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Despite the growing interest in Explainable Artificial Intelligence (XAI), explainability is rarely considered during hyperparameter tuning or neural architecture optimization, where the focus remains primarily on minimizing predictive…

Machine Learning · Computer Science 2025-05-26 Alexander Hinterleitner , Thomas Bartz-Beielstein

Shape measures have emerged as promising descriptors of white matter tractography, offering complementary insights into anatomical variability and associations with cognitive and clinical phenotypes. However, conventional methods for…

Image and Video Processing · Electrical Eng. & Systems 2025-10-22 Yui Lo , Yuqian Chen , Dongnan Liu , Leo Zekelman , Jarrett Rushmore , Yogesh Rathi , Nikos Makris , Alexandra J. Golby , Fan Zhang , Weidong Cai , Lauren J. O'Donnell

Magnetic resonance imaging (MRI) is a central modality for stroke imaging. It is used upon patient admission to make treatment decisions such as selecting patients for intravenous thrombolysis or endovascular therapy. MRI is later used in…

This study addresses the challenge of stroke diagnosis and treatment under uncertainty, a critical issue given the rapid progression and severe consequences of stroke conditions such as aneurysms, arteriovenous malformations (AVM), and…

Artificial Intelligence · Computer Science 2024-07-25 Nur Ahmad Khatim , Ahmad Azmul Asmar Irfan , Amaliya Mata'ul Hayah , Mansur M. Arief

There have been several research works proposing new Explainable AI (XAI) methods designed to generate model explanations having specific properties, or desiderata, such as fidelity, robustness, or human-interpretability. However,…

Artificial Intelligence · Computer Science 2021-01-25 Sérgio Jesus , Catarina Belém , Vladimir Balayan , João Bento , Pedro Saleiro , Pedro Bizarro , João Gama

This article addresses the challenge of modeling the amplitude of spatially indexed low frequency fluctuations (ALFF) in resting state functional MRI as a function of cortical structural features and a multi-task coactivation network in the…

Methodology · Statistics 2026-02-09 Yeseul Jeon , Rajarshi Guhaniyogi , Aaron Scheffler

Traumatic brain injury (TBI) presents a significant public health challenge, often resulting in mortality or lasting disability. Predicting outcomes such as mortality and Functional Status Scale (FSS) scores can enhance treatment strategies…

Machine Learning · Computer Science 2024-10-29 Lucas Steinmetz , Shivam Maheshwari , Garik Kazanjian , Abigail Loyson , Tyler Alexander , Venkat Margapuri , C. Nataraj

Deep learning has been successful in predicting neurodegenerative disorders, such as Alzheimer's disease, from magnetic resonance imaging (MRI). Combining multiple imaging modalities, such as T1-weighted (T1) and diffusion-weighted imaging…

Artificial Intelligence · Computer Science 2026-01-30 Abhijith Shaji , Tamoghna Chattopadhyay , Sophia I. Thomopoulos , Greg Ver Steeg , Paul M. Thompson , Jose-Luis Ambite

Early identification of stroke is crucial for intervention, requiring reliable models. We proposed an efficient retinal image representation together with clinical information to capture a comprehensive overview of cardiovascular health,…

Computer Vision and Pattern Recognition · Computer Science 2024-11-11 Yuqing Huang , Bastian Wittmann , Olga Demler , Bjoern Menze , Neda Davoudi

Focal deficits in ischaemic stroke result from impaired perfusion downstream of a critical vascular occlusion. While parenchymal lesions are traditionally used to predict clinical deficits, the underlying pattern of disrupted perfusion…

While deep learning models have demonstrated remarkable success in numerous domains, their black-box nature remains a significant limitation, especially in critical fields such as medical image analysis and inference. Existing…

Machine Learning · Computer Science 2025-05-13 David Zucker

Large language models (LLMs) often achieve impressive predictive accuracy, yet correctness alone does not imply genuine understanding. True LLM understanding, analogous to human expertise, requires making consistent, well-founded decisions…

Computation and Language · Computer Science 2025-11-17 Sichao Li , Xinyue Xu , Xiaomeng Li

Decoding EEG during motor imagery is pivotal for the Brain-Computer Interface (BCI) system, influencing its overall performance significantly. As end-to-end data-driven learning methods advance, the challenge lies in balancing model…

Human-Computer Interaction · Computer Science 2025-01-28 Param Rajpura , Yogesh Kumar Meena

The evaluation and treatment of acute cerebral ischemia requires a technique that can determine the total area of tissue at risk for infarction using diagnostic magnetic resonance imaging (MRI) sequences. Typical MRI data sets consist of…

Computer Vision and Pattern Recognition · Computer Science 2016-06-14 Vishwa S. Parekh , Jeremy R. Jacobs , Michael A. Jacobs

This research aims develop an Explainable Artificial Intelligence (XAI) framework to facilitate human-understandable solutions for tool wear prediction during turning. A random forest algorithm was used as the supervised Machine Learning…

Machine Learning · Computer Science 2023-08-21 Saleh Valizadeh Sotubadi , Rui Liu , Vinh Neguyen

When applying a Deep Learning model to medical images, it is crucial to estimate the model uncertainty. Voxel-wise uncertainty is a useful visual marker for human experts and could be used to improve the model's voxel-wise output, such as…

Image and Video Processing · Electrical Eng. & Systems 2022-11-02 Anton Vasiliuk , Daria Frolova , Mikhail Belyaev , Boris Shirokikh

Many visualizations have been developed for explainable AI (XAI), but they often require further reasoning by users to interpret. Investigating XAI for high-stakes medical diagnosis, we propose improving domain alignment with diagrammatic…

Artificial Intelligence · Computer Science 2025-02-27 Brian Y. Lim , Joseph P. Cahaly , Chester Y. F. Sng , Adam Chew

Deep learning based disease detection and segmentation algorithms promise to improve many clinical processes. However, such algorithms require vast amounts of annotated training data, which are typically not available in the medical context…

Image and Video Processing · Electrical Eng. & Systems 2021-11-02 Moritz Platscher , Jonathan Zopes , Christian Federau

Convolutional Neural Networks (CNNs) are frequently and successfully used in medical prediction tasks. They are often used in combination with transfer learning, leading to improved performance when training data for the task are scarce.…

Computer Vision and Pattern Recognition · Computer Science 2026-01-22 Marta Oliveira , Rick Wilming , Benedict Clark , Céline Budding , Fabian Eitel , Kerstin Ritter , Stefan Haufe

In recent years, deep neural networks have showcased their predictive power across a variety of tasks. Beyond natural language processing, the transformer architecture has proven efficient in addressing tabular data problems and challenges…

Machine Learning · Computer Science 2025-04-14 Anton Thielmann , Arik Reuter , Benjamin Saefken
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