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Universal lesion detection and tagging (ULDT) in CT studies is critical for tumor burden assessment and tracking the progression of lesion status (growth/shrinkage) over time. However, a lack of fully annotated data hinders the development…

Computer Vision and Pattern Recognition · Computer Science 2025-04-08 Alexander Shieh , Tejas Sudharshan Mathai , Jianfei Liu , Angshuman Paul , Ronald M. Summers

Radiologists routinely perform the tedious task of lesion localization, classification, and size measurement in computed tomography (CT) studies. Universal lesion detection and tagging (ULDT) can simultaneously help alleviate the cumbersome…

Computer Vision and Pattern Recognition · Computer Science 2025-04-08 Jared Frazier , Tejas Sudharshan Mathai , Jianfei Liu , Angshuman Paul , Ronald M. Summers

Large-scale datasets with high-quality labels are desired for training accurate deep learning models. However, due to the annotation cost, datasets in medical imaging are often either partially-labeled or small. For example, DeepLesion is…

Computer Vision and Pattern Recognition · Computer Science 2021-01-05 Ke Yan , Jinzheng Cai , Youjing Zheng , Adam P. Harrison , Dakai Jin , Youbao Tang , Yuxing Tang , Lingyun Huang , Jing Xiao , Le Lu

Lesion detection is an important problem within medical imaging analysis. Most previous work focuses on detecting and segmenting a specialized category of lesions (e.g., lung nodules). However, in clinical practice, radiologists are…

Computer Vision and Pattern Recognition · Computer Science 2020-05-29 Ke Yan , Jinzheng Cai , Adam P. Harrison , Dakai Jin , Jing Xiao , Le Lu

In radiologists' routine work, one major task is to read a medical image, e.g., a CT scan, find significant lesions, and describe them in the radiology report. In this paper, we study the lesion description or annotation problem. Given a…

Computer Vision and Pattern Recognition · Computer Science 2019-04-30 Ke Yan , Yifan Peng , Veit Sandfort , Mohammadhadi Bagheri , Zhiyong Lu , Ronald M. Summers

Automatic segmentation of lesions in FDG-18 Whole Body (WB) PET/CT scans using deep learning models is instrumental for determining treatment response, optimizing dosimetry, and advancing theranostic applications in oncology. However, the…

Image and Video Processing · Electrical Eng. & Systems 2023-11-06 Gowtham Krishnan Murugesan , Diana McCrumb , Eric Brunner , Jithendra Kumar , Rahul Soni , Vasily Grigorash , Stephen Moore , Jeff Van Oss

Target imbalance affects the performance of recent deep learning methods in many medical image segmentation tasks. It is a twofold problem: class imbalance - positive class (lesion) size compared to negative class (non-lesion) size; lesion…

Image and Video Processing · Electrical Eng. & Systems 2020-07-21 Boris Shirokikh , Alexey Shevtsov , Anvar Kurmukov , Alexandra Dalechina , Egor Krivov , Valery Kostjuchenko , Andrey Golanov , Mikhail Belyaev

In this paper, we describe our method for the ISIC 2019 Skin Lesion Classification Challenge. The challenge comes with two tasks. For task 1, skin lesions have to be classified based on dermoscopic images. For task 2, dermoscopic images and…

Computer Vision and Pattern Recognition · Computer Science 2019-10-10 Nils Gessert , Maximilian Nielsen , Mohsin Shaikh , René Werner , Alexander Schlaefer

In clinical practice, radiologists are reliant on the lesion size when distinguishing metastatic from non-metastatic lesions. A prerequisite for lesion sizing is their detection, as it promotes the downstream assessment of tumor spread.…

Image and Video Processing · Electrical Eng. & Systems 2021-11-12 Tarun Mattikalli , Tejas Sudharshan Mathai , Ronald M. Summers

In radiologists' routine work, one major task is to read a medical image, e.g., a CT scan, find significant lesions, and write sentences in the radiology report to describe them. In this paper, we study the lesion description or annotation…

