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Large Language Models (LLMs) show promise in biomedicine but lack true causal understanding, relying instead on correlations. This paper envisions causal LLM agents that integrate multimodal data (text, images, genomics, etc.) and perform…

Artificial Intelligence · Computer Science 2025-05-23 Adib Bazgir , Amir Habibdoust Lafmajani , Yuwen Zhang

Intelligent systems have traditionally been designed as tools rather than collaborators, often lacking critical characteristics that collaboration partnerships require. Recent advances in large language model (LLM) agents open new…

Human-Computer Interaction · Computer Science 2026-02-17 Bingsheng Yao , Jiaju Chen , Chaoran Chen , April Wang , Toby Jia-jun Li , Dakuo Wang

Recent advances on large language models (LLMs) enable researchers and developers to build autonomous language agents that can automatically solve various tasks and interact with environments, humans, and other agents using natural language…

Simulations, although powerful in accurately replicating real-world systems, often remain inaccessible to non-technical users due to their complexity. Conversely, large language models (LLMs) provide intuitive, language-based interactions…

Computation and Language · Computer Science 2025-05-22 Jacob Kleiman , Kevin Frank , Joseph Voyles , Sindy Campagna

Large language models (LLMs) have significantly advanced in various fields and intelligent agent applications. However, current LLMs that learn from human or external model supervision are costly and may face performance ceilings as task…

Computation and Language · Computer Science 2024-06-04 Zhengwei Tao , Ting-En Lin , Xiancai Chen , Hangyu Li , Yuchuan Wu , Yongbin Li , Zhi Jin , Fei Huang , Dacheng Tao , Jingren Zhou

Large language models (LLMs) are increasingly used in scientific research and discovery, supporting tasks ranging from literature retrieval and synthesis to hypothesis generation, autonomous experimentation, and research evaluation.…

Digital Libraries · Computer Science 2026-05-13 Haoxuan Zhang , Ruochi Li , Yang Zhang , Ting Xiao , Jiangping Chen , Junhua Ding , Haihua Chen

Design patterns have been used in various fields of inquiry and endeavour to externalize procedural knowledge in a form that supports human reasoning and coordination. In this paper, we show that contemporary Large Language Model…

Human-Computer Interaction · Computer Science 2026-02-05 Joseph Corneli , Charles J. Danoff , Raymond S. Puzio , Sridevi Ayloo , Sergio Belich , Andre Wilkinson , Mary Tedeschi , Pauline Mosley

Large language models have enabled agentic systems that reason, plan, and interact with tools and environments to accomplish complex tasks. As these agents operate over extended interaction horizons, their effectiveness increasingly depends…

Artificial Intelligence · Computer Science 2026-03-17 Yue Xu , Qian Chen , Zizhan Ma , Dongrui Liu , Wenxuan Wang , Xiting Wang , Li Xiong , Wenjie Wang

Autonomous agents empowered by Large Language Models (LLMs) have undergone significant improvements, enabling them to generalize across a broad spectrum of tasks. However, in real-world scenarios, cooperation among individuals is often…

With the continuous development of large language models (LLMs), transformer-based models have made groundbreaking advances in numerous natural language processing (NLP) tasks, leading to the emergence of a series of agents that use LLMs as…

Artificial Intelligence · Computer Science 2024-11-15 Yuyou Gan , Yong Yang , Zhe Ma , Ping He , Rui Zeng , Yiming Wang , Qingming Li , Chunyi Zhou , Songze Li , Ting Wang , Yunjun Gao , Yingcai Wu , Shouling Ji

Memory emerges as the core module in the large language model (LLM)-based agents for long-horizon complex tasks (e.g., multi-turn dialogue, game playing, scientific discovery), where memory can enable knowledge accumulation, iterative…

Computation and Language · Computer Science 2026-05-04 Yanchen Wu , Tenghui Lin , Yingli Zhou , Fangyuan Zhang , Qintian Guo , Xun Zhou , Sibo Wang , Xilin Liu , Yuchi Ma , Yixiang Fang

This paper investigates the integration of cognitive agents powered by Large Language Models (LLMs) within the Scaled Agile Framework (SAFe) to reinforce software project management. By deploying virtual agents in simulated software…

Software Engineering · Computer Science 2025-08-26 Konrad Cinkusz , Jarosław A. Chudziak , Ewa Niewiadomska-Szynkiewicz

Modern Large Language Models (LLMs) exhibit impressive zero-shot and few-shot generalization capabilities across complex natural language tasks, enabling their widespread use as virtual assistants for diverse applications such as…

Computation and Language · Computer Science 2025-06-19 Arjun Vaithilingam Sudhakar

Large language models (LLMs) and vision-language models (VLMs) have the potential to transform biological research by enabling autonomous experimentation. Yet, their application remains constrained by rigid protocol design, limited…

Robotics · Computer Science 2025-07-03 Yibo Qiu , Zan Huang , Zhiyu Wang , Handi Liu , Yiling Qiao , Yifeng Hu , Shu'ang Sun , Hangke Peng , Ronald X Xu , Mingzhai Sun

This review critically distinguishes between AI Agents and Agentic AI, offering a structured, conceptual taxonomy, application mapping, and analysis of opportunities and challenges to clarify their divergent design philosophies and…

Artificial Intelligence · Computer Science 2025-10-01 Ranjan Sapkota , Konstantinos I. Roumeliotis , Manoj Karkee

The focus of AI development has shifted from academic research to practical applications. However, AI development faces numerous challenges at various levels. This article will attempt to analyze the opportunities and challenges of AI from…

Artificial Intelligence · Computer Science 2026-01-06 Bor-Sung Liang

Large Language Models (LLMs) have revolutionized Natural Language Processing but exhibit limitations, particularly in autonomously addressing novel challenges such as reasoning and problem-solving. Traditional techniques like…

Multiagent Systems · Computer Science 2024-01-03 Sumedh Rasal

The advent of large language models (LLMs), such as GPT, Gemini, and DeepSeek, has significantly advanced natural language processing, giving rise to sophisticated chatbots capable of diverse language-related tasks. The transition from…

Computation and Language · Computer Science 2025-06-16 Jiachen Zhu , Menghui Zhu , Renting Rui , Rong Shan , Congmin Zheng , Bo Chen , Yunjia Xi , Jianghao Lin , Weiwen Liu , Ruiming Tang , Yong Yu , Weinan Zhang

Cybersecurity has become one of the earliest adopters of agentic AI, as security operations centers increasingly rely on multi-step reasoning, tool-driven analysis, and rapid decision-making under pressure. While individual large language…

Cryptography and Security · Computer Science 2025-12-09 Vaishali Vinay

The rapid development of large language model (LLM)-based agents has unlocked new possibilities for autonomous multi-turn reasoning and tool-augmented decision-making. However, their real-world deployment is hindered by severe…