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Deep learning models usually require sufficient training data to achieve high accuracy, but obtaining labeled data can be time-consuming and labor-intensive. Here we introduce a template-based training method to train a 3D U-Net model from…

Image and Video Processing · Electrical Eng. & Systems 2023-08-07 Fang-Cheng Yeh

Prognoses of Traumatic Brain Injury (TBI) outcomes are neither easily nor accurately determined from clinical indicators. This is due in part to the heterogeneity of damage inflicted to the brain, ultimately resulting in diverse and complex…

The 2024 Brain Tumor Segmentation Meningioma Radiotherapy (BraTS-MEN-RT) challenge aimed to advance automated segmentation algorithms using the largest known multi-institutional dataset of 750 radiotherapy planning brain MRIs with…

Computer Vision and Pattern Recognition · Computer Science 2025-07-23 Dominic LaBella , Valeriia Abramova , Mehdi Astaraki , Andre Ferreira , Zhifan Jiang , Mason C. Cleveland , Ramandeep Kang , Uma M. Lal-Trehan Estrada , Cansu Yalcin , Rachika E. Hamadache , Clara Lisazo , Adrià Casamitjana , Joaquim Salvi , Arnau Oliver , Xavier Lladó , Iuliana Toma-Dasu , Tiago Jesus , Behrus Puladi , Jens Kleesiek , Victor Alves , Jan Egger , Daniel Capellán-Martín , Abhijeet Parida , Austin Tapp , Xinyang Liu , Maria J. Ledesma-Carbayo , Jay B. Patel , Thomas N. McNeal , Maya Viera , Owen McCall , Albert E. Kim , Elizabeth R. Gerstner , Christopher P. Bridge , Katherine Schumacher , Michael Mix , Kevin Leu , Shan McBurney-Lin , Pierre Nedelec , Javier Villanueva-Meyer , David R. Raleigh , Jonathan Shapey , Tom Vercauteren , Kazumi Chia , Marina Ivory , Theodore Barfoot , Omar Al-Salihi , Justin Leu , Lia M. Halasz , Yuri S. Velichko , Chunhao Wang , John P. Kirkpatrick , Scott R. Floyd , Zachary J. Reitman , Trey C. Mullikin , Eugene J. Vaios , Christina Huang , Ulas Bagci , Sean Sachdev , Jona A. Hattangadi-Gluth , Tyler M. Seibert , Nikdokht Farid , Connor Puett , Matthew W. Pease , Kevin Shiue , Syed Muhammad Anwar , Shahriar Faghani , Peter Taylor , Pranav Warman , Jake Albrecht , András Jakab , Mana Moassefi , Verena Chung , Rong Chai , Alejandro Aristizabal , Alexandros Karargyris , Hasan Kassem , Sarthak Pati , Micah Sheller , Nazanin Maleki , Rachit Saluja , Florian Kofler , Christopher G. Schwarz , Philipp Lohmann , Phillipp Vollmuth , Louis Gagnon , Maruf Adewole , Hongwei Bran Li , Anahita Fathi Kazerooni , Nourel Hoda Tahon , Udunna Anazodo , Ahmed W. Moawad , Bjoern Menze , Marius George Linguraru , Mariam Aboian , Benedikt Wiestler , Ujjwal Baid , Gian-Marco Conte , Andreas M. Rauschecker , Ayman Nada , Aly H. Abayazeed , Raymond Huang , Maria Correia de Verdier , Jeffrey D. Rudie , Spyridon Bakas , Evan Calabrese

Brain tumour segmentation plays a key role in computer-assisted surgery. Deep neural networks have increased the accuracy of automatic segmentation significantly, however these models tend to generalise poorly to different imaging…

Computer Vision and Pattern Recognition · Computer Science 2017-09-06 Lucas Fidon , Wenqi Li , Luis C. Garcia-Peraza-Herrera , Jinendra Ekanayake , Neil Kitchen , Sebastien Ourselin , Tom Vercauteren

Accurate thalamic nuclei segmentation is crucial for understanding neurological diseases, brain functions, and guiding clinical interventions. However, the optimal inputs for segmentation remain unclear. This study systematically evaluates…

Image and Video Processing · Electrical Eng. & Systems 2025-08-19 Anqi Feng , Zhangxing Bian , Samuel W. Remedios , Savannah P. Hays , Blake E. Dewey , Jiachen Zhuo , Dan Benjamini , Jerry L. Prince

