-10-21 Zhiwei Zhao , Chixiang Chen , Shuo Chen

Causal inference with observational studies often relies on the assumptions of unconfoundedness and overlap of covariate distributions in different treatment groups. The overlap assumption is violated when some units have propensity scores…

Methodology · Statistics 2022-07-19 Shu Yang , Peng Ding

Although most pregnancies result in a good outcome, complications are not uncommon and can be associated with serious implications for mothers and babies. Predictive modeling has the potential to improve outcomes through better…

Machine Learning · Computer Science 2023-10-18 Tomas M. Bosschieter , Zifei Xu , Hui Lan , Benjamin J. Lengerich , Harsha Nori , Ian Painter , Vivienne Souter , Rich Caruana

Controlled Direct Effect (CDE) is one of the causal estimands used to evaluate both exposure and mediation effects on an outcome. When there are unmeasured confounders existing between the mediator and the outcome, the ordinary…

Methodology · Statistics 2024-10-30 Shunichiro Orihara , Shinpei Imori , Kosuke Morikawa , Atsushi Goto , Masataka Taguri

Two problems that arise in making causal inferences for non-mortality outcomes such as bronchopulmonary dysplasia (BPD) are unmeasured confounding and censoring by death, i.e., the outcome is only observed when subjects survive. In…

Methodology · Statistics 2018-02-20 Kwonsang Lee , Scott A. Lorch , Dylan S. Small

Data-driven methods for personalizing treatment assignment have garnered much attention from clinicians and researchers. Dynamic treatment regimes formalize this through a sequence of decision rules that map individual patient…

Methodology · Statistics 2022-02-22 Eric J. Rose , Erica E. M. Moodie , Susan Shortreed

Treatment-induced confounders complicate analyses of time-varying treatment effects and causal mediation. Conditioning on these variables naively to estimate marginal effects may inappropriately block causal pathways and may induce spurious…

Applications · Statistics 2018-08-24 Geoffrey T. Wodtke , Zahide Alaca , Xiang Zhou

How to include censored data in a statistical analysis is a recur-rent issue in statistics. In multivariate extremes, the dependence structure of large observations can be characterized in terms of a non parametric angular measure, while…

Methodology · Statistics 2014-12-03 Anne Sabourin

A major limitation of machine learning (ML) prediction models is that they recover associational, rather than causal, predictive relationships between variables. In high-stakes automation applications of ML this is problematic, as the model…

Machine Learning · Computer Science 2025-11-04 Jianqiao Mao , Max A. Little

Mediation analysis assesses the extent to which the exposure affects the outcome indirectly through a mediator and the extent to which it operates directly through other pathways. The popular Baron-Kenny approach estimates the indirect and…

Methodology · Statistics 2025-04-08 Mingrui Zhang , Peng Ding

When drawing causal inferences about the effects of multiple treatments on clustered survival outcomes using observational data, we need to address implications of the multilevel data structure, multiple treatments, censoring and unmeasured…

Methodology · Statistics 2022-02-18 Liangyuan Hu , Jiayi Ji , Ronald D. Ennis , Joseph W. Hogan

We extend our previous work on sensitivity analysis for the risk ratio and difference contrasts under unmeasured confounding to any contrast. We prove that the bounds produced are still arbitrarily sharp, i.e. practically attainable. We…

Methodology · Statistics 2024-06-13 Jose M. Peña

Multi-modal semantic segmentation (MMSS) addresses the limitations of single-modality data by integrating complementary information across modalities. Despite notable progress, a significant gap persists between research and real-world…

Computer Vision and Pattern Recognition · Computer Science 2025-04-11 Chenfei Liao , Kaiyu Lei , Xu Zheng , Junha Moon , Zhixiong Wang , Yixuan Wang , Danda Pani Paudel , Luc Van Gool , Xuming Hu

Causal decomposition analysis aims to assess the effect of modifying risk factors on reducing social disparities in outcomes. Recently, this analysis has incorporated individual characteristics when modifying risk factors by utilizing…

Machine Learning · Statistics 2025-09-16 Soojin Park , Suyeon Kang , Chioun Lee

Causal inference from observational data provides strong evidence for the best action in decision-making without performing expensive randomized trials. The effect of an action is usually not identifiable under unobserved confounding, even…

Machine Learning · Computer Science 2026-02-02 Md Musfiqur Rahman , Ziwei Jiang , Hilaf Hasson , Murat Kocaoglu