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Circulating Tumor Cells (CTCs) bear great promise as biomarkers in tumor prognosis. However, the process of identification and later enumeration of CTCs require manual labor, which is error-prone and time-consuming. The recent developments…

Computer Vision and Pattern Recognition · Computer Science 2022-08-08 Elena Alexander , Kam W. Leong , Andrew F. Laine

The hindering problem in facial expression recognition (FER) is the presence of inaccurate annotations referred to as noisy annotations in the datasets. These noisy annotations are present in the datasets inherently because the labeling is…

Computer Vision and Pattern Recognition · Computer Science 2023-05-04 Darshan Gera , Badveeti Naveen Siva Kumar , Bobbili Veerendra Raj Kumar , S Balasubramanian

Deep learning (DL) has recently drawn much attention in image analysis, natural language process, and high-dimensional medical data analysis. Under the causal direct acyclic graph (DAG) interpretation, the input variables without incoming…

Applications · Statistics 2022-03-22 Jong-Hyeon Jeong , Yichen Jia

Deep learning models have shown promising performance for cell nucleus segmentation in the field of pathology image analysis. However, training a robust model from multiple domains remains a great challenge for cell nucleus segmentation.…

Image and Video Processing · Electrical Eng. & Systems 2024-03-12 Dawei Fan , Yifan Gao , Jiaming Yu , Yanping Chen , Wencheng Li , Chuancong Lin , Kaibin Li , Changcai Yang , Riqing Chen , Lifang Wei

Convolutional neural networks can be trained to perform histology slide classification using weak annotations with multiple instance learning (MIL). However, given the paucity of labeled histology data, direct application of MIL can easily…

Computer Vision and Pattern Recognition · Computer Science 2019-11-05 Ming Y. Lu , Richard J. Chen , Jingwen Wang , Debora Dillon , Faisal Mahmood

The evaluation of the Human Epidermal growth factor Receptor-2 (HER2) expression is an important prognostic biomarker for breast cancer treatment selection. However, HER2 scoring has notoriously high interobserver variability due to stain…

Image and Video Processing · Electrical Eng. & Systems 2022-11-18 Manh Dan Pham , Cyprien Tilmant , Stéphanie Petit , Isabelle Salmon , Saima Ben Hadj , Rutger H. J. Fick

Background and Objective: Gastric cancer has turned out to be the fifth most common cancer globally, and early detection of gastric cancer is essential to save lives. Histopathological examination of gastric cancer is the gold standard for…

Computer Vision and Pattern Recognition · Computer Science 2021-11-03 Weiming Hu , Chen Li , Xiaoyan Li , Md Mamunur Rahaman , Jiquan Ma , Yong Zhang , Haoyuan Chen , Wanli Liu , Changhao Sun , Yudong Yao , Hongzan Sun , Marcin Grzegorzek

Using histopathological images to automatically classify cancer is a difficult task for accurately detecting cancer, especially to identify metastatic cancer in small image patches obtained from larger digital pathology scans. Computer…

Image and Video Processing · Electrical Eng. & Systems 2020-11-16 Guanwen Qiu , Xiaobing Yu , Baolin Sun , Yunpeng Wang , Lipei Zhang

This paper explores interpretability techniques for two of the most successful learning algorithms in medical decision-making literature: deep neural networks and random forests. We applied these algorithms in a real-world medical dataset…

Machine Learning · Computer Science 2020-02-24 Catarina Moreira , Renuka Sindhgatta , Chun Ouyang , Peter Bruza , Andreas Wichert

Colorectal cancer (CRC) remains one of the leading causes of cancer-related morbidity and mortality worldwide, with gastrointestinal (GI) polyps serving as critical precursors according to the World Health Organization (WHO). Early and…

Computer Vision and Pattern Recognition · Computer Science 2026-01-15 Akwasi Asare , Thanh-Huy Nguyen , Ulas Bagci

The focus of this work is on Statistical Process Control (SPC) of a manufacturing process based on available measurements. Two important applications of SPC in industrial settings are fault detection and diagnosis (FDD). In this work a deep…

Machine Learning · Computer Science 2022-11-21 Piyush Agarwal , Melih Tamer , Hector Budman

Applying deep learning methods to mammography assessment has remained a challenging topic. Dense noise with sparse expressions, mega-pixel raw data resolution, lack of diverse examples have all been factors affecting performance. The lack…

Computer Vision and Pattern Recognition · Computer Science 2018-07-10 Ulzee An , Khader Shameer , Lakshmi Subramanian

Anomaly detection is the task of recognising novel samples which deviate significantly from pre-establishednormality. Abnormal classes are not present during training meaning that models must learn effective rep-resentations solely across…

Machine Learning · Computer Science 2023-03-08 Jack W Barker , Neelanjan Bhowmik , Yona Falinie A Gaus , Toby P Breckon

We trained and evaluated a localization-based deep CNN for breast cancer screening exam classification on over 200,000 exams (over 1,000,000 images). Our model achieves an AUC of 0.919 in predicting malignancy in patients undergoing breast…

Image and Video Processing · Electrical Eng. & Systems 2019-08-05 Thibault Févry , Jason Phang , Nan Wu , S. Gene Kim , Linda Moy , Kyunghyun Cho , Krzysztof J. Geras

Invasive ductal carcinoma (IDC) is the most prevalent form of breast cancer, and early, accurate diagnosis is critical to improving patient survival rates by guiding treatment decisions. Combining medical expertise with artificial…

Image and Video Processing · Electrical Eng. & Systems 2025-08-12 Shuo Han , Ahmed Karam Eldaly , Solomon Sunday Oyelere

Breast cancer is the second most common cancer among women worldwide. Diagnosis of breast cancer by the pathologists is a time-consuming procedure and subjective. Computer aided diagnosis frameworks are utilized to relieve pathologist…

Computer Vision and Pattern Recognition · Computer Science 2023-08-15 Bahareh Morovati , Reza Lashgari , Mojtaba Hajihasani , Hasti Shabani

Deep models based on vision transformer (ViT) and convolutional neural network (CNN) have demonstrated remarkable performance on natural datasets. However, these models may not be similar in medical imaging, where abnormal regions cover…

Computer Vision and Pattern Recognition · Computer Science 2026-02-11 Ahmad Chaddad , Yihang Wu , Xianrui Chen

Lung nodule malignancy prediction is an essential step in the early diagnosis of lung cancer. Besides the difficulties commonly discussed, the challenges of this task also come from the ambiguous labels provided by annotators, since deep…

Image and Video Processing · Electrical Eng. & Systems 2021-04-26 Zehui Liao , Yutong Xie , Shishuai Hu , Yong Xia

Microscopic examination of slides prepared from tissue samples is the primary tool for detecting and classifying cancerous lesions, a process that is time-consuming and requires the expertise of experienced pathologists. Recent advances in…

Computer Vision and Pattern Recognition · Computer Science 2024-10-15 Saba Fatema , Brighton Nuwagira , Sayoni Chakraborty , Reyhan Gedik , Baris Coskunuzer

The rapid growth of dermatological imaging and mobile diagnostic tools calls for systems that not only demonstrate empirical performance but also provide strong theoretical guarantees. Deep learning models have shown high predictive…

Machine Learning · Computer Science 2026-01-07 Rohit Kaushik , Eva Kaushik