Automating Multiple Sclerosis (MS) lesion segmentation would be of great benefit in initial diagnosis as well as monitoring disease progression. Deep learning based segmentation models perform well in many domains, but the state-of-the-art…

Image and Video Processing · Electrical Eng. & Systems 2024-10-28 Liviu Badea , Maria Popa

Sub-cortical brain structure segmentation in Magnetic Resonance Images (MRI) has attracted the interest of the research community for a long time because morphological changes in these structures are related to different neurodegenerative…

Computer Vision and Pattern Recognition · Computer Science 2018-11-15 Kaisar Kushibar , Sergi Valverde , Sandra Gonzalez-Villa , Jose Bernal , Mariano Cabezas , Arnau Oliver , Xavier Llado

Gliomas are the most common malignant primary brain tumors in adults and one of the deadliest types of cancer. There are many challenges in treatment and monitoring due to the genetic diversity and high intrinsic heterogeneity in…

Computer Vision and Pattern Recognition · Computer Science 2024-05-29 Maria Correia de Verdier , Rachit Saluja , Louis Gagnon , Dominic LaBella , Ujjwall Baid , Nourel Hoda Tahon , Martha Foltyn-Dumitru , Jikai Zhang , Maram Alafif , Saif Baig , Ken Chang , Gennaro D'Anna , Lisa Deptula , Diviya Gupta , Muhammad Ammar Haider , Ali Hussain , Michael Iv , Marinos Kontzialis , Paul Manning , Farzan Moodi , Teresa Nunes , Aaron Simon , Nico Sollmann , David Vu , Maruf Adewole , Jake Albrecht , Udunna Anazodo , Rongrong Chai , Verena Chung , Shahriar Faghani , Keyvan Farahani , Anahita Fathi Kazerooni , Eugenio Iglesias , Florian Kofler , Hongwei Li , Marius George Linguraru , Bjoern Menze , Ahmed W. Moawad , Yury Velichko , Benedikt Wiestler , Talissa Altes , Patil Basavasagar , Martin Bendszus , Gianluca Brugnara , Jaeyoung Cho , Yaseen Dhemesh , Brandon K. K. Fields , Filip Garrett , Jaime Gass , Lubomir Hadjiiski , Jona Hattangadi-Gluth , Christopher Hess , Jessica L. Houk , Edvin Isufi , Lester J. Layfield , George Mastorakos , John Mongan , Pierre Nedelec , Uyen Nguyen , Sebastian Oliva , Matthew W. Pease , Aditya Rastogi , Jason Sinclair , Robert X. Smith , Leo P. Sugrue , Jonathan Thacker , Igor Vidic , Javier Villanueva-Meyer , Nathan S. White , Mariam Aboian , Gian Marco Conte , Anders Dale , Mert R. Sabuncu , Tyler M. Seibert , Brent Weinberg , Aly Abayazeed , Raymond Huang , Sevcan Turk , Andreas M. Rauschecker , Nikdokht Farid , Philipp Vollmuth , Ayman Nada , Spyridon Bakas , Evan Calabrese , Jeffrey D. Rudie

Brain MR image segmentation is a key task in neuroimaging studies. It is commonly conducted using standard computational tools, such as FSL, SPM, multi-atlas segmentation etc, which are often registration-based and suffer from expensive…

Image and Video Processing · Electrical Eng. & Systems 2019-08-29 Chengliang Dai , Yuanhan Mo , Elsa Angelini , Yike Guo , Wenjia Bai

The segmentation of diseases is a popular topic explored by researchers in the field of machine learning. Brain tumors are extremely dangerous and require the utmost precision to segment for a successful surgery. Patients with tumors…

Image and Video Processing · Electrical Eng. & Systems 2022-04-05 Sanskriti Singh

Cortical lesions (CLs) have emerged as valuable biomarkers in multiple sclerosis (MS), offering high diagnostic specificity and prognostic relevance. However, their routine clinical integration remains limited due to subtle magnetic…

Medical image segmentation being a substantial component of image processing plays a significant role to analyze gross anatomy, to locate an infirmity and to plan the surgical procedures. Segmentation of brain Magnetic Resonance Imaging…

