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Myocardial infarction (MI) is a leading cause of death, and its adverse outcomes are urgent to predict. Yet ECG-based prognostic models underperform because deep learning requires large, labelled datasets, which are scarce in medicine.…

One third of stroke survivors have language difficulties. Emerging evidence suggests that their likelihood of recovery depends mainly on the damage to language centers. Thus previous research for predicting language recovery post-stroke has…

Computer Vision and Pattern Recognition · Computer Science 2018-11-28 Yusuf H. Roohani , Noor Sajid , Pranava Madhyastha , Cathy J. Price , Thomas M. H. Hope

Parkinson's disease (PD) is a neurodegenerative disorder characterized by motor dysfunction and abnormal neural oscillations. These symptoms can be modulated through electrical stimulation. Traditional neural activity analysis in PD has…

Neurons and Cognition · Quantitative Biology 2025-02-19 Jibum Kim , Hanseul Choi , Gaeun Kim , Sunggu Yang , Eunha Baeg , Donggue Kim , Seongwon Jin , Sangwon Byun

Drug repositioning holds great promise because it can reduce the time and cost of new drug development. While drug repositioning can omit various R&D processes, confirming pharmacological effects on biomolecules is essential for application…

Machine Learning · Computer Science 2022-12-29 Atsuko Takagi , Mayumi Kamada , Eri Hamatani , Ryosuke Kojima , Yasushi Okuno

Stroke is a major cause of death and permanent impairment, making it a major worldwide health concern. For prompt intervention and successful preventative tactics, early risk assessment is essential. To address this challenge, we used…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 A S M Ahsanul Sarkar Akib , Raduana Khawla , Abdul Hasib

The brain continually reorganizes its functional network to adapt to post-stroke functional impairments. Previous studies using static modularity analysis have presented global-level behavior patterns of this network reorganization.…

Computation · Statistics 2024-03-25 Kaichao Wu , Beth Jelfs , Katrina Neville , Wenzhen He , Qiang Fang

Post-stroke MRI not only delineates focal lesions but also reveals secondary structural changes, such as atrophy and ventricular enlargement. These abnormalities, increasingly recognised as imaging biomarkers of recovery and outcome, remain…

Computer Vision and Pattern Recognition · Computer Science 2025-10-29 Youwan Mahé , Elise Bannier , Stéphanie Leplaideur , Elisa Fromont , Francesca Galassi

Stroke is a common disabling neurological condition that affects about one-quarter of the adult population over age 25; more than half of patients still have poor outcomes, such as permanent functional dependence or even death, after the…

Computer Vision and Pattern Recognition · Computer Science 2024-02-19 Chia-Ling Tsai , Hui-Yun Su , Shen-Feng Sung , Wei-Yang Lin , Ying-Ying Su , Tzu-Hsien Yang , Man-Lin Mai

Background: Stroke is second-leading cause of disability and death among adults. Approximately 17 million people suffer from a stroke annually, with about 85% being ischemic strokes. Predicting mortality of ischemic stroke patients in…

Machine Learning · Computer Science 2024-09-04 Armin Abdollahi , Negin Ashrafi , Maryam Pishgar

A longstanding challenge surrounding deep learning algorithms is unpacking and understanding how they make their decisions. Explainable Artificial Intelligence (XAI) offers methods to provide explanations of internal functions of algorithms…

Artificial Intelligence · Computer Science 2022-08-16 Amin Nayebi , Sindhu Tipirneni , Brandon Foreman , Chandan K. Reddy , Vignesh Subbian

Statistical techniques are needed to analyse data structures with complex dependencies such that clinically useful information can be extracted. Individual-specific networks, which capture dependencies in complex biological systems, are…

Methodology · Statistics 2023-08-30 Mariella Gregorich , Sean L. Simpson , Georg Heinze

In the field of eXplainable AI (XAI), robust "blackbox" algorithms such as Convolutional Neural Networks (CNNs) are known for making high prediction performance. However, the ability to explain and interpret these algorithms still require…

Machine Learning · Computer Science 2021-11-25 Shaw-Hwa Lo , Yiqiao Yin

In this study, we utilized statistical analysis and machine learning methods to examine whether rehabilitation exercises can improve patients post-stroke functional abilities, as well as forecast the improvement in functional abilities. Our…

This study explored the potential of gait analysis as a tool for assessing post-injury complications, e.g., infection, malunion, or hardware irritation, in patients with lower extremity fractures. The research focused on the proficiency of…

Machine Learning · Computer Science 2023-09-29 Mostafa Rezapour , Rachel B. Seymour , Stephen H. Sims , Madhav A. Karunakar , Nahir Habet , Metin Nafi Gurcan

Stroke classification remains challenging due to variations in writing style, ambiguous content, and dynamic writing positions. The core challenge in stroke classification is modeling the semantic relationships between strokes. Our…

Computer Vision and Pattern Recognition · Computer Science 2025-12-09 Yiheng Huang , Shuang She , Zewei Wei , Jianmin Lin , Ming Yang , Wenyin Liu

Predicting stroke risk is a complex challenge that can be enhanced by integrating diverse clinically available data modalities. This study introduces a self-supervised multimodal framework that combines 3D brain imaging, clinical data, and…

Computer Vision and Pattern Recognition · Computer Science 2025-07-09 Camille Delgrange , Olga Demler , Samia Mora , Bjoern Menze , Ezequiel de la Rosa , Neda Davoudi

Stroke is widely considered as the second most common cause of mortality. The adverse consequences of stroke have led to global interest and work for improving the management and diagnosis of stroke. Various techniques for data mining have…

Machine Learning · Computer Science 2021-10-22 Muhammad Salman Pathan , Jianbiao Zhang , Deepu John , Avishek Nag , Soumyabrata Dev

Stroke is a major global health problem that causes mortality and morbidity. Predicting the outcomes of stroke intervention can facilitate clinical decision-making and improve patient care. Engaging and developing deep learning techniques…

Image and Video Processing · Electrical Eng. & Systems 2024-12-09 Zeynel A. Samak , Philip Clatworthy , Majid Mirmehdi

Functional connections in the brain are frequently represented by weighted networks, with nodes representing locations in the brain, and edges representing the strength of connectivity between these locations. One challenge in analyzing…

Applications · Statistics 2022-09-28 Yura Kim , Daniel Kessler , Elizaveta Levina

This study addresses the challenges of symptom evolution complexity and insufficient temporal dependency modeling in Parkinson's disease progression prediction. It proposes a unified prediction framework that integrates structural…

Machine Learning · Computer Science 2025-08-22 Jiacheng Hu , Bo Zhang , Ting Xu , Haifeng Yang , Min Gao