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The proliferation of Large Language Models (LLMs) in medicine has enabled impressive capabilities, yet a critical gap remains in their ability to perform systematic, transparent, and verifiable reasoning, a cornerstone of clinical practice.…

Computation and Language · Computer Science 2025-08-04 Wenxuan Wang , Zizhan Ma , Meidan Ding , Shiyi Zheng , Shengyuan Liu , Jie Liu , Jiaming Ji , Wenting Chen , Xiang Li , Linlin Shen , Yixuan Yuan

Recent advancements in Large Language Models (LLMs) have demonstrated significant promise in clinical diagnosis. However, current models struggle to emulate the iterative, diagnostic hypothesis-driven reasoning of real clinical scenarios.…

Computation and Language · Computer Science 2026-01-06 Qipeng Wang , Rui Sheng , Yafei Li , Huamin Qu , Yushi Sun , Min Zhu

Misdiagnosis causes significant harm to healthcare systems worldwide, leading to increased costs and patient risks. MedRAG is a smart multimodal healthcare copilot equipped with powerful large language model (LLM) reasoning, designed to…

Artificial Intelligence · Computer Science 2025-06-04 Xuejiao Zhao , Siyan Liu , Su-Yin Yang , Chunyan Miao

With the widespread application of electroencephalography (EEG) in neuroscience and clinical practice, efficiently retrieving and semantically interpreting large-scale, multi-source, heterogeneous EEG data has become a pressing challenge.…

Computation and Language · Computer Science 2025-10-14 Yi Wang , Haoran Luo , Lu Meng , Ziyu Jia , Xinliang Zhou , Qingsong Wen

Purpose: Large Language Models (LLMs) hold significant promise for medical applications. Retrieval Augmented Generation (RAG) emerges as a promising approach for customizing domain knowledge in LLMs. This case study presents the development…

Recently, Retrieval-Augmented Generation (RAG) has achieved remarkable success in addressing the challenges of Large Language Models (LLMs) without necessitating retraining. By referencing an external knowledge base, RAG refines LLM…

Artificial Intelligence · Computer Science 2024-09-11 Boci Peng , Yun Zhu , Yongchao Liu , Xiaohe Bo , Haizhou Shi , Chuntao Hong , Yan Zhang , Siliang Tang

Large language models (LLMs) struggle with relation completion (RC), both with and without retrieval-augmented generation (RAG), particularly when the required information is rare or sparsely represented. To address this, we propose a novel…

Computation and Language · Computer Science 2026-04-27 Fahmida Alam , Mihai Surdeanu , Ellen Riloff

Clinical diagnosis is a highly specialized discipline requiring both domain expertise and strict adherence to rigorous guidelines. While current AI-driven medical research predominantly focuses on knowledge graphs or natural text…

Machine Learning · Computer Science 2025-12-12 Haolin Li , Tianjie Dai , Zhe Chen , Siyuan Du , Jiangchao Yao , Ya Zhang , Yanfeng Wang

Retrieval-augmented generation (RAG) has proven highly effective in improving large language models (LLMs) across various domains. However, there is no benchmark specifically designed to assess the effectiveness of RAG in the legal domain,…

Computation and Language · Computer Science 2025-03-03 Haitao Li , Yifan Chen , Yiran Hu , Qingyao Ai , Junjie Chen , Xiaoyu Yang , Jianhui Yang , Yueyue Wu , Zeyang Liu , Yiqun Liu

Retrieval-Augmented Generation (RAG) represents a major advancement in natural language processing (NLP), combining large language models (LLMs) with information retrieval systems to enhance factual grounding, accuracy, and contextual…

Computation and Language · Computer Science 2025-07-28 Agada Joseph Oche , Ademola Glory Folashade , Tirthankar Ghosal , Arpan Biswas

Retrieval-augmented generation (RAG) is a framework enabling large language models (LLMs) to enhance their accuracy and reduce hallucinations by integrating external knowledge bases. In this paper, we introduce a hybrid RAG system enhanced…

Computation and Language · Computer Science 2024-09-04 Ye Yuan , Chengwu Liu , Jingyang Yuan , Gongbo Sun , Siqi Li , Ming Zhang

Large Language Models (LLMs) have significantly enhanced conversational Artificial Intelligence(AI) chatbots; however, domain-specific accuracy and the avoidance of factual inconsistencies remain pressing challenges, particularly for large…

Information Retrieval · Computer Science 2025-09-24 Olalekan K. Akindele , Bhupesh Kumar Mishra , Kenneth Y. Wertheim

Large language models (LLMs) frequently generate confident yet factually incorrect content when used for language generation (a phenomenon often known as hallucination). Retrieval augmented generation (RAG) tries to reduce factual errors by…

Information Retrieval · Computer Science 2026-04-01 Dobrik Georgiev , Kheeran Naidu , Alberto Cattaneo , Federico Monti , Carlo Luschi , Daniel Justus

The increasing complexity of clinical decision-making, alongside the rapid expansion of electronic health records (EHR), presents both opportunities and challenges for delivering data-informed care. This paper proposes a clinical decision…

Artificial Intelligence · Computer Science 2025-10-03 Leon Garza , Anantaa Kotal , Michael A. Grasso , Emre Umucu

Graph-based retrieval-augmented generation (RAG) enriches large language models (LLMs) with external knowledge for long-context understanding and multi-hop reasoning, but existing methods face a granularity dilemma: fine-grained…

Computation and Language · Computer Science 2025-09-26 Yaxiong Wu , Jianyuan Bo , Yongyue Zhang , Sheng Liang , Yong Liu

Retrieval-Augmented Generation (RAG) has recently demonstrated the performance of Large Language Models (LLMs) in the knowledge-intensive tasks such as Question-Answering (QA). RAG expands the query context by incorporating external…

Machine Learning · Computer Science 2024-06-18 Zijian Hei , Weiling Liu , Wenjie Ou , Juyi Qiao , Junming Jiao , Guowen Song , Ting Tian , Yi Lin

Large Language Models (LLMs) have shown remarkable progress in medical question answering (QA), yet their effectiveness remains predominantly limited to English due to imbalanced multilingual training data and scarce medical resources for…

Retrieval Augmented Generation (RAG) complements the knowledge of Large Language Models (LLMs) by leveraging external information to enhance response accuracy for queries. This approach is widely applied in several fields by taking its…

Despite significant advancements in adapting Large Language Models (LLMs) for radiology report generation (RRG), clinical adoption remains challenging due to difficulties in accurately mapping pathological and anatomical features to their…

Computer Vision and Pattern Recognition · Computer Science 2025-08-22 Qilong Xing , Zikai Song , Youjia Zhang , Na Feng , Junqing Yu , Wei Yang

Although the Retrieval-Augmented Generation (RAG) paradigms can use external knowledge to enhance and ground the outputs of Large Language Models (LLMs) to mitigate generative hallucinations and static knowledge base problems, they still…

Computation and Language · Computer Science 2024-05-24 Diji Yang , Jinmeng Rao , Kezhen Chen , Xiaoyuan Guo , Yawen Zhang , Jie Yang , Yi Zhang
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