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Current quantum programs are mostly synthesized and compiled on the gate-level, where quantum circuits are composed of quantum gates. The gate-level workflow, however, introduces significant redundancy when quantum gates are eventually…

Many quantum algorithms make use of oracles which evaluate classical functions on a superposition of inputs. In order to facilitate implementation, testing, and resource estimation of such algorithms, we present quantum circuits for…

Quantum Physics · Physics 2018-06-01 Thomas Häner , Martin Roetteler , Krysta M. Svore

Quantum computing is a game-changing technology for global academia, research centers and industries including computational science, mathematics, finance, pharmaceutical, materials science, chemistry and cryptography. Although it has seen…

Quantum Physics · Physics 2023-03-07 He-Liang Huang , Xiao-Yue Xu , Chu Guo , Guojing Tian , Shi-Jie Wei , Xiaoming Sun , Wan-Su Bao , Gui-Lu Long

We consider quantum-classical hybrid machine learning in which large-scale input channels remain classical and small-scale working channels process quantum operations conditioned on classical input data. This does not require the conversion…

The integration of high-penetration renewable energy introduces significant stochasticity and non-convexity into power system dispatching, challenging the computational limits of classical optimization. While Variational Quantum Algorithms…

Quantum Physics · Physics 2026-01-27 Fu Zhang , Yuming Zhao

The rapid development of quantum computing (QC) in the NISQ era urgently demands a low-level benchmark suite and insightful evaluation metrics for characterizing the properties of prototype NISQ devices, the efficiency of QC programming…

Quantum Physics · Physics 2022-05-10 Ang Li , Samuel Stein , Sriram Krishnamoorthy , James Ang

Major players in the global aerospace industry are shifting their focus toward achieving net carbon-neutral operations by 2050. A considerable portion of the overall carbon emission reduction is expected to come from new aircraft…

Fault tolerance is a long-term objective driving many companies and research organizations to compete in making current, imperfect quantum computers useful - Quantum Utility (QU). It looks promising to achieve this by leveraging software…

Quantum Physics · Physics 2024-09-27 Markiian Tsymbalista , Ihor Katernyak

High-Performance Computing (HPC) systems are the most powerful tools that we currently have to solve complex scientific simulations. Quantum computing (QC) has the potential to enhance HPC systems by accelerating the execution of specific…

Accurate financial volatility forecasting is crucial but challenged by the non-linear, highly correlated nature of market data. Recently, quantum computing has emerged as a promising paradigm for solving complex high-dimensional sampling…

Machine Learning · Computer Science 2026-05-07 Yixiong Chen

Reliably executing quantum algorithms on noisy intermediate-scale quantum (NISQ) devices is challenging, as they are severely constrained and prone to errors. Efficient quantum circuit compilation techniques are therefore crucial for…

It is one of the most fundamental objectives in quantum information science to understand the boundary between the computational power of classical and quantum computers. One possible avenue to explore this boundary is to identify classes…

Quantum Physics · Physics 2025-03-28 Christophe Piveteau

Present-day quantum systems face critical bottlenecks, including limited qubit counts, brief coherence intervals, and high susceptibility to errors-all of which obstruct the execution of large and complex circuits. The advancement of…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-06-13 Waylon Luo , Jiapeng Zhao , Tong Zhan , Qiang Guan

We introduce hybrid sequential quantum computing (HSQC), a paradigm for combinatorial optimization that systematically integrates classical and quantum methods within a structured, stage-wise workflow. HSQC may involve an arbitrary sequence…

Accurate prediction of protein active-site structures remains a central challenge in structural biology, particularly for short and flexible peptide fragments where conventional and simulation-based methods often fail. Here, we present a…

For quantum algorithms for problems in which the task is to compute an entire field of values, like e.g. computational fluid dynamics (CFD), it is often proposed amplitude encoding w.r.t. multiple qubits; however, the efforts implied by it…

Quantum Physics · Physics 2026-04-08 Hans A. Kösel , Roland Ewert , Jan W. Delfs

Variational quantum algorithms provide a direct, physics-based approach to protein structure prediction, but their accuracy is limited by the coarse resolution of the energy landscapes generated on current noisy devices. We propose a hybrid…

Emerging Technologies · Computer Science 2025-10-09 Yuqi Zhang , Yuxin Yang , Feixiong Chen , Cheng-Chang Lu , Nima Saeidi , Samuel L. Volchenboum , Junhan Zhao , Siwei Chen , Weiwen Jiang , Qiang Guan

Quantum annealing (QA) has the potential to significantly improve solution quality and reduce time complexity in solving combinatorial optimization problems compared to classical optimization methods. However, due to the limited number of…

Quantum Physics · Physics 2025-04-09 Seongmin Kim , Sang-Woo Ahn , In-Saeng Suh , Alexander W. Dowling , Eungkyu Lee , Tengfei Luo

Building a quantum computer that surpasses the computational power of its classical counterpart is a great engineering challenge. Quantum software optimizations can provide an accelerated pathway to the first generation of quantum computing…

Scaling bottlenecks the making of digital quantum computers, posing challenges from both the quantum and the classical components. We present a classical architecture to cope with a comprehensive list of the latter challenges {\em all at…