Related papers: A novel methodology to estimate pileup effects and…
Microdosimetry investigates the energy deposition of ionizing radiation at microscopic scales, beyond the assessment capabilities of macroscopic dosimetry. This contributes to an understanding of the biological response in radiobiology,…
Compared with the start-of-art energy integration detectors (EIDs), photon-counting detectors (PCDs) with energy discrimination capabilities have demonstrated great potentials in various applications of medical x-ray radiography and…
A Geant4-based Monte Carlo model for Heavy-Ion Therapy (MCHIT) is used to study radiation fields of H-1, He-4, Li-7 and C-12 beams with similar ranges (~160-180 mm) in water. Microdosimetry spectra are simulated for wall-less and walled…
The hard-scatter processes in hadronic collisions are often largely contaminated with soft background coming from pileup in proton-proton collisions, or underlying event in heavy-ion collisions. There are multiple methods to remove the…
The large rate of multiple simultaneous proton--proton interactions, or pile-up, generated by the Large Hadron Collider in Run 1 required the development of many new techniques to mitigate the adverse effects of these conditions. This paper…
Proton minibeam (pMB) radiotherapy, delivers highly heterogeneous dose distributions alternating high-dose peaks and low-dose valleys. This aims to widen the therapeutic window by improving normal tissue sparing while maintaining the same…
We consider a density estimation problem arising in nuclear physics. Gamma photons are impinging on a semiconductor detector, producing pulses of current. The integral of this pulse is equal to the total amount of charge created by the…
The tethered-particle method is a single-molecule technique that has been used to explore the dynamics of a variety of macromolecules of biological interest. We give a theoretical analysis of the particle motions in such experiments. Our…
Pulse-pileup affects most photon counting systems and occurs when photon detections occur faster than the detector's registration and recovery time. At high input rates, shaped pulses interfere and the source spectrum, as well as intensity…
Detector characterization and instrumentation testing are often performed at cyclotron and synchrotron facilities, many of which were originally developed for medical applications in cancer therapy. For particle physics experiments…
Microscopy research often requires recovering particle-size distributions in three dimensions from only a few (10 - 200) profile measurements in the section. This problem is especially relevant for petrographic and mineralogical studies,…
The highly energetic electrons in a transmission electron microscope (TEM) can alter or even completely destroy the structure of samples before sufficient information can be obtained. This is especially problematic in the case of zeolites,…
Measurements of the proton's form factor ratio made with polarization transfer show a striking discrepancy relative to the ratio extracted from unpolarized elastic electron-proton scattering cross sections. One hypothesis is that the…
Accurate phase estimation at the edge of data segments is crucial for EEG applications such as EEG-TMS in offline and real-time data analysis. Our research evaluates the phase estimation performance of four commonly used methods…
We propose a new method for pileup mitigation by implementing "pileup per particle identification" (PUPPI). For each particle we first define a local shape $\alpha$ which probes the collinear versus soft diffuse structure in the…
We study randomized experiments in bipartite systems where only a subset of treatment-side units are eligible for assignment while all units continue to interact, generating interference. We formalize eligibility-constrained bipartite…
When calculating satellite trajectories in low-earth orbit, engineers need to adequately estimate aerodynamic forces. But to this day, obtaining the drag acting on the complicated shapes of modern spacecraft suffers from many sources of…
Measurements of the ratio of the proton elastic form factors ($\mu_pG_E/G_M$) using Rosenbluth separation and those using polarization-based techniques show a strong discrepancy, which has persisted both in modern experimental results and…
Fast procedures for the beam quality assessment and for the monitoring of beam energy modulations during the irradiation are among the most urgent improvements in particle therapy. Indeed, the online measurement of the particle beam energy…
Statistical models for proteomics data often estimate protein fold changes between two samples, A and B, as the average peptide intensity from sample A divided by the average peptide intensity from sample B. Such average intensity ratios…