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Related papers: $Q_B$-Optimal Two-Level Designs

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Background: Well-designed phase II trials must have acceptable error rates relative to a pre-specified success criterion, usually a statistically significant p-value. Such standard designs may not always suffice from a clinical perspective…

Applications · Statistics 2020-02-10 Satrajit Roychoudhury , Nicolas Scheuer , Beat Neuenschwander

Bilevel optimization is a popular two-level hierarchical optimization, which has been widely applied to many machine learning tasks such as hyperparameter learning, meta learning and continual learning. Although many bilevel optimization…

Optimization and Control · Mathematics 2023-11-21 Feihu Huang

Systems with both quantitative and qualitative responses are widely encountered in many applications. Design of experiment methods are needed when experiments are conducted to study such systems. Classic experimental design methods are…

Methodology · Statistics 2023-04-24 Lulu Kang , Xinwei Deng , Ran Jin

There have been some major advances in the theory of optimal designs for interference models. However, the majority of them focus on one-dimensional layout of the block and the study for two-dimensional interference model is quite limited…

Methodology · Statistics 2017-05-24 A. S. Hedayat , Heng Xu , Wei Zheng

Sequential trial design is an important statistical approach to increase the efficiency of clinical trials. Bayesian sequential trial design relies primarily on conducting a Monte Carlo simulation under the hypotheses of interest and…

Methodology · Statistics 2025-12-01 Riko Kelter , Samuel Pawel

Bilevel optimization is a key framework in hierarchical decision-making, where one problem is embedded within the constraints of another. In this work, we propose a control-theoretic approach to solving bilevel optimization problems. Our…

Optimization and Control · Mathematics 2025-03-25 Sina Sharifi , Nazanin Abolfazli , Erfan Yazdandoost Hamedani , Mahyar Fazlyab

Clinical decision-making often involves selecting tests that are costly, invasive, or time-consuming, motivating individualized, sequential strategies for what to measure and when to stop ascertaining. We study the problem of learning…

Machine Learning · Statistics 2026-04-16 Doudou Zhou , Yiran Zhang , Dian Jin , Yingye Zheng , Lu Tian , Tianxi Cai

Bilevel optimization is a hierarchical framework where an upper-level optimization problem is constrained by a lower-level problem, commonly used in machine learning applications such as hyperparameter optimization. Existing bilevel…

Optimization and Control · Mathematics 2026-03-03 Yuman Wu , Xiaochuan Gong , Jie Hao , Mingrui Liu

The study of good nonregular fractional factorial designs has received significant attention over the last two decades. Recent research indicates that designs constructed from quaternary codes (QC) are very promising in this regard. The…

Statistics Theory · Mathematics 2011-05-16 Runchu Zhang , Frederick K. H. Phoa , Rahul Mukerjee , Hongquan Xu

The analysis of low dimensional factorial designs with possible interactions is a relevant issue. Instead of the common pre-tests for interaction, a simultaneous inference procedure of the primary factor at the respective level of the…

Methodology · Statistics 2022-04-19 Ludwig A. Hothorn

Multilevel modeling and simulation (M&S) is becoming increasingly relevant due to the benefits that this methodology offers. Multilevel models allow users to describe a system at multiple levels of detail. From one side, this can make…

Software Engineering · Computer Science 2024-03-26 Luca Serena , Moreno Marzolla , Gabriele D'Angelo , Stefano Ferretti

Results from a triple-blind mixed-method user study into the effectiveness of mixed-initiative tools for the procedural generation of game levels are presented. A tool which generates levels using interactive evolutionary optimisation was…

Neural and Evolutionary Computing · Computer Science 2021-06-03 Sean P. Walton , Alma A. M. Rahat , James Stovold

Orthogonal Arrays allow us to test various levels of each factor and balance the different factors so that we can estimate interactions as well as first order effects. There is a trade-off between how well we can sample different levels of…

Methodology · Statistics 2016-01-26 Joel Atkins , David B. Zax

Tie-breaker designs trade off a statistical design objective with short-term gain from preferentially assigning a binary treatment to those with high values of a running variable $x$. The design objective is any continuous function of the…

Methodology · Statistics 2022-10-20 Harrison H. Li , Art B. Owen

A wide range of decision problems can be formulated as bilevel programs with independent followers, which as a special case include two-stage stochastic programs. These problems are notoriously difficult to solve especially when a large…

Optimization and Control · Mathematics 2025-09-25 Timothy C. Y. Chan , Bo Lin , Shoshanna Saxe

Factorial designs are often used in various industrial and sociological experiments to identify significant factors and factor combinations that may affect the process response. In the statistics literature, several studies have…

Methodology · Statistics 2020-12-16 Pratishtha Batra , Neil A. Spencer , Pritam Ranjan

It is shown how by not losing information on higher order interactions, optimal paired comparison designs involving alternatives of either full or partial profiles to reduce information overload as frequently encountered in applications can…

Methodology · Statistics 2019-12-04 Eric Nyarko

Bilevel programming is one of the very active areas of research with many real-life applications in economics and engineering. Bilevel problems are hierarchical problems consisting of lower-level and upper-level problems, respectively. The…

Optimization and Control · Mathematics 2025-10-24 Kuntal Som , Thirumulanathan D , Joydeep Dutta

The goal of this work is to fill a gap in [Yang, SIAM J. Matrix Anal. Appl, 41 (2020), 1797--1825]. In that work, an approximation procedure was proposed for orthogonal low-rank tensor approximation; however, the approximation lower bound…

Optimization and Control · Mathematics 2021-01-01 Yuning Yang

Bilevel optimization has become a powerful framework in various machine learning applications including meta-learning, hyperparameter optimization, and network architecture search. There are generally two classes of bilevel optimization…

Machine Learning · Computer Science 2021-08-03 Kaiyi Ji
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