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Non-terminal events can represent a meaningful change in a patient's life. Thus, better understanding and predicting their occurrence can bring valuable information to individuals. In a context where longitudinal markers could inform these…

Methodology · Statistics 2025-01-16 Juliette Ortholand , Stanley Durrleman , Sophie Tezenas du Montcel

We present a stochastic epidemic model to study the effect of various preventive measures, such as uniform reduction of contacts and transmission, vaccination, isolation, screening and contact tracing, on a disease outbreak in a…

Populations and Evolution · Quantitative Biology 2022-07-08 Martina Favero , Gianpaolo Scalia Tomba , Tom Britton

The aerosol mixing state significantly affects the climate and health impacts of atmospheric aerosol particles. Simplified aerosol mixing state assumptions, common in Earth System models, can introduce errors in the prediction of these…

Machine Learning · Computer Science 2020-12-08 Zhonghua Zheng , Joseph Ching , Jeffrey H. Curtis , Yu Yao , Peng Xu , Matthew West , Nicole Riemer

Airway constriction and blockage in obstructive lung diseases cause ventilation heterogeneity and create barriers to effective drug deposition. Established computational particle-deposition models have not accounted for these impacts of…

Tissues and Organs · Quantitative Biology 2024-10-17 James D. Shemilt , Alex Horsley , Jim M. Wild , Oliver E. Jensen , Alice B. Thompson , Carl A. Whitfield

Air pollution is a worldwide public health threat that can cause or exacerbate many illnesses, including respiratory disease, cardiovascular disease, and some cancers. However, epidemiological studies and public health decision-making are…

Variability on external conditions has important consequences for the dynamics and the organization of biological systems. In many cases, the characteristic timescale of environmental changes as well as their correlations play a fundamental…

Populations and Evolution · Quantitative Biology 2017-10-03 Tommaso Spanio , Jorge Hidalgo , Miguel A. Muñoz

The impact of wildfire smoke on air quality is a growing concern, contributing to air pollution through a complex mixture of chemical species with important implications for public health. While previous studies have primarily focused on…

Methodology · Statistics 2026-02-10 Dafne Zorzetto , Jenna Landy , Corwin Zigler , Giovanni Parmigiani , Roberta De Vito

Ambient air pollution poses significant health and environmental challenges. Exposure to high concentrations of PM$_{2.5}$ have been linked to increased respiratory and cardiovascular hospital admissions, more emergency department visits…

Applications · Statistics 2026-02-27 Zeinab Mohamed , Wenlong Gong

This paper considers identification and estimation of distributional effect parameters that depend on the joint distribution of an outcome and another variable of interest ("treatment") in a setting with "two-sided" measurement error --…

Econometrics · Economics 2025-09-23 Brantly Callaway , Tong Li , Irina Murtazashvili , Emmanuel Tsyawo

In observational studies with survival or time-to-event outcomes, a propensity score weighted marginal Cox proportional hazard model with the treatment variable as the only predictor is commonly used to estimate the causal marginal hazard…

Methodology · Statistics 2026-02-02 Zixian Zhao , Chengxin Yang , Fan Li

Flexible estimation of multiple conditional quantiles is of interest in numerous applications, such as studying the effect of pregnancy-related factors on low and high birth weight. We propose a Bayesian non-parametric method to…

Methodology · Statistics 2021-10-22 Steven G. Xu , Brian J. Reich

Accurate and interpretable air pollution forecasting is crucial for public health, but most models face a trade-off between performance and interpretability. This study proposes a physics-guided, interpretable-by-design spatiotemporal…

Machine Learning · Computer Science 2026-01-23 Zhiguo Zhang , Xiaoliang Ma , Daniel Schlesinger

In environmental health research, it is of interest to understand the effect of the neighborhood environment on health. Researchers have shown a protective association between green space around a person's residential address and depression…

We develop a Gaussian-process mixture model for heterogeneous treatment effect estimation that leverages the use of transformed outcomes. The approach we will present attempts to improve point estimation and uncertainty quantification…

Methodology · Statistics 2018-12-19 Abbas Zaidi , Sayan Mukherjee

Pollutant emissions from coal-burning power plants have been deemed to adversely impact ambient air quality and public health conditions. Despite the noticeable reduction in emissions and the improvement of air quality since the Clean Air…

Methodology · Statistics 2019-01-07 Chanmin Kim , Corwin M Zigler , Michael J Daniels , Christine Choirat , Jason A Roy

Time-course gene expression datasets provide insight into the dynamics of complex biological processes, such as immune response and organ development. It is of interest to identify genes with similar temporal expression patterns because…

Estimating the causal effects of a spatially-varying intervention on a spatially-varying outcome may be subject to non-local confounding (NLC), a phenomenon that can bias estimates when the treatments and outcomes of a given unit are…

Machine Learning · Computer Science 2022-12-13 Mauricio Tec , James Scott , Corwin Zigler

Ambient concentrations of many pollutants are associated with emissions due to human activity, such as road transport and other combustion sources. In this paper we consider air pollution as a multi--level phenomenon within a Bayesian…

Applications · Statistics 2011-10-17 Gavin Shaddick , Haojie Yan , Danielle Vienneau

The objective is to model longitudinal and survival data jointly taking into account the dependence between the two responses in a real HIV/AIDS dataset using a shared parameter approach inside a Bayesian framework. We propose a linear…

Applications · Statistics 2016-05-02 Rui Martins

We present a statistical modelling framework for implementing Distributed Lag Models (DLMs), encompassing several extensions of the approach to capture the temporally distributed effect from covariates via regression. We place DLMs in the…