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While machine learning is currently transforming the field of histopathology, the domain lacks a comprehensive evaluation of state-of-the-art models based on essential but complementary quality requirements beyond a mere classification…

Image and Video Processing · Electrical Eng. & Systems 2023-05-11 Maximilian Springenberg , Annika Frommholz , Markus Wenzel , Eva Weicken , Jackie Ma , Nils Strodthoff

Histopathology image classification is crucial for the accurate identification and diagnosis of various diseases but requires large and diverse datasets. Obtaining such datasets, however, is often costly and time-consuming due to the need…

Computer Vision and Pattern Recognition · Computer Science 2024-09-25 Leire Benito-Del-Valle , Aitor Alvarez-Gila , Itziar Eguskiza , Cristina L. Saratxaga

Convolution Neural Networks (CNNs) are widely used in medical image analysis, but their performance degrade when the magnification of testing images differ from the training images. The inability of CNNs to generalize across magnification…

Image and Video Processing · Electrical Eng. & Systems 2023-02-23 Pranav Jeevan , Nikhil Cherian Kurian , Amit Sethi

Advance in medical imaging is an important part in deep learning research. One of the goals of computer vision is development of a holistic, comprehensive model which can identify tumors from histology slides obtained via biopsies. A major…

Image and Video Processing · Electrical Eng. & Systems 2024-12-18 Vidit Gautam

Computer-aided diagnosis (CAD) based on histopathological imaging has progressed rapidly in recent years with the rise of machine learning based methodologies. Traditional approaches consist of training a classification model using features…

Computer Vision and Pattern Recognition · Computer Science 2019-03-29 Junaid Malik , Serkan Kiranyaz , Suchitra Kunhoth , Turker Ince , Somaya Al-Maadeed , Ridha Hamila , Moncef Gabbouj

Medical image classification is one of the most critical problems in the image recognition area. One of the major challenges in this field is the scarcity of labelled training data. Additionally, there is often class imbalance in datasets…

Image and Video Processing · Electrical Eng. & Systems 2022-09-29 Khushboo Mehra , Hassan Soliman , Soumya Ranjan Sahoo

Visual microscopic study of diseased tissue by pathologists has been the cornerstone for cancer diagnosis and prognostication for more than a century. Recently, deep learning methods have made significant advances in the analysis and…

Image and Video Processing · Electrical Eng. & Systems 2022-09-30 Puria Azadi Moghadam , Sanne Van Dalen , Karina C. Martin , Jochen Lennerz , Stephen Yip , Hossein Farahani , Ali Bashashati

Colon cancer also known as Colorectal cancer, is one of the most malignant types of cancer worldwide. Early-stage detection of colon cancer is highly crucial to prevent its deterioration. This research presents a hybrid multi-scale deep…

Computer Vision and Pattern Recognition · Computer Science 2025-09-04 Sadra Saremi , Amirhossein Ahmadkhan Kordbacheh

Collaborative machine learning across healthcare institutions promises improved diagnostic accuracy by leveraging diverse datasets, yet privacy regulations such as HIPAA prohibit direct patient data sharing. While federated learning (FL)…

Computer Vision and Pattern Recognition · Computer Science 2025-11-27 Al Amin , Kamrul Hasan , Liang Hong , Sharif Ullah

Colorectal cancer (CRC) grading is a critical prognostic factor but remains hampered by inter-observer variability and the privacy constraints of multi-institutional data sharing. While deep learning offers a path to automation, centralized…

An optical microscopic examination of thinly cut stained tissue on glass slides prepared from a FFPE tissue blocks is the gold standard for tissue diagnostics. In addition, the diagnostic abilities and expertise of any pathologist is…

Deep learning models for semantic segmentation of images require large amounts of data. In the medical imaging domain, acquiring sufficient data is a significant challenge. Labeling medical image data requires expert knowledge.…

Machine Learning · Computer Science 2018-10-24 Micah J Sheller , G Anthony Reina , Brandon Edwards , Jason Martin , Spyridon Bakas

Deep learning for cancer histopathology training conflicts with privacy constraints in clinical settings. Federated Learning (FL) mitigates this by keeping data local; however, its performance depends on hyperparameter choices under…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Elisa Gonçalves Ribeiro , Rodrigo Moreira , Larissa Ferreira Rodrigues Moreira , André Ricardo Backes

Labelling data is expensive and time consuming especially for domains such as medical imaging that contain volumetric imaging data and require expert knowledge. Exploiting a larger pool of labeled data available across multiple centers,…

Computer Vision and Pattern Recognition · Computer Science 2020-09-03 Daiqing Li , Amlan Kar , Nishant Ravikumar , Alejandro F Frangi , Sanja Fidler

Deep Learning-based computational pathology algorithms have demonstrated profound ability to excel in a wide array of tasks that range from characterization of well known morphological phenotypes to predicting non-human-identifiable…

Image and Video Processing · Electrical Eng. & Systems 2020-09-24 Ming Y. Lu , Dehan Kong , Jana Lipkova , Richard J. Chen , Rajendra Singh , Drew F. K. Williamson , Tiffany Y. Chen , Faisal Mahmood

Accurate and scalable cancer diagnosis remains a critical challenge in modern pathology, particularly for malignancies such as breast, prostate, bone, and cervical, which exhibit complex histological variability. In this study, we propose a…

Image and Video Processing · Electrical Eng. & Systems 2025-08-18 Faisal Ahmed

Histopathology can help clinicians make accurate diagnoses, determine disease prognosis, and plan appropriate treatment strategies. As deep learning techniques prove successful in the medical domain, the primary challenges become limited…

Computer Vision and Pattern Recognition · Computer Science 2024-07-11 Zhe Li , Bernhard Kainz

The segmentation of medical images is important for the improvement and creation of healthcare systems, particularly for early disease detection and treatment planning. In recent years, the use of convolutional neural networks (CNNs) and…

Image and Video Processing · Electrical Eng. & Systems 2024-01-12 Siddharth Tiwari

We explore the problem of classification within a medical image data-set based on a feature vector extracted from the deepest layer of pre-trained Convolution Neural Networks. We have used feature vectors from several pre-trained…

Computer Vision and Pattern Recognition · Computer Science 2017-10-17 Brady Kieffer , Morteza Babaie , Shivam Kalra , H. R. Tizhoosh

Histology imaging is an essential diagnosis method to finalize the grade and stage of cancer of different tissues, especially for breast cancer diagnosis. Specialists often disagree on the final diagnosis on biopsy tissue due to the complex…

Computer Vision and Pattern Recognition · Computer Science 2019-09-17 Yongxiang Huang , Albert Chi-shing Chung
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