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Clinical dataset labels are rarely certain as annotators disagree and confidence is not uniform across cases. Typical aggregation procedures, such as majority voting, obscure this variability. In simple experiments on medical imaging…

Propensity scores are often used for stratification of treatment and control groups of subjects in observational data to remove confounding bias when estimating of causal effect of the treatment on an outcome in so-called potential outcome…

Statistics Theory · Mathematics 2018-04-24 Priyantha Wijayatunga

We show that the Brier game of prediction is mixable and find the optimal learning rate and substitution function for it. The resulting prediction algorithm is applied to predict results of football and tennis matches. The theoretical…

Machine Learning · Computer Science 2009-11-02 Vladimir Vovk , Fedor Zhdanov

The bias of an estimator is defined as the difference of its expected value from the parameter to be estimated, where the expectation is with respect to the model. Loosely speaking, small bias reflects the desire that if an experiment is…

Methodology · Statistics 2018-02-16 Ioannis Kosmidis

Diagnostic tests play a crucial role in medical care. Thus any new diagnostic tests must undergo a thorough evaluation. New diagnostic tests are evaluated in comparison with the respective gold standard tests. The performance of binary…

Applications · Statistics 2025-09-17 Wan Nor Arifin , Umi Kalsom Yusof

The traditional binary classification framework constructs classifiers which may have good accuracy, but whose false positive and false negative error rates are not under users' control. In many cases, one of the errors is more severe and…

Machine Learning · Statistics 2020-10-22 Miloš Simić

In a recurrent events setting, we introduce a new score designed to evaluate the prediction ability, for a given model, of the expected cumulative number of recurrent events. This score allows to take into account the individual history of…

Methodology · Statistics 2023-02-03 Olivier Bouaziz

Classification systems are evaluated in a countless number of papers. However, we find that evaluation practice is often nebulous. Frequently, metrics are selected without arguments, and blurry terminology invites misconceptions. For…

Machine Learning · Computer Science 2024-07-03 Juri Opitz

Probability estimation models play an important role in various fields, such as weather forecasting, recommendation systems, and sports analysis. Among several models estimating probabilities, it is difficult to evaluate which model gives…

Machine Learning · Computer Science 2024-06-06 Euihyeon Choi , Jooyoung Kim , Wonkyung Lee

Medical researchers have solved the problem of estimating the sensitivity and specificity of binary medical diagnostic tests without gold standard tests for comparison. That problem is the same as estimating confusion matrices for…

Machine Learning · Statistics 2022-12-29 Richard Evans

Machine learning is increasingly being used to generate prediction models for use in a number of real-world settings, from credit risk assessment to clinical decision support. Recent discussions have highlighted potential problems in the…

This is a report about the use and misuse of citation data in the assessment of scientific research. The idea that research assessment must be done using ``simple and objective'' methods is increasingly prevalent today. The ``simple and…

Methodology · Statistics 2009-10-20 Robert Adler , John Ewing , Peter Taylor

Outcomes of data-driven AI models cannot be assumed to be always correct. To estimate the uncertainty in these outcomes, the uncertainty wrapper framework has been proposed, which considers uncertainties related to model fit, input quality,…

Machine Learning · Computer Science 2022-01-11 Pascal Gerber , Lisa Jöckel , Michael Kläs

In biomedical and public health association studies, binary outcome variables may be subject to misclassification, resulting in substantial bias in effect estimates. The feasibility of addressing binary outcome misclassification in…

Methodology · Statistics 2024-03-19 Kimberly A. Hochstedler Webb , Martin T. Wells

Binary classification models which can assign probabilities to categories such as "the tissue is 75% likely to be tumorous" or "the chemical is 25% likely to be toxic" are well understood statistically, but their utility as an input to…

Applications · Statistics 2017-12-05 Damjan Krstajic , Ljubomir Buturovic , Simon Thomas , David E Leahy

Calibration is a frequently invoked concept when useful label probability estimates are required on top of classification accuracy. A calibrated model is a function whose values correctly reflect underlying label probabilities. Calibration…

Machine Learning · Computer Science 2024-12-03 Alireza Torabian , Ruth Urner

Although propensity scores have been central to the estimation of causal effects for over 30 years, only recently has the statistical literature begun to consider in detail methods for Bayesian estimation of propensity scores and causal…

Methodology · Statistics 2014-04-09 Corwin M. Zigler

Binary observations are often repeated to improve data quality, creating technical replicates. Several scoring methods are commonly used to infer the actual individual state and obtain a probability for each state. The common practice of…

Methodology · Statistics 2025-01-24 Manuela Royer-Carenzi , Hadrien Lorenzo , Pierre Pudlo

Mediation analyses allow researchers to quantify the effect of an exposure variable on an outcome variable through a mediator variable. If a binary mediator variable is misclassified, the resulting analysis can be severely biased.…

Methodology · Statistics 2024-07-19 Kimberly A. Hochstedler Webb , Martin T. Wells

The propensity score is a common tool for estimating the causal effect of a binary treatment in observational data. In this setting, matching, subclassification, imputation, or inverse probability weighting on the propensity score can…

Methodology · Statistics 2018-01-03 Michael J Lopez , Roee Gutman