Related papers: De Novo Molecular Design Enabled by Direct Prefere…
Traditional RLHF-based LLM alignment methods explicitly maximize the expected rewards from a separate reward model. More recent supervised alignment methods like Direct Preference Optimization (DPO) circumvent this phase to avoid problems…
Multimodal Large Language Models (MLLMs) have significantly improved the performance of various tasks, but continue to suffer from visual hallucinations, a critical issue where generated responses contradict visual evidence. While Direct…
A major challenge in aligning large language models (LLMs) with human preferences is the issue of distribution shift. LLM alignment algorithms rely on static preference datasets, assuming that they accurately represent real-world user…
We study inventory control policies for pharmaceutical supply chains, addressing challenges such as perishability, yield uncertainty, and non-stationary demand, combined with batching constraints, lead times, and lost sales. Collaborating…
Generating visually appealing images is fundamental to modern text-to-image generation models. A potential solution to better aesthetics is direct preference optimization (DPO), which has been applied to diffusion models to improve general…
With the rapid advancement of large language models (LLMs), aligning policy models with human preferences has become increasingly critical. Direct Preference Optimization (DPO) has emerged as a promising approach for alignment, acting as an…
Direct Preference Optimization (DPO) has emerged as a cornerstone of reinforcement learning from human feedback (RLHF) due to its simplicity and efficiency. However, existing DPO-based methods typically treat all preference pairs equally,…
Recent advancements in Direct Preference Optimization (DPO) have significantly enhanced the alignment of Large Language Models (LLMs) with human preferences, owing to its simplicity and effectiveness. However, existing methods typically…
Large Language Models (LLMs) as autonomous agents are increasingly tasked with solving complex, long-horizon problems. Aligning these agents via preference-based offline methods like Direct Preference Optimization (DPO) is a promising…
Recent developments in Direct Preference Optimization (DPO) allow large language models (LLMs) to function as implicit ranking models by maximizing the margin between preferred and non-preferred responses. In practice, user feedback on such…
Recommender systems aim to predict personalized rankings based on user preference data. With the rise of Language Models (LMs), LM-based recommenders have been widely explored due to their extensive world knowledge and powerful reasoning…
We introduce Direct Value Optimization (DVO), an innovative reinforcement learning framework for enhancing large language models in complex reasoning tasks. Unlike traditional methods relying on preference labels, DVO utilizes value signals…
In the field of Structure-based Drug Design (SBDD), deep learning-based generative models have achieved outstanding performance in terms of docking score. However, further study shows that the existing molecular generative methods and…
Diffusion policies, widely adopted in decision-making scenarios such as robotics, gaming and autonomous driving, are capable of learning diverse skills from demonstration data due to their high representation power. However, the sub-optimal…
Direct Preference Optimization (DPO) has been proposed as a promising alternative to Proximal Policy Optimization (PPO) based Reinforcement Learning with Human Feedback (RLHF). However, empirical evaluations consistently reveal suboptimal…
This work introduces a method to tune a sequence-based generative model for molecular de novo design that through augmented episodic likelihood can learn to generate structures with certain specified desirable properties. We demonstrate how…
Group Relative Policy Optimization(GRPO) has become a cornerstone of modern reinforcement learning alignment, prized for its efficacy in foregoing an explicit value-critic by leveraging reward normalization across sampled trajectory…
The ultimate goal of drug design is to find novel compounds with desirable pharmacological properties. Designing molecules retaining particular scaffolds as the core structures of the molecules is one of the efficient ways to obtain…
Direct Preference Optimization (DPO) has become a prominent method for aligning Large Language Models (LLMs) with human preferences. While DPO has enabled significant progress in aligning English LLMs, multilingual preference alignment is…
Recent deep reinforcement learning methods have achieved remarkable success in solving multi-objective combinatorial optimization problems (MOCOPs) by decomposing them into multiple subproblems, each associated with a specific weight…