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Persistent homology is a tool of topological data analysis that has been used in a variety of settings to characterize different dimensional holes in data. However, persistent homology computations can be memory intensive with a…

Algebraic Topology · Mathematics 2024-10-04 Chenghui Li , Jessi Cisewski-Kehe

Identifying molecular signatures from complex disease patients with underlying symptomatic similarities is a significant challenge in the analysis of high dimensional multi-omics data. Topological data analysis (TDA) provides a way of…

Genomics · Quantitative Biology 2024-04-23 Davide Gurnari , Aldo Guzmán-Sáenz , Filippo Utro , Aritra Bose , Saugata Basu , Laxmi Parida

Topological Data Analysis (TDA) has emerged as a powerful framework for extracting robust, multiscale, and interpretable features from complex molecular data for artificial intelligence (AI) modeling and topological deep learning (TDL).…

Biomolecules · Quantitative Biology 2025-09-23 JunJie Wee , Jian Jiang

A primary hypothesis that drives scientific and engineering studies is that data has structure. The dominant paradigms for describing such structure are statistics (e.g., moments, correlation functions) and signal processing (e.g.,…

Algebraic Topology · Mathematics 2020-11-11 Alexander D. Smith , Pawel Dlotko , Victor M. Zavala

Over the last two decades, topological data analysis (TDA) has emerged as a very powerful data analytic approach which can deal with various data modalities of varying complexities. One of the most commonly used tools in TDA is persistent…

Methodology · Statistics 2025-12-08 Anass El Yaagoubi Bourakna , Moo K. Chung , Hernando Ombao

Many datasets can be viewed as a noisy sampling of an underlying space, and tools from topological data analysis can characterize this structure for the purpose of knowledge discovery. One such tool is persistent homology, which provides a…

Modern representation learning increasingly relies on unsupervised and self-supervised methods trained on large-scale unlabeled data. While these approaches achieve impressive generalization across tasks and domains, evaluating embedding…

In recent years, cosmic shear has emerged as a powerful tool to study the statistical distribution of matter in our Universe. Apart from the standard two-point correlation functions, several alternative methods like peak count statistics…

Cosmology and Nongalactic Astrophysics · Physics 2021-04-21 Sven Heydenreich , Benjamin Brück , Joachim Harnois-Déraps

Persistent homology analysis provides means to capture the connectivity structure of data sets in various dimensions. On the mathematical level, by defining a metric between the objects that persistence attaches to data sets, we can…

Machine Learning · Computer Science 2019-06-12 Henri Riihimäki , José Licón-Saláiz

This paper presents a new clustering algorithm for space-time data based on the concepts of topological data analysis and in particular, persistent homology. Employing persistent homology - a flexible mathematical tool from algebraic…

Machine Learning · Statistics 2019-10-28 Umar Islambekov , Yulia Gel

A central challenge in hydrodynamic turbulence is identifying precisely when, and at which length scales, strong turbulent fluctuations (STFs) emerge and develop into intermittent events, which are often obscured by conventional statistical…

We develop a framework for analyzing multivariate time series using topological data analysis (TDA) methods. The proposed methodology involves converting the multivariate time series to point cloud data, calculating Wasserstein distances…

Algebraic Topology · Mathematics 2020-12-29 Chengyuan Wu , Carol Anne Hargreaves

Phenomenological (P-type) bifurcations are qualitative changes in stochastic dynamical systems whereby the stationary probability density function (PDF) changes its topology. The current state of the art for detecting these bifurcations…

Algebraic Topology · Mathematics 2024-06-10 Sunia Tanweer , Firas A. Khasawneh

Persistent homology is a powerful mathematical tool that summarizes useful information about the shape of data allowing one to detect persistent topological features while one adjusts the resolution. However, the computation of such…

Quantum Physics · Physics 2022-03-01 Bernardo Ameneyro , Vasileios Maroulas , George Siopsis

Controlling structural complexity, particularly the number of holes, remains a fundamental challenge in topology optimization, with significant implications for both theoretical analysis and manufacturability. Most existing approaches rely…

Optimization and Control · Mathematics 2026-02-17 Gengchen Li , Depeng Gao , Wenliang Yin , Hongwei Lin

We explore the evolution of daily returns of four major US stock market indices during the technology crash of 2000, and the financial crisis of 2007-2009. Our methodology is based on topological data analysis (TDA). We use persistence…

Mathematical Finance · Quantitative Finance 2017-11-22 Marian Gidea , Yuri Katz

Persistent homology has been devised as a promising tool for the topological simplification of complex data. However, it is computationally intractable for large data sets. In this work, we introduce multiresolution persistent homology for…

Biomolecules · Quantitative Biology 2015-04-02 Kelin Xia , Zhixiong Zhao , Guo-Wei Wei

Persistent homology barcodes and diagrams are a cornerstone of topological data analysis that capture the "shape" of a wide range of complex data structures, such as point clouds, networks, and functions. However, their use in statistical…

Algebraic Topology · Mathematics 2024-09-24 Qiquan Wang , Inés García-Redondo , Pierre Faugère , Gregory Henselman-Petrusek , Anthea Monod

By their nature it is difficult to differentiate chaotic dynamical systems through measurement. In recent years, work has begun on using methods of Topological Data Analysis (TDA) to qualitatively type dynamical data by approximating the…

Algebraic Topology · Mathematics 2026-04-14 Tobias Timofeyev , Christopher Potvin , Benjamin Jones , Kristin M. Kurianski , Miguel Lopez , Sunia Tanweer

Topological statistics, in the form of persistence diagrams, are a class of shape descriptors that capture global structural information in data. The mapping from data structures to persistence diagrams is almost everywhere differentiable,…

Machine Learning · Statistics 2021-02-24 Elchanan Solomon , Alexander Wagner , Paul Bendich
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