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Quantum convolutional neural networks (QCNNs) offer a promising architecture for near-term quantum machine learning by combining hierarchical feature extraction with modest parameter growth. However, any QCNN operating on classical data…

Quantum Physics · Physics 2025-12-16 Xingyun Feng

A large class of problems in the current era of quantum devices involve interfacing between the quantum and classical system. These include calibration procedures, characterization routines, and variational algorithms. The control in these…

For many practical applications of quantum computing, the most costly steps involve coherently accessing classical data. We help address this challenge by applying mass production techniques, which can reduce the cost of applying an…

Quantum Physics · Physics 2025-06-03 William J. Huggins , Tanuj Khattar , Nathan Wiebe

Powerful hardware services and software libraries are vital tools for quickly and affordably designing, testing, and executing quantum algorithms. A robust large-scale study of how the performance of these platforms scales with the number…

The connection and eventual integration of High-Performance Computing (HPC) with Quantum Computing (QC) represents a transformative advancement in computational technology, promising significant enhancements in solving complex, previously…

Quantum assembly languages are machine-independent languages that traditionally describe quantum computation in the circuit model. Open quantum assembly language (OpenQASM 2) was proposed as an imperative programming language for quantum…

The increasing control complexity of Noisy Intermediate-Scale Quantum (NISQ) systems underlines the necessity of integrating quantum hardware with quantum software. While mapping heterogeneous quantum-classical computing (HQCC) algorithms…

Quantum Physics · Physics 2021-08-10 The Quingo Development Team

Integer programming (IP) is an NP-hard combinatorial optimization problem that is widely used to represent a diverse set of real-world problems spanning multiple fields, such as finance, engineering, logistics, and operations research. It…

Quantum Physics · Physics 2025-08-20 Kapil Goswami , Peter Schmelcher , Rick Mukherjee

To address the urgent need in the NISQ era for high-performance, scalable quantum compilers and to advance the integration of classical and quantum computing, we present QLLVM, an advanced Quantum-Classical co-compilation framework built on…

Quantum Physics · Physics 2026-04-17 Yu Zhu , Qiming Du , Yuqiong Jin , Woji He , Hang Lian , Xin Zhou , Jinchen Xu , Zheng Shan

AlphaFold has achieved groundbreaking advancements in protein structure prediction, exerting profound influence across biology, medicine, and drug discovery. However, its reliance on multiple sequence alignment (MSA) is inherently…

Quantum Physics · Physics 2025-06-03 Rong Chen , Quan-Xin Mei , Wen-Ding Zhao , Lin Yao , Hao-Xiang Yang , Shun-Yao Zhang , Jiao Chen , Hong-Lin Li

Quantum interior point methods (QIPMs) promise polynomial speed-ups over classical solvers for linear programming by outsourcing the solution of Newton linear systems to quantum linear solvers (QLSAs). However, asymptotic speed-ups do not…

Quantum Physics · Physics 2026-04-28 Lennart Binkowski

In the near-term noisy intermediate-scale quantum (NISQ) era, high noise will significantly reduce the fidelity of quantum computing. Besides, the noise on quantum devices is not stable. This leads to a challenging problem: At run-time, is…

Quantum Physics · Physics 2023-09-13 Zhirui Hu , Robert Wolle , Mingzhen Tian , Qiang Guan , Travis Humble , Weiwen Jiang

Quantum computers face challenges due to limited resources, particularly in cloud environments. Despite these obstacles, Variational Quantum Algorithms (VQAs) are considered promising applications for present-day Noisy Intermediate-Scale…

Quantum Physics · Physics 2024-12-18 Meng Wang , Poulami Das , Prashant J. Nair

Quantum computing promises speedup of classical algorithms in the long term. Current hardware is unable to support this goal and programs must be efficiently compiled to use of the devices through reduction of qubits used, gate count and…

Quantum Physics · Physics 2022-11-30 Andrew Litteken , Jonathan M. Baker , Frederic T. Chong

While real quantum devices have been increasingly used to conduct research focused on achieving quantum advantage or quantum utility in recent years, executing deep quantum circuits or performing quantum machine learning with large-scale…

Quantum Physics · Physics 2026-04-06 Yoshiaki Kawase

Quantum computing has garnered attention for its potential to solve complex computational problems with considerable speedup. Despite notable advancements in the field, achieving meaningful scalability and noise control in quantum hardware…

Quantum Physics · Physics 2025-05-12 Eduardo Willwock Lussi , Rafael de Santiago , Eduardo Inacio Duzzioni

While quantum computing holds immense potential for tackling previously intractable problems, its current practicality remains limited. A critical aspect of realizing quantum utility is the ability to efficiently interface with data from…

Emerging Technologies · Computer Science 2025-02-03 Sudhanshu Pravin Kulkarni , Daniel E. Huang , E. Wes Bethel

We present PINNACLE, an open-source computational framework for physics-informed neural networks (PINNs) that integrates modern training strategies, multi-GPU acceleration, and hybrid quantum-classical architectures within a unified modular…

Machine Learning · Computer Science 2026-04-20 Shimon Pisnoy , Hemanth Chandravamsi , Ziv Chen , Aaron Goldgewert , Gal Shaviner , Boris Shragner , Steven H. Frankel

In the NISQ-era of quantum computing, we should not expect to see quantum devices that provide an exponential improvement in runtime for practical problems, due to the lack of error correction and small number of qubits available.…

Quantum Physics · Physics 2019-07-02 Samuel S. Mendelson , Robert W. Strand , Guy B. Oldaker , Jacob M. Farinholt

This paper introduces a vision for Quantum Software Development lifecycle, proposing a hybrid full-stack iterative model that integrates quantum and classical computing. Addressing the current challenges in Quantum Computing (QC) such as…

Software Engineering · Computer Science 2025-04-09 Arif Ali Khan , Davide Taibi , Muhammad Azeem Akbar