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The independence clustering problem is considered in the following formulation: given a set $S$ of random variables, it is required to find the finest partitioning $\{U_1,\dots,U_k\}$ of $S$ into clusters such that the clusters…

Machine Learning · Computer Science 2017-03-21 Daniil Ryabko

Randomized controlled trials (RCTs) often exhibit limited inferential efficiency in estimating treatment effects due to small sample sizes. In recent years, the combination of external controls has gained increasing attention as a means of…

Methodology · Statistics 2025-10-06 Qinwei Yang , Jingyi Li , Peng Wu

Determining conditional independence (CI) relationships between random variables is a fundamental yet challenging task in machine learning and statistics, especially in high-dimensional settings. Existing generative model-based CI testing…

Machine Learning · Computer Science 2025-05-30 Yixin Ren , Chenghou Jin , Yewei Xia , Li Ke , Longtao Huang , Hui Xue , Hao Zhang , Jihong Guan , Shuigeng Zhou

Causal phenomena associated with rare events occur across a wide range of engineering problems, such as risk-sensitive safety analysis, accident analysis and prevention, and extreme value theory. However, current methods for causal…

Machine Learning · Statistics 2023-07-19 Chih-Yuan Chiu , Kshitij Kulkarni , Shankar Sastry

We study the problem of multivariate regression where the data are naturally grouped, and a regression matrix is to be estimated for each group. We propose an approach in which a dictionary of low rank parameter matrices is estimated across…

Machine Learning · Computer Science 2012-07-03 Min Xu , John Lafferty

We study the data-driven selection of causal graphical models using constraint-based algorithms, which determine the existence or non-existence of edges (causal connections) in a graph based on testing a series of conditional independence…

Methodology · Statistics 2026-04-29 Daniel Malinsky

Multiple hypothesis testing (MHT) frequently arises in scientific inquiries, and concurrent testing of multiple hypotheses inflates the risk of Type-I errors or false positives, rendering MHT corrections essential. This paper addresses MHT…

Randomized controlled trials (RCTs) are the gold standard for evaluating causal effects but are often costly and difficult to scale; consequently, they are frequently augmented with auxiliary external controls in many applications. Prior…

Methodology · Statistics 2026-05-28 Jiawei Shan , Yiteng Tu , Guanbo Wang , Chao Ying , Jiwei Zhao

External controls from historical trials or observational data can augment randomized controlled trials when large-scale randomization is impractical or unethical, such as in drug evaluation for rare diseases. However, non-randomized…

Methodology · Statistics 2025-05-08 Ke Zhu , Shu Yang , Xiaofei Wang

Independence analysis is an indispensable step before regression analysis to find out essential factors that influence the objects. With many applications in machine Learning, medical Learning and a variety of disciplines, statistical…

Methodology · Statistics 2022-07-08 Wenliang Pan , Yujue Li , Jianwu Liu , Pei Dang , Weixiong Mai

We consider the problem of testing whether a correlation matrix of a multivariate normal population is the identity matrix. We focus on sparse classes of alternatives where only a few entries are nonzero and, in fact, positive. We derive a…

Statistics Theory · Mathematics 2015-04-15 Ery Arias-Castro , Sébastien Bubeck , Gábor Lugosi

We formulate and analyze a graphical model selection method for inferring the conditional independence graph of a high-dimensional nonstationary Gaussian random process (time series) from a finite-length observation. The observed process…

Machine Learning · Statistics 2016-09-14 Nguyen Tran Quang , Alexander Jung

Graphical causal models are an important tool for knowledge discovery because they can represent both the causal relations between variables and the multivariate probability distributions over the data. Once learned, causal graphs can be…

Artificial Intelligence · Computer Science 2017-04-11 Andrew J Sedgewick , Joseph D. Ramsey , Peter Spirtes , Clark Glymour , Panayiotis V. Benos

A central goal in experimental high energy physics is to detect new physics signals that are not explained by known physics. In this paper, we aim to search for new signals that appear as deviations from known Standard Model physics in…

Applications · Statistics 2022-12-14 Purvasha Chakravarti , Mikael Kuusela , Jing Lei , Larry Wasserman

There is growing interest in a hybrid control design for treatment evaluation, where a randomized controlled trial is augmented with external control data from a previous trial or a real world data source. The hybrid control design has the…

Methodology · Statistics 2026-05-06 Zhiwei Zhang , Peisong Han , Wei Zhang

This paper develops a method to obtain the optimal value for the regularization coefficient in a general mixed-integer problem (MIP). This approach eliminates the cross-validation performed in the existing penalty techniques to obtain a…

Optimization and Control · Mathematics 2020-08-05 Behrad Soleimani , Behzad Khamidehi , Maryam Sabbaghian

Large-scale testing in modern applications such as genomics often entails a trade-off between accuracy and speed: multiplicity corrections push cutoffs deep into the tails, where normal approximations can fail, while resampling is accurate…

Methodology · Statistics 2025-11-21 Ziang Niu , Jyotishka Ray Choudhury , Eugene Katsevich

Testing cross-sectional independence in panel data models is of fundamental importance in econometric analysis with high-dimensional panels. Recently, econometricians began to turn their attention to the problem in the presence of serial…

Methodology · Statistics 2023-09-18 Hongfei Wang , Binghui Liu , Long Feng , Yanyuan Ma

This article proposes a generalized notion of extreme multivariate dependence between two random vectors which relies on the extremality of the cross-covariance matrix between these two vectors. Using a partial ordering on the…

Econometrics · Economics 2021-02-10 Damien Bosc , Alfred Galichon

Computing observables from conditioned dynamics is typically computationally hard, because, although obtaining independent samples efficiently from the unconditioned dynamics is usually feasible, generally most of the samples must be…

Data Analysis, Statistics and Probability · Physics 2026-01-08 Alfredo Braunstein , Giovanni Catania , Luca Dall'Asta , Matteo Mariani , Anna Paola Muntoni
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