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Topological data analyses are rapidly turning into key tools for quantifying large volumes of neurobiological data, e.g., for organizing the spiking outputs of large neuronal ensembles and thus gaining insights into the information produced…

Neurons and Cognition · Quantitative Biology 2019-09-18 Yuri Dabaghian

In this paper, we develop an approach to modeling high-dimensional networks with a large number of nodes arranged in a hierarchical and modular structure. We propose a novel multi-scale factor analysis (MSFA) model which partitions the…

Applications · Statistics 2020-04-10 Chee-Ming Ting , Hernando Ombao , Sh-Hussain Salleh

The exponential rise in data generation has led to vast, heterogeneous datasets crucial for predictive analytics and decision-making. Ensuring data quality and semantic integrity remains a challenge. This paper presents a brain-inspired…

Machine Learning · Computer Science 2025-03-06 Ashwin Viswanathan Kannan , Johnson P Thomas , Abhimanyu Mukerji

Functional subnetwork extraction is commonly used to explore the brain's modular structure. However, reliable subnetwork extraction from functional magnetic resonance imaging (fMRI) data remains challenging due to the pronounced noise in…

Neurons and Cognition · Quantitative Biology 2018-01-17 Chendi Wang , Rafeef Abugharbieh

Traditional Topological Data Analysis (TDA) methods, such as Persistent Homology (PH), rely on distance measures (e.g., cross-correlation, partial correlation, coherence, and partial coherence) that are symmetric by definition. While useful…

Neurons and Cognition · Quantitative Biology 2024-07-19 Anass B. El-Yaagoubi , Moo K. Chung , Hernando Ombao

Graph Neural Networks (GNNs) excel at learning from pairwise interactions but often overlook multi-way and hierarchical relationships. Topological Deep Learning (TDL) addresses this limitation by leveraging combinatorial topological spaces.…

Due to their ability to model meaningful higher order relations among a set of entities, higher order network models have emerged recently as a powerful alternative for graph-based network models which are only capable of modeling binary…

Machine Learning · Computer Science 2023-12-20 Karthikeyan Natesan Ramamurthy , Aldo Guzmán-Sáenz , Mustafa Hajij

Topological techniques have become a popular tool for studying information flows in neural networks. In particular, simplicial homology theory is used to analyze how cognitive representations of space emerge from large conglomerates of…

Neurons and Cognition · Quantitative Biology 2025-02-19 Andrey Babichev , Vladimir Vashin , Yuri Dabaghian

Hypergraph structure learning, which aims to learn the hypergraph structures from the observed signals to capture the intrinsic high-order relationships among the entities, becomes crucial when a hypergraph topology is not readily available…

Machine Learning · Computer Science 2025-03-12 Bohan Tang , Siheng Chen , Xiaowen Dong

Brain graph super-resolution (SR) is an under-explored yet highly relevant task in network neuroscience. It circumvents the need for costly and time-consuming medical imaging data collection, preparation, and processing. Current SR methods…

Machine Learning · Computer Science 2024-11-06 Pragya Singh , Islem Rekik

Networks in nature have complex interactions among agents. One significant phenomenon induced by interactions is synchronization of coupled agents, and the interactive network topology can be tuned to optimize synchronization. The previous…

Physics and Society · Physics 2021-08-26 Ying Tang , Dinghua Shi , Linyuan Lü

We propose a framework for constructing combinatorial complexes (CCs) from fMRI time series data that captures both pairwise and higher-order neural interactions through information-theoretic measures, bridging topological deep learning and…

Neurons and Cognition · Quantitative Biology 2026-01-06 Valentina Sánchez , Çiçek Güven , Koen Haak , Theodore Papamarkou , Gonzalo Nápoles , Marie Šafář Postma

Networks are a fundamental tool for understanding and modeling complex systems in physics, biology, neuroscience, engineering, and social science. Many networks are known to exhibit rich, lower-order connectivity patterns that can be…

Social and Information Networks · Computer Science 2018-01-08 Austin R. Benson , David F. Gleich , Jure Leskovec

With recent advancements in non-invasive techniques for measuring brain activity, such as magnetic resonance imaging (MRI), the study of structural and functional brain networks through graph signal processing (GSP) has gained notable…

Machine Learning · Computer Science 2025-11-13 Martín Schmidt , Sara Silva , Federico Larroca , Gonzalo Mateos , Pablo Musé

A social interaction (so-called higher-order event/interaction) can be regarded as the activation of the hyperlink among the corresponding individuals. Social interactions can be, thus, represented as higher-order temporal networks, that…

Physics and Society · Physics 2024-08-12 H. A. Bart Peters , Alberto Ceria , Huijuan Wang

Topological data analysis (TDA) has become a powerful approach over the last twenty years, mainly due to its ability to capture the shape and the geometry inherent in the data. Persistence homology, which is a particular tool in TDA, has…

Neurons and Cognition · Quantitative Biology 2024-01-12 Anass B. El-Yaagoubi , Shuhao Jiao , Moo K. Chung , Hernando Ombao

The brain is a paradigmatic example of a complex system as its functionality emerges as a global property of local mesoscopic and microscopic interactions. Complex network theory allows to elicit the functional architecture of the brain in…

Neurons and Cognition · Quantitative Biology 2017-01-18 Rossana Mastrandrea , Andrea Gabrielli , Fabrizio Piras , Gianfranco Spalletta , Guido Caldarelli , Tommaso Gili

Recently, there has been increased interest in fusing multimodal imaging to better understand brain organization. Specifically, accounting for knowledge of anatomical pathways connecting brain regions should lead to desirable outcomes such…

Applications · Statistics 2018-03-02 Ixavier A. Higgins , Suprateek Kundu , Ying Guo

Winner Take All (WTA) circuits a type of Spiking Neural Networks (SNN) have been suggested as facilitating the brain's ability to process information in a Bayesian manner. Research has shown that WTA circuits are capable of approximating…

Artificial Intelligence · Computer Science 2023-08-30 Otto van der Himst , Leila Bagheriye , Johan Kwisthout

One of the key challenges in many research fields is uncovering how different interconnected systems interact within complex networks, typically represented as multi-layer networks. Capturing the intra- and cross-layer interactions among…

Signal Processing · Electrical Eng. & Systems 2025-10-13 Stefania Sardellitti , Breno C. Bispo , Fernando A. N. Santos , Juliano B. Lima