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This chapter revisits the concept of excitability, a basic system property of neurons. The focus is on excitable systems regarded as behaviors rather than dynamical systems. By this we mean open systems modulated by specific interconnection…

Neurons and Cognition · Quantitative Biology 2017-04-18 Rodolphe Sepulchre , Guillaume Drion , Alessio Franci

An electronic circuit device, inspired on the FitzHugh-Nagumo model of neuronal excitability, was constructed and shown to operate with characteristics compatible with those of biological sensory neurons. The nonlinear dynamical model of…

The threshold voltage for action potential generation is a key regulator of neuronal signal transduction, yet the mechanism of its dynamic variation is still not well described. In this paper, we propose that threshold phenomena can be…

Neurons and Cognition · Quantitative Biology 2019-11-22 Longfei Wang , Hengtong Wang , Lianchun Yu , Yong Chen

We describe a chain of unidirectionally coupled adaptive excitable elements slowly driven by a stochastic process from one end and open at the other end, as a minimal toy model of unresolved irreducible uncertainty in a system performing…

Neurons and Cognition · Quantitative Biology 2022-09-14 Mario Martinez-Saito

In this work we investigate the phenomena associated with the new thresholds in the spectrum of excitations arising when different one-dimensional strongly interacting systems are voltage biased and weakly coupled by tunneling. We develop…

Mesoscale and Nanoscale Physics · Physics 2019-02-27 Artem Borin , Eugene Sukhorukov

The describing function (DF) and phase response curve (PRC) are classical tools for the analysis of feedback oscillations and rhythmic behaviors, widely used across control engineering, biology, and neuroscience. These tools are known to…

Systems and Control · Electrical Eng. & Systems 2025-11-27 Robin Wroblowski , Rodolphe Sepulchre

We define a characteristic energy density based on the measurement of the two first moments of the extrinsic injected power smoothed over time. Using the stationarity, we show that this definition characterizes an energy per degrees freedom…

Statistical Mechanics · Physics 2018-07-06 Sebastien Aumaitre , Antoine Naert

A recurrent idea in the study of complex systems is that optimal information processing is to be found near bifurcation points or phase transitions. However, this heuristic hypothesis has few (if any) concrete realizations where a standard…

Neurons and Cognition · Quantitative Biology 2007-05-23 Osame Kinouchi , Mauro Copelli

The convergence properties of adaptive systems in terms of excitation conditions on the regressor vector are well known. With persistent excitation of the regressor vector in model reference adaptive control the state error and the…

Optimization and Control · Mathematics 2015-11-11 Benjamin M. Jenkins , Anuradha M. Annaswamy , Eugene Lavretsky , Travis E. Gibson

The analyses presented herein demonstrate that neuronal electrical activity can be consistently interpreted as a manifestation of murburn redox-mediated electronic dynamics rather than as a process fundamentally driven by transmembrane…

Neurons and Cognition · Quantitative Biology 2026-05-04 Kelath Murali Manoj , Nagamani Sukumar

Neuronal excitability is the phenomena that describes action potential generation due to a stimulus input. Commonly, neuronal excitability is divided into two classes: Type I and Type II, both having different properties that affect…

Neurons and Cognition · Quantitative Biology 2020-11-03 Jantine A. C. Broek , Guillaume Drion

The animal nervous system offers a model of computation combining digital reliability and analog efficiency. Understanding how this sweet spot can be realized is a core question of neuromorphic engineering. To this aim, this paper explores…

Systems and Control · Electrical Eng. & Systems 2026-02-19 Michelangelo Bin , Alessandro Cecconi , Lorenzo Marconi

Unlike many physical nonequilibrium systems, in biological systems, the coupling to external energy sources is not a fixed parameter but adaptively controlled by the system itself. We do not have theoretical frameworks that allow for such…

Populations and Evolution · Quantitative Biology 2025-06-30 Ankit Dhanuka , Avi I. Flamholz , Arvind Murugan , Akshit Goyal

Dissipativity is an essential concept of systems theory. The paper provides an extension of dissipativity, named differential dissipativity, by lifting storage functions and supply rates to the tangent bundle. Differential dissipativity is…

Systems and Control · Computer Science 2013-05-17 Fulvio Forni , Rodolphe Sepulchre

Excitable membranes are an important type of nonlinear dynamical system and their study can be used to provide a connection between physical and biological circuits. We discuss two models of excitable membranes important in cardiac and…

Biological Physics · Physics 2012-12-18 Jarrett L. Lancaster , Esther M. Leise , Edward H. Hellen

I show how transition systems can be applied to the naturally concurrent behaviour of excitable media. I consider structured excitable media, in which excitations are constrained to propagate only in defined narrow channels, and cannot…

Pattern Formation and Solitons · Physics 2012-11-27 William M. Stevens

We extend the scope of the dynamical theory of extreme values to cover phenomena that do not happen instantaneously, but evolve over a finite, albeit unknown at the onset, time interval. We consider complex dynamical systems, composed of…

Neurons and Cognition · Quantitative Biology 2020-05-20 Theophile Caby , Giorgio Mantica

We study deterministic systems, composed of excitable units of FitzHugh-Nagumo type, that are capable of self-generating and self-terminating strong deviations from their regular dynamics without the influence of noise or parameter change.…

Chaotic Dynamics · Physics 2014-08-28 Gerrit Ansmann , Rajat Karnatak , Klaus Lehnertz , Ulrike Feudel

A novel model of analyzing Schmitt trigger as 2 level (metastable/stable) energy system is presented. The energy of the 2 level system is identified. In an MOS implementation, this arises from the electrostatic potential energy of the…

Classical Physics · Physics 2016-12-13 Bosco Leung , Yon Chiet Ng , Safieddin Safavi-Naeini

Depending on context, the term entropy is used for a thermodynamic quantity, a~measure of available choice, a quantity to measure information, or, in the context of statistical inference, a maximum configuration predictor. For systems in…

Statistical Mechanics · Physics 2018-11-14 Rudolf Hanel , Stefan Thurner
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