Computer Vision and Pattern Recognition · Computer Science 2019-02-13 Mustansar Fiaz , Kamran Ali , Abdul Rehman , M. Junaid Gul , Soon Ki Jung

Accurate brain lesion delineation is important for planning neurosurgical treatment. Automatic brain lesion segmentation methods based on convolutional neural networks have demonstrated remarkable performance. However, neural network…

Image and Video Processing · Electrical Eng. & Systems 2024-08-20 Jiayu Huo , Sebastien Ourselin , Rachel Sparks

Purpose: In this paper, we investigate a framework for interactive brain tumor segmentation which, at its core, treats the problem of interactive brain tumor segmentation as a machine learning problem. Methods: This method has an advantage…

Computer Vision and Pattern Recognition · Computer Science 2016-05-20 Mohammad Havaei , Hugo Larochelle , Philippe Poulin , Pierre-Marc Jodoin

Gliomas are the most common malignant brain tumors that are treated with chemoradiotherapy and surgery. Magnetic Resonance Imaging (MRI) is used by radiotherapists to manually segment brain lesions and to observe their development…

Image and Video Processing · Electrical Eng. & Systems 2020-11-30 Jonas Wacker , Marcelo Ladeira , José Eduardo Vaz Nascimento

Gliomas are the most common primary brain malignancies, with different degrees of aggressiveness, variable prognosis and various heterogeneous histologic sub-regions, i.e., peritumoral edematous/invaded tissue, necrotic core, active and…

Computer Vision and Pattern Recognition · Computer Science 2019-04-24 Spyridon Bakas , Mauricio Reyes , Andras Jakab , Stefan Bauer , Markus Rempfler , Alessandro Crimi , Russell Takeshi Shinohara , Christoph Berger , Sung Min Ha , Martin Rozycki , Marcel Prastawa , Esther Alberts , Jana Lipkova , John Freymann , Justin Kirby , Michel Bilello , Hassan Fathallah-Shaykh , Roland Wiest , Jan Kirschke , Benedikt Wiestler , Rivka Colen , Aikaterini Kotrotsou , Pamela Lamontagne , Daniel Marcus , Mikhail Milchenko , Arash Nazeri , Marc-Andre Weber , Abhishek Mahajan , Ujjwal Baid , Elizabeth Gerstner , Dongjin Kwon , Gagan Acharya , Manu Agarwal , Mahbubul Alam , Alberto Albiol , Antonio Albiol , Francisco J. Albiol , Varghese Alex , Nigel Allinson , Pedro H. A. Amorim , Abhijit Amrutkar , Ganesh Anand , Simon Andermatt , Tal Arbel , Pablo Arbelaez , Aaron Avery , Muneeza Azmat , Pranjal B. , W Bai , Subhashis Banerjee , Bill Barth , Thomas Batchelder , Kayhan Batmanghelich , Enzo Battistella , Andrew Beers , Mikhail Belyaev , Martin Bendszus , Eze Benson , Jose Bernal , Halandur Nagaraja Bharath , George Biros , Sotirios Bisdas , James Brown , Mariano Cabezas , Shilei Cao , Jorge M. Cardoso , Eric N Carver , Adrià Casamitjana , Laura Silvana Castillo , Marcel Catà , Philippe Cattin , Albert Cerigues , Vinicius S. Chagas , Siddhartha Chandra , Yi-Ju Chang , Shiyu Chang , Ken Chang , Joseph Chazalon , Shengcong Chen , Wei Chen , Jefferson W Chen , Zhaolin Chen , Kun Cheng , Ahana Roy Choudhury , Roger Chylla , Albert Clérigues , Steven Colleman , Ramiro German Rodriguez Colmeiro , Marc Combalia , Anthony Costa , Xiaomeng Cui , Zhenzhen Dai , Lutao Dai , Laura Alexandra Daza , Eric Deutsch , Changxing Ding , Chao Dong , Shidu Dong , Wojciech Dudzik , Zach Eaton-Rosen , Gary Egan , Guilherme Escudero , Théo Estienne , Richard Everson , Jonathan Fabrizio , Yong Fan , Longwei Fang , Xue Feng , Enzo Ferrante , Lucas Fidon , Martin Fischer , Andrew P. French , Naomi Fridman , Huan Fu , David Fuentes , Yaozong Gao , Evan Gates , David Gering , Amir Gholami , Willi Gierke , Ben Glocker , Mingming Gong , Sandra González-Villá , T. Grosges , Yuanfang Guan , Sheng Guo , Sudeep Gupta , Woo-Sup Han , Il Song Han , Konstantin Harmuth , Huiguang He , Aura Hernández-Sabaté , Evelyn Herrmann , Naveen Himthani , Winston Hsu , Cheyu Hsu , Xiaojun Hu , Xiaobin Hu , Yan Hu , Yifan Hu , Rui Hua , Teng-Yi Huang , Weilin Huang , Sabine Van Huffel , Quan Huo , Vivek HV , Khan M. Iftekharuddin , Fabian Isensee , Mobarakol Islam , Aaron S. Jackson , Sachin R. Jambawalikar , Andrew Jesson , Weijian Jian , Peter Jin , V Jeya Maria Jose , Alain Jungo , B Kainz , Konstantinos Kamnitsas , Po-Yu Kao , Ayush Karnawat , Thomas Kellermeier , Adel Kermi , Kurt Keutzer , Mohamed Tarek Khadir , Mahendra Khened , Philipp Kickingereder , Geena Kim , Nik King , Haley Knapp , Urspeter Knecht , Lisa Kohli , Deren Kong , Xiangmao Kong , Simon Koppers , Avinash Kori , Ganapathy Krishnamurthi , Egor Krivov , Piyush Kumar , Kaisar Kushibar , Dmitrii Lachinov , Tryphon Lambrou , Joon Lee , Chengen Lee , Yuehchou Lee , M Lee , Szidonia Lefkovits , Laszlo Lefkovits , James Levitt , Tengfei Li , Hongwei Li , Wenqi Li , Hongyang Li , Xiaochuan Li , Yuexiang Li , Heng Li , Zhenye Li , Xiaoyu Li , Zeju Li , XiaoGang Li , Wenqi Li , Zheng-Shen Lin , Fengming Lin , Pietro Lio , Chang Liu , Boqiang Liu , Xiang Liu , Mingyuan Liu , Ju Liu , Luyan Liu , Xavier Llado , Marc Moreno Lopez , Pablo Ribalta Lorenzo , Zhentai Lu , Lin Luo , Zhigang Luo , Jun Ma , Kai Ma , Thomas Mackie , Anant Madabushi , Issam Mahmoudi , Klaus H. Maier-Hein , Pradipta Maji , CP Mammen , Andreas Mang , B. S. Manjunath , Michal Marcinkiewicz , S McDonagh , Stephen McKenna , Richard McKinley , Miriam Mehl , Sachin Mehta , Raghav Mehta , Raphael Meier , Christoph Meinel , Dorit Merhof , Craig Meyer , Robert Miller , Sushmita Mitra , Aliasgar Moiyadi , David Molina-Garcia , Miguel A. B. Monteiro , Grzegorz Mrukwa , Andriy Myronenko , Jakub Nalepa , Thuyen Ngo , Dong Nie , Holly Ning , Chen Niu , Nicholas K Nuechterlein , Eric Oermann , Arlindo Oliveira , Diego D. C. Oliveira , Arnau Oliver , Alexander F. I. Osman , Yu-Nian Ou , Sebastien Ourselin , Nikos Paragios , Moo Sung Park , Brad Paschke , J. Gregory Pauloski , Kamlesh Pawar , Nick Pawlowski , Linmin Pei , Suting Peng , Silvio M. Pereira , Julian Perez-Beteta , Victor M. Perez-Garcia , Simon Pezold , Bao Pham , Ashish Phophalia , Gemma Piella , G. N. Pillai , Marie Piraud , Maxim Pisov , Anmol Popli , Michael P. Pound , Reza Pourreza , Prateek Prasanna , Vesna Prkovska , Tony P. Pridmore , Santi Puch , Élodie Puybareau , Buyue Qian , Xu Qiao , Martin Rajchl , Swapnil Rane , Michael Rebsamen , Hongliang Ren , Xuhua Ren , Karthik Revanuru , Mina Rezaei , Oliver Rippel , Luis Carlos Rivera , Charlotte Robert , Bruce Rosen , Daniel Rueckert , Mohammed Safwan , Mostafa Salem , Joaquim Salvi , Irina Sanchez , Irina Sánchez , Heitor M. Santos , Emmett Sartor , Dawid Schellingerhout , Klaudius Scheufele , Matthew R. Scott , Artur A. Scussel , Sara Sedlar , Juan Pablo Serrano-Rubio , N. Jon Shah , Nameetha Shah , Mazhar Shaikh , B. Uma Shankar , Zeina Shboul , Haipeng Shen , Dinggang Shen , Linlin Shen , Haocheng Shen , Varun Shenoy , Feng Shi , Hyung Eun Shin , Hai Shu , Diana Sima , M Sinclair , Orjan Smedby , James M. Snyder , Mohammadreza Soltaninejad , Guidong Song , Mehul Soni , Jean Stawiaski , Shashank Subramanian , Li Sun , Roger Sun , Jiawei Sun , Kay Sun , Yu Sun , Guoxia Sun , Shuang Sun , Yannick R Suter , Laszlo Szilagyi , Sanjay Talbar , Dacheng Tao , Dacheng Tao , Zhongzhao Teng , Siddhesh Thakur , Meenakshi H Thakur , Sameer Tharakan , Pallavi Tiwari , Guillaume Tochon , Tuan Tran , Yuhsiang M. Tsai , Kuan-Lun Tseng , Tran Anh Tuan , Vadim Turlapov , Nicholas Tustison , Maria Vakalopoulou , Sergi Valverde , Rami Vanguri , Evgeny Vasiliev , Jonathan Ventura , Luis Vera , Tom Vercauteren , C. A. Verrastro , Lasitha Vidyaratne , Veronica Vilaplana , Ajeet Vivekanandan , Guotai Wang , Qian Wang , Chiatse J. Wang , Weichung Wang , Duo Wang , Ruixuan Wang , Yuanyuan Wang , Chunliang Wang , Guotai Wang , Ning Wen , Xin Wen , Leon Weninger , Wolfgang Wick , Shaocheng Wu , Qiang Wu , Yihong Wu , Yong Xia , Yanwu Xu , Xiaowen Xu , Peiyuan Xu , Tsai-Ling Yang , Xiaoping Yang , Hao-Yu Yang , Junlin Yang , Haojin Yang , Guang Yang , Hongdou Yao , Xujiong Ye , Changchang Yin , Brett Young-Moxon , Jinhua Yu , Xiangyu Yue , Songtao Zhang , Angela Zhang , Kun Zhang , Xuejie Zhang , Lichi Zhang , Xiaoyue Zhang , Yazhuo Zhang , Lei Zhang , Jianguo Zhang , Xiang Zhang , Tianhao Zhang , Sicheng Zhao , Yu Zhao , Xiaomei Zhao , Liang Zhao , Yefeng Zheng , Liming Zhong , Chenhong Zhou , Xiaobing Zhou , Fan Zhou , Hongtu Zhu , Jin Zhu , Ying Zhuge , Weiwei Zong , Jayashree Kalpathy-Cramer , Keyvan Farahani , Christos Davatzikos , Koen van Leemput , Bjoern Menze

Magnetic resonance imaging (MRI) is a central modality for stroke imaging. It is used upon patient admission to make treatment decisions such as selecting patients for intravenous thrombolysis or endovascular therapy. MRI is later used in…

The medical imaging community generates a wealth of datasets, many of which are openly accessible and annotated for specific diseases and tasks such as multi-organ or lesion segmentation. Current practices continue to limit model training…

Image and Video Processing · Electrical Eng. & Systems 2024-01-09 Constantin Ulrich , Fabian Isensee , Tassilo Wald , Maximilian Zenk , Michael Baumgartner , Klaus H. Maier-Hein

Brains with complex distortion of cerebral anatomy present several challenges to automatic tissue segmentation methods of T1-weighted MR images. First, the very high variability in the morphology of the tissues can be incompatible with the…

Tissues and Organs · Quantitative Biology 2020-03-25 Gabriele Amorosino , Denis Peruzzo , Pietro Astolfi , Daniela Redaelli , Paolo Avesani , Filippo Arrigoni , Emanuele Olivetti

Brain pathologies can vary greatly in size and shape, ranging from few pixels (i.e. MS lesions) to large, space-occupying tumors. Recently proposed Autoencoder-based methods for unsupervised anomaly segmentation in brain MRI have shown…

Image and Video Processing · Electrical Eng. & Systems 2020-06-24 Christoph Baur , Benedikt Wiestler , Shadi Albarqouni , Nassir Navab