Computer Vision and Pattern Recognition · Computer Science 2019-03-28 Ke Yan , Yifan Peng , Zhiyong Lu , Ronald M. Summers

Deep convolutional neural network (DCNN) models have been widely explored for skin disease diagnosis and some of them have achieved the diagnostic outcomes comparable or even superior to those of dermatologists. However, broad…

Computer Vision and Pattern Recognition · Computer Science 2022-02-14 Peng Yao , Shuwei Shen , Mengjuan Xu , Peng Liu , Fan Zhang , Jinyu Xing , Pengfei Shao , Benjamin Kaffenberger , Ronald X. Xu

Accurate, automated lesion detection in Computed Tomography (CT) is an important yet challenging task due to the large variation of lesion types, sizes, locations and appearances. Recent work on CT lesion detection employs two-stage region…

Image and Video Processing · Electrical Eng. & Systems 2019-06-07 Martin Zlocha , Qi Dou , Ben Glocker

Fully annotated large-scale medical image datasets are highly valuable. However, because labeling medical images is tedious and requires specialized knowledge, the large-scale datasets available often have missing annotation issues. For…

Computer Vision and Pattern Recognition · Computer Science 2023-03-28 Xiaoyu Bai , Yong Xia

Automatic skin lesion classification from dermoscopy images is important for the early diagnosis of skin diseases such as melanoma. Class imbalance in skin lesion datasets, notably the defects in the representation of malignant(cancerous)…

Quantitative Methods · Quantitative Biology 2025-12-19 Ariful Islam Khandaker , Abdullah Al Shafi , Mohiuddin Ahmad

Skin lesions are an increasingly significant medical concern, varying widely in severity from benign to cancerous. Accurate diagnosis is essential for ensuring timely and appropriate treatment. This study examines the implementation of deep…

Computer Vision and Pattern Recognition · Computer Science 2024-09-09 Xiaoyi Liu , Zhou Yu , Lianghao Tan , Yafeng Yan , Ge Shi

Extracting, harvesting and building large-scale annotated radiological image datasets is a greatly important yet challenging problem. It is also the bottleneck to designing more effective data-hungry computing paradigms (e.g., deep…

Computer Vision and Pattern Recognition · Computer Science 2017-10-11 Ke Yan , Xiaosong Wang , Le Lu , Ronald M. Summers

Precise breast cancer classification on histopathological images has the potential to greatly improve the diagnosis and patient outcome in oncology. The data imbalance problem largely stems from the inherent imbalance within medical image…

Image and Video Processing · Electrical Eng. & Systems 2024-11-28 Majid Behzadpour , Bengie L. Ortiz , Ebrahim Azizi , Kai Wu

We propose a novel convolutional neural network for lesion detection from weak labels. Only a single, global label per image - the lesion count - is needed for training. We train a regression network with a fully convolutional architecture…

Computer Vision and Pattern Recognition · Computer Science 2017-10-31 Florian Dubost , Gerda Bortsova , Hieab Adams , Arfan Ikram , Wiro Niessen , Meike Vernooij , Marleen De Bruijne

The skin, as the largest organ of the human body, is vulnerable to a diverse array of conditions collectively known as skin lesions, which encompass various dermatoses. Diagnosing these lesions presents significant challenges for medical…

Image and Video Processing · Electrical Eng. & Systems 2025-01-13 Sauda Adiv Hanum , Ashim Dey , Muhammad Ashad Kabir

Automated analysis of tissue sections allows a better understanding of disease biology and may reveal biomarkers that could guide prognosis or treatment selection. In digital pathology, less abundant cell types can be of biological…

Image and Video Processing · Electrical Eng. & Systems 2021-02-24 Yeman Brhane Hagos , Catherine SY Lecat , Dominic Patel , Lydia Lee , Thien-An Tran , Manuel Rodriguez- Justo , Kwee Yong , Yinyin Yuan
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