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Motivation: Multi-omics integration can improve cancer subtyping, but modality informativeness and noise vary across cancer types and patients. Existing graph-based methods optimize modality weights jointly with the classification objective…

Machine Learning · Computer Science 2026-04-28 Boyang Fan , Hengchuang Yin , Siyu Yi , Yifan Wang , Zhicheng Li , Leijiyu Zhou , Jiancheng Lv , Wei Ju

Lung and colon cancer are serious worldwide health challenges that require early and precise identification to reduce mortality risks. However, diagnosis, which is mostly dependent on histopathologists' competence, presents difficulties and…

Image and Video Processing · Electrical Eng. & Systems 2024-05-15 Mukaffi Bin Moin , Fatema Tuj Johora Faria , Swarnajit Saha , Busra Kamal Rafa , Mohammad Shafiul Alam

Deep one-class classification variants for anomaly detection learn a mapping that concentrates nominal samples in feature space causing anomalies to be mapped away. Because this transformation is highly non-linear, finding interpretations…

Computer Vision and Pattern Recognition · Computer Science 2021-03-19 Philipp Liznerski , Lukas Ruff , Robert A. Vandermeulen , Billy Joe Franks , Marius Kloft , Klaus-Robert Müller

Computer-aided diagnosis (CAD) based on histopathological imaging has progressed rapidly in recent years with the rise of machine learning based methodologies. Traditional approaches consist of training a classification model using features…

Computer Vision and Pattern Recognition · Computer Science 2019-03-29 Junaid Malik , Serkan Kiranyaz , Suchitra Kunhoth , Turker Ince , Somaya Al-Maadeed , Ridha Hamila , Moncef Gabbouj

The recent advancements in artificial intelligence (AI), with the release of several large models having only query access, make a strong case for explainability of deep models in a post-hoc gradient free manner. In this paper, we propose a…

Artificial Intelligence · Computer Science 2024-09-18 Debarpan Bhattacharya , Amir H. Poorjam , Deepak Mittal , Sriram Ganapathy

Continual learning, also known as lifelong learning or incremental learning, refers to the process by which a model learns from a stream of incoming data over time. A common problem in continual learning is the classification layer's bias…

Computer Vision and Pattern Recognition · Computer Science 2025-01-27 Haoran Chen , Micah Goldblum , Zuxuan Wu , Yu-Gang Jiang

In routine colorectal cancer management, histologic samples stained with hematoxylin and eosin are commonly used. Nonetheless, their potential for defining objective biomarkers for patient stratification and treatment selection is still…

Quantitative Methods · Quantitative Biology 2024-09-26 Fabi Prezja , Leevi Annala , Sampsa Kiiskinen , Suvi Lahtinen , Timo Ojala , Pekka Ruusuvuori , Teijo Kuopio

Gradient-weighted Class Activation Mapping (Grad- CAM), is an example-based explanation method that provides a gradient activation heat map as an explanation for Convolution Neural Network (CNN) models. The drawback of this method is that…

Computer Vision and Pattern Recognition · Computer Science 2022-04-13 Tanmay Chakraborty , Utkarsh Trehan , Khawla Mallat , Jean-Luc Dugelay

Detecting cancers at early stages can dramatically reduce mortality rates. Therefore, practical cancer screening at the population level is needed. Here, we develop a comprehensive detection system to classify all common cancer types. By…

Molecular Networks · Quantitative Biology 2021-03-30 Anyou Wang , Rong Hai , Paul J Rider , Qianchuan He

Accurate and reliable histopathological image classification is essential for breast cancer diagnosis. However, many deep learning models remain sensitive to magnification variability and lack interpretability. To address these challenges,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Enam Ahmed Taufika , Md Ahasanul Arafatha , Abhijit Kumar Ghoshb , Md. Tanzim Rezab , Md Ashad Alamc

In recent years, there has been a significant surge in malware attacks, necessitating more advanced preventive measures and remedial strategies. While several successful AI-based malware classification approaches exist categorized into…

Cryptography and Security · Computer Science 2024-04-22 Quincy Card , Daniel Simpson , Kshitiz Aryal , Maanak Gupta , Sheikh Rabiul Islam

Purpose: To develop high throughput multi-label annotators for body (chest, abdomen, and pelvis) Computed Tomography (CT) reports that can be applied across a variety of abnormalities, organs, and disease states. Approach: We used a…

Identifying cell types and subtypes in routine histopathology is fundamental for understanding disease. Existing tile-based models capture nuclear detail but miss the broader tissue context that influences cell identity. Current human…

Computer Vision and Pattern Recognition · Computer Science 2025-11-20 Yinuo Xu , Yan Cui , Mingyao Li , Zhi Huang

Adopting Convolutional Neural Networks (CNNs) in the daily routine of primary diagnosis requires not only near-perfect precision, but also a sufficient degree of generalization to data acquisition shifts and transparency. Existing CNN…

Computer Vision and Pattern Recognition · Computer Science 2023-06-22 Mara Graziani , Sebastian Otalora , Stephane Marchand-Maillet , Henning Muller , Vincent Andrearczyk

Early detection of lung cancer is critical to improving survival outcomes. We present a deep learning framework for automated lung cancer screening from chest computed tomography (CT) images with integrated explainability. Using the…

Image and Video Processing · Electrical Eng. & Systems 2026-01-07 Nishan Rai , Sujan Khatri , Devendra Risal

Deep neural networks have demonstrated promising performance on image recognition tasks. However, they may heavily rely on confounding factors, using irrelevant artifacts or bias within the dataset as the cue to improve performance. When a…

Computer Vision and Pattern Recognition · Computer Science 2023-03-03 Siyuan Yan , Zhen Yu , Xuelin Zhang , Dwarikanath Mahapatra , Shekhar S. Chandra , Monika Janda , Peter Soyer , Zongyuan Ge

Understanding how deep learning models predict oncology patient risk can provide critical insights into disease progression, support clinical decision-making, and pave the way for trustworthy and data-driven precision medicine. Building on…

Computer Vision and Pattern Recognition · Computer Science 2024-11-13 Marvin Sextro , Gabriel Dernbach , Kai Standvoss , Simon Schallenberg , Frederick Klauschen , Klaus-Robert Müller , Maximilian Alber , Lukas Ruff

Much effort has been devoted to understanding the decisions of deep neural networks in recent years. A number of model-aware saliency methods were proposed to explain individual classification decisions by creating saliency maps. However,…

Machine Learning · Computer Science 2020-06-09 Jindong Gu , Volker Tresp

Automatic Modulation Classification (AMC) plays a significant role in modern cognitive and intelligent radio systems, where accurate identification of modulation is crucial for adaptive communication. The presence of heterogeneous wireless…

Signal Processing · Electrical Eng. & Systems 2025-08-12 K. A. Shahriar

Reliable and interpretable tumor classification from clinical imaging remains a core challenge. The main difficulties arise from heterogeneous modality quality, limited annotations, and the absence of structured anatomical guidance. We…

Image and Video Processing · Electrical Eng. & Systems 2025-10-21 Hongzhao Chen , Hexiao Ding , Yufeng Jiang , Jing Lan , Ka Chun Li , Gerald W. Y. Cheng , Nga-Chun Ng , Yao Pu , Jing Cai , Liang-ting Lin , Jung Sun Yoo
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