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Multiple Sclerosis (MS) is a chronic autoimmune and inflammatory neurological disorder characterised by episodes of symptom exacerbation, known as relapses. In this study, we investigate the role of environmental factors in relapse…

In causal inference, it is common to estimate the causal effect of a single treatment variable on an outcome. However, practitioners may also be interested in the effect of simultaneous interventions on multiple covariates of a fixed target…

Methodology · Statistics 2022-11-24 Jaime Roquero Gimenez , Dominik Rothenhäusler

Air pollution remains a leading global health and environmental risk, particularly in regions vulnerable to episodic air pollution spikes due to wildfires, urban haze and dust storms. Accurate forecasting of particulate matter (PM)…

Air pollution, particularly airborne particulate matter (PM), poses a significant threat to public health globally. It is crucial to comprehend the association between PM-associated toxic components and their cellular targets in humans to…

Machine Learning · Computer Science 2024-12-24 Yan Zhu , Shihao Wang , Yong Han , Yao Lu , Shulan Qiu , Ling Jin , Xiangdong Li , Weixiong Zhang

In recent years, many methods have been developed for detecting causal relationships in observational data. Some of them have the potential to tackle large data sets. However, these methods fail to discover a combined cause, i.e. a…

Artificial Intelligence · Computer Science 2015-10-16 Saisai Ma , Jiuyong Li , Lin Liu , Thuc Duy Le

Mendelian Randomization is a widely used instrumental variable method for assessing causal effects of lifelong exposures on health outcomes. Many exposures, however, have causal effects that vary across the life course and often influence…

Air pollution is a worldwide public health threat that can cause or exacerbate many illnesses, including respiratory disease, cardiovascular disease, and some cancers. However, epidemiological studies and public health decision-making are…

Fine particulate matter (PM2.5) measured at a given location is a mix of pollution generated locally and pollution traveling long distances in the atmosphere. Therefore, the identification of spatial scales associated with health effects…

Methodology · Statistics 2016-09-19 Joseph Antonelli , Joel Schwartz , Itai Kloog , Brent Coull

Wildfires have become one of the biggest natural hazards for environments worldwide. The effects of wildfires are heterogeneous, meaning that the magnitude of their effects depends on many factors such as geographical region, climate and…

Applications · Statistics 2021-05-10 Feliu Serra-Burriel , Pedro Delicado , Andrew T. Prata , Fernando M. Cucchietti

Accurate estimation of counterfactual outcomes in high-dimensional data is crucial for decision-making and understanding causal relationships and intervention outcomes in various domains, including healthcare, economics, and social…

Machine Learning · Computer Science 2024-07-31 Jiageng Zhu , Hanchen Xie , Jiazhi Li , Wael Abd-Almageed

Accurate air quality forecasting is essential for public health and environmental sustainability, but remains challenging due to the complex pollutant dynamics. Existing deep learning methods often model pollutant dynamics as an…

Machine Learning · Computer Science 2026-03-19 Binqing Wu , Zongjiang Shang , Shiyu Liu , Jianlong Huang , Jiahui Xu , Ling Chen

Causal inference is a fundamental research topic for discovering the cause-effect relationships in many disciplines. However, not all algorithms are equally well-suited for a given dataset. For instance, some approaches may only be able to…

Machine Learning · Computer Science 2024-03-11 Zhipeng Ma , Marco Kemmerling , Daniel Buschmann , Chrismarie Enslin , Daniel Lütticke , Robert H. Schmitt

Analyzing air pollution data is challenging as there are various analysis focuses from different aspects: feature (what), space (where), and time (when). As in most geospatial analysis problems, besides high-dimensional features, the…

Machine Learning · Computer Science 2022-02-14 Yun-Hsin Kuo , Takanori Fujiwara , Charles C. -K. Chou , Chun-houh Chen , Kwan-Liu Ma

The increasing size and severity of wildfires across the western United States have generated dangerous levels of PM$_{2.5}$ concentrations in recent years. In a changing climate, expanding the use of prescribed fires is widely considered…

Atmospheric and Oceanic Physics · Physics 2024-05-27 Kyleen Liao , Jatan Buch , Kara Lamb , Pierre Gentine

Air pollution remains a leading global health threat, with fine particulate matter (PM2.5) contributing to millions of premature deaths annually. Chemical transport models (CTMs) are essential tools for evaluating how emission controls…

Atmospheric and Oceanic Physics · Physics 2025-06-24 Shigan Liu , Guannan Geng , Yanfei Xiang , Hejun Hu , Xiaodong Liu , Xiaomeng Huang , Qiang Zhang

In causal inference, and specifically in the \textit{Causes of Effects} problem, one is interested in how to use statistical evidence to understand causation in an individual case, and so how to assess the so-called {\em probability of…

Methodology · Statistics 2018-10-23 Fabio Corradi , Monica Musio

A causal decomposition analysis allows researchers to determine whether the difference in a health outcome between two groups can be attributed to a difference in each group's distribution of one or more modifiable mediator variables. With…

Methodology · Statistics 2024-08-09 Melissa J. Smith , Leslie A. McClure , D. Leann Long

We develop new matching estimators for estimating causal quantile exposure-response functions and quantile exposure effects with continuous treatments. We provide identification results for the parameters of interest and establish the…

Methodology · Statistics 2023-08-04 Luca Merlo , Francesca Dominici , Lea Petrella , Nicola Salvati , Xiao Wu

The use of genetic variants as instrumental variables - an approach known as Mendelian randomization - is a popular epidemiological method for estimating the causal effect of an exposure (phenotype, biomarker, risk factor) on a disease or…

Methodology · Statistics 2020-12-21 Ioan Gabriel Bucur , Tom Claassen , Tom Heskes

Wildfires are uncontrolled fires in the environment that can be caused by humans or nature. In 2020 alone, wildfires in California have burned 4.2 million acres, damaged 10,500 buildings or structures, and killed more than 31 people,…

Computer Vision and Pattern Recognition · Computer Science 2021-09-14 Samarth